Resveratrol_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in SW 1271 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 0.173928
DNER delta/notch-like EGF repeat containing 0.0625406
ANXA1 annexin A1 0.0575671
NAMPT nicotinamide phosphoribosyltransferase 0.0534834
HILPDA hypoxia inducible lipid droplet-associated 0.0492035
TXNRD1 thioredoxin reductase 1 0.0478221
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0467853
BASP1 brain abundant, membrane attached signal protein 1 0.0445203
DSCAM Down syndrome cell adhesion molecule 0.0417644
DERA deoxyribose-phosphate aldolase (putative) 0.0408884
EEF2 eukaryotic translation elongation factor 2 0.0397072
CYTH1 cytohesin 1 0.0392374
LPP LIM domain containing preferred translocation partner in lipoma 0.0383398
CEP250 centrosomal protein 250kDa 0.0373953
MBNL2 muscleblind-like splicing regulator 2 0.0373341
SP100 SP100 nuclear antigen 0.0366398
ANO6 anoctamin 6 0.0364599
PCBP2 poly(rC) binding protein 2 0.0362784
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0350724
MBNL1 muscleblind-like splicing regulator 1 0.034648
LUZP1 leucine zipper protein 1 0.0341926
SSH2 slingshot protein phosphatase 2 0.0330487
FAM13A family with sequence similarity 13, member A 0.0326921
SMYD3 SET and MYND domain containing 3 0.0324846
RAD50 RAD50 homolog (S. cerevisiae) 0.0322913
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0317262
ZNF609 zinc finger protein 609 0.0312766
ANKRD28 ankyrin repeat domain 28 0.0312574
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0308948
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.0308001
CLTC clathrin, heavy chain (Hc) 0.0307176
ARL15 ADP-ribosylation factor-like 15 0.0306967
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.0306209
APLP2 amyloid beta (A4) precursor-like protein 2 0.0305385
WDPCP WD repeat containing planar cell polarity effector 0.0304655
APP amyloid beta (A4) precursor protein 0.0301727
DGKD diacylglycerol kinase, delta 130kDa 0.0298364
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0297448
PYGL phosphorylase, glycogen, liver 0.0294994
MORF4L2 mortality factor 4 like 2 0.0293586
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0290378
CEMIP2 cell migration inducing hyaluronidase 2 0.028706
SOD2 superoxide dismutase 2, mitochondrial 0.028645
ZEB1 zinc finger E-box binding homeobox 1 0.028472
CAPRIN2 caprin family member 2 0.0283126
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0281724
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.028086
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0279412
AHNAK AHNAK nucleoprotein 0.0278595
ESYT2 extended synaptotagmin-like protein 2 0.0278395
SPAG9 sperm associated antigen 9 0.0273012
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.0272328
KIAA1958 KIAA1958 0.0270314
GOLGB1 golgin B1 0.0270013
ZNF292 zinc finger protein 292 0.0269896
TXNIP thioredoxin interacting protein 0.0269322
XPO1 exportin 1 0.0265956
CREBRF CREB3 regulatory factor 0.0264539
MYH9 myosin, heavy chain 9, non-muscle 0.0264077
SPIDR scaffolding protein involved in DNA repair 0.026326
AVL9 AVL9 homolog (S. cerevisiase) 0.0262684
NXN nucleoredoxin 0.0261875
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.0260378
STAT1 signal transducer and activator of transcription 1, 91kDa 0.026
ATM ATM serine/threonine kinase 0.0259504
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.0258384
ATG7 autophagy related 7 0.0258216
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.025766
NF1 neurofibromin 1 0.0257658
TNIP1 TNFAIP3 interacting protein 1 0.0255346
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0255279
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.0255104
CANX calnexin 0.0251214
TBC1D5 TBC1 domain family, member 5 0.0250659
NAP1L1 nucleosome assembly protein 1-like 1 0.0247272
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0245154
SCAPER S-phase cyclin A-associated protein in the ER 0.0244175
TRIO trio Rho guanine nucleotide exchange factor 0.0243804
WDFY2 WD repeat and FYVE domain containing 2 0.0240797
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0239744
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0238922
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0238863
RAB5A RAB5A, member RAS oncogene family 0.0237756
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0236237
AKAP9 A kinase (PRKA) anchor protein 9 0.0236092
FLNB filamin B, beta 0.0233975
IL1RAP interleukin 1 receptor accessory protein 0.023261
CEP290 centrosomal protein 290kDa 0.0232207
SYCP2 synaptonemal complex protein 2 0.0231832
YAP1 Yes-associated protein 1 0.0230496
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0230113
KTN1 kinectin 1 (kinesin receptor) 0.0229901
ZNF438 zinc finger protein 438 0.0229602
RAD51B RAD51 paralog B 0.0229592
PNN pinin, desmosome associated protein 0.0227753
EPAS1 endothelial PAS domain protein 1 0.0226777
AHR aryl hydrocarbon receptor 0.0225349
MRE11 MRE11 homolog, double strand break repair nuclease 0.0225087
FER fer (fps/fes related) tyrosine kinase 0.0224659
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.0224198

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.379745
TPT1 tumor protein, translationally-controlled 1 -0.107519
VIM vimentin -0.106069
POTEF POTE ankyrin domain family, member F -0.0858277
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0611475
ANXA2 annexin A2 -0.058285
TMSB10 thymosin beta 10 -0.0579514
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0522203
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0465538
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0454187
PODXL podocalyxin-like -0.0438121
HMGA2 high mobility group AT-hook 2 -0.0415707
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0411002
ENO1 enolase 1, (alpha) -0.0392244
PRSS23 protease, serine, 23 -0.0387595
LMO7 LIM domain 7 -0.03842
RAI14 retinoic acid induced 14 -0.0378225
PRKCA protein kinase C, alpha -0.0370215
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0367639
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0361811
ZFHX3 zinc finger homeobox 3 -0.0361415
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0360805
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0357088
TPI1 triosephosphate isomerase 1 -0.0354623
TM4SF1 transmembrane 4 L six family member 1 -0.0344121
BBX bobby sox homolog (Drosophila) -0.033738
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0336711
B2M beta-2-microglobulin -0.0335596
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0334845
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0332262
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0327811
PFN1 profilin 1 -0.0327719
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0327474
NALCN sodium leak channel, non selective -0.0326938
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.031892
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0313472
PRR16 proline rich 16 -0.0309264
IER3 immediate early response 3 -0.0308041
