Resveratrol_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in SW 1088 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.115321
ERRFI1 ERBB receptor feedback inhibitor 1 0.112363
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0693844
ZBTB20 zinc finger and BTB domain containing 20 0.053966
COL5A1 collagen, type V, alpha 1 0.0508811
EGFR epidermal growth factor receptor 0.0496638
ESYT2 extended synaptotagmin-like protein 2 0.0477584
AHNAK AHNAK nucleoprotein 0.0457251
RAI14 retinoic acid induced 14 0.0422321
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0421912
LIMS1 LIM and senescent cell antigen-like domains 1 0.0410558
FAM13A family with sequence similarity 13, member A 0.0409957
AKAP9 A kinase (PRKA) anchor protein 9 0.0393285
TTC3 tetratricopeptide repeat domain 3 0.0365632
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0347846
F3 coagulation factor III (thromboplastin, tissue factor) 0.0337645
TRIO trio Rho guanine nucleotide exchange factor 0.0333512
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0324544
GCC2 GRIP and coiled-coil domain containing 2 0.0313164
NAV1 neuron navigator 1 0.0294499
TMEM165 transmembrane protein 165 0.0290894
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0289658
IQGAP1 IQ motif containing GTPase activating protein 1 0.0284888
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0273323
TNS3 tensin 3 0.0272906
SEC31A SEC31 homolog A (S. cerevisiae) 0.0272461
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0271687
BACE2 beta-site APP-cleaving enzyme 2 0.0271019
SEC24A SEC24 family member A 0.027022
TIMP3 TIMP metallopeptidase inhibitor 3 0.0268892
HMGA2 high mobility group AT-hook 2 0.0268224
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0262241
GOLGA4 golgin A4 0.0261681
GOLGB1 golgin B1 0.0257652
ZNF395 zinc finger protein 395 0.0254806
FNIP1 folliculin interacting protein 1 0.0254697
SND1 staphylococcal nuclease and tudor domain containing 1 0.0253215
RARS1 arginyl-tRNA synthetase 1 0.0252189
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.025168
MARCHF6 membrane associated ring-CH-type finger 6 0.0251635
SAMD4A sterile alpha motif domain containing 4A 0.0244427
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0243152
JARID2 jumonji, AT rich interactive domain 2 0.0238212
DPYD dihydropyrimidine dehydrogenase 0.0237073
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0236589
MXI1 MAX interactor 1, dimerization protein 0.0236215
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0234295
FGFR2 fibroblast growth factor receptor 2 0.0232194
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0229598
CDK13 cyclin-dependent kinase 13 0.0227757
KMT2C lysine (K)-specific methyltransferase 2C 0.0227319
COPA coatomer protein complex, subunit alpha 0.0226373
COL4A1 collagen, type IV, alpha 1 0.0224215
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0222734
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0221962
SEPTIN9 septin 9 0.0221827
ZCCHC7 zinc finger, CCHC domain containing 7 0.022052
AKAP12 A kinase (PRKA) anchor protein 12 0.0220197
CHD9 chromodomain helicase DNA binding protein 9 0.0220164
LOXL2 lysyl oxidase-like 2 0.0219433
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.021784
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.0217766
SDC4 syndecan 4 0.021348
COG6 component of oligomeric golgi complex 6 0.0212662
MON2 MON2 homolog (S. cerevisiae) 0.0212537
NRXN3 neurexin 3 0.0211165
SCAF11 SR-related CTD-associated factor 11 0.0210254
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.020849
COL6A2 collagen, type VI, alpha 2 0.0206345
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0206152
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0206004
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0205439
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0204827
TTC17 tetratricopeptide repeat domain 17 0.020455
PIBF1 progesterone immunomodulatory binding factor 1 0.0204184
CDH13 cadherin 13 0.0201194
SEC24D SEC24 family member D 0.0201069
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0200757
CANX calnexin 0.020051
HIPK2 homeodomain interacting protein kinase 2 0.0200393
RND3 Rho family GTPase 3 0.0199324
CLMP CXADR-like membrane protein 0.019795
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0193083
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0193083
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0192469
PGM3 phosphoglucomutase 3 0.0192414
DNPEP aspartyl aminopeptidase 0.0191781
DNAAF9 dynein axonemal assembly factor 9 0.0191694
IGFBP3 insulin-like growth factor binding protein 3 0.0187981
YEATS2 YEATS domain containing 2 0.0187425
MYO9A myosin IXA 0.018742
ZMIZ1 zinc finger, MIZ-type containing 1 0.0187042
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0185758
KDM2A lysine (K)-specific demethylase 2A 0.0185279
ANKHD1 ankyrin repeat and KH domain containing 1 0.0185269
ARHGAP22 Rho GTPase activating protein 22 0.0184081
METTL16 methyltransferase like 16 0.0184015
ANXA5 annexin A5 0.0181971
HDLBP high density lipoprotein binding protein 0.0179609
DHRSX dehydrogenase/reductase (SDR family) X-linked 0.0179536

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.213398
MT2A metallothionein 2A -0.146402
TMSB10 thymosin beta 10 -0.14561
PTMA prothymosin, alpha -0.105076
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0756621
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.054101
EGR1 early growth response 1 -0.0429536
PDLIM5 PDZ and LIM domain 5 -0.0408709
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0408676
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0395105
HLA-B major histocompatibility complex, class I, B -0.0393953
RPS6 ribosomal protein S6 -0.0386797
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0378032
QKI QKI, KH domain containing, RNA binding -0.0375339
S100A6 S100 calcium binding protein A6 -0.037058
TGFBI transforming growth factor, beta-induced, 68kDa -0.036333
COL1A1 collagen, type I, alpha 1 -0.0363126
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0356327
TPT1 tumor protein, translationally-controlled 1 -0.0341643
PKM pyruvate kinase, muscle -0.033973
B2M beta-2-microglobulin -0.0322035
MAP1B microtubule-associated protein 1B -0.0318521
FTL ferritin, light polypeptide -0.0316029
PTN pleiotrophin -0.0312995
LGALS1 lectin, galactoside-binding, soluble, 1 -0.03125
VCL vinculin -0.0312333
RPS19 ribosomal protein S19 -0.0311279
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0310306
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0303809
PFN1 profilin 1 -0.0297641
HLA-C major histocompatibility complex, class I, C -0.0291898
VIM vimentin -0.029057
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0288653
FBXO11 F-box protein 11 -0.028745
RPS3 ribosomal protein S3 -0.02855
TPM4 tropomyosin 4 -0.0284925
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0282777
BASP1 brain abundant, membrane attached signal protein 1 -0.0281831
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.027874
S100A9 S100 calcium binding protein A9 -0.0267632
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.026744
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0265102
SPAG9 sperm associated antigen 9 -0.0254047
RPS24 ribosomal protein S24 -0.025222
ADM adrenomedullin -0.0251237
RPL23 ribosomal protein L23 -0.0250708
EIF5B eukaryotic translation initiation factor 5B -0.0250522
FOSL1 FOS-like antigen 1 -0.0248827
CCNI cyclin I -0.0242191
COL1A2 collagen, type I, alpha 2 -0.0238489
KTN1 kinectin 1 (kinesin receptor) -0.0237963
PSD3 pleckstrin and Sec7 domain containing 3 -0.0235154
H3-3B H3.3 histone B -0.0234866
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.0234023
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0232413
PRRC2C proline-rich coiled-coil 2C -0.0232081
JMJD1C jumonji domain containing 1C -0.0231733
PDE10A phosphodiesterase 10A -0.0229323
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0228805
RPS8 ribosomal protein S8 -0.0225419
ZFAND3 zinc finger, AN1-type domain 3 -0.0221218
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0220478
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0215983
GPC6 glypican 6 -0.0215864
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0215502
RPL19 ribosomal protein L19 -0.0213897
ASPH aspartate beta-hydroxylase -0.0210578
VMP1 vacuole membrane protein 1 -0.0210149
NDUFA4 NDUFA4, mitochondrial complex associated -0.0206414
RPL32 ribosomal protein L32 -0.0206232
NIPBL Nipped-B homolog (Drosophila) -0.0204037
TXNRD1 thioredoxin reductase 1 -0.0203832
WTAP Wilms tumor 1 associated protein -0.0202281
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0202212
SDC2 syndecan 2 -0.0201124
MT1X metallothionein 1X -0.0201089
RPL30 ribosomal protein L30 -0.0199913
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0198435
RPL35A ribosomal protein L35a -0.019478
RPLP0 ribosomal protein, large, P0 -0.0191624
CD99 CD99 molecule -0.0189255
UGCG UDP-glucose ceramide glucosyltransferase -0.0189157
RTN4 reticulon 4 -0.0188592
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0185298
ZFP36L1 ZFP36 ring finger protein-like 1 -0.018424
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0183261
RPL12 ribosomal protein L12 -0.0182909
ITGAV integrin, alpha V -0.0180573
CKAP4 cytoskeleton-associated protein 4 -0.017998
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0179869
FNDC3A fibronectin type III domain containing 3A -0.0179167
POMP proteasome maturation protein -0.0175043
SON SON DNA binding protein -0.0173946
RNF213 ring finger protein 213 -0.0172475
RPL36 ribosomal protein L36 -0.0172473
TPI1 triosephosphate isomerase 1 -0.0172264
ENO1 enolase 1, (alpha) -0.0172158
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0170255
CSNK1A1 casein kinase 1, alpha 1 -0.0170226
GNAS GNAS complex locus -0.0169368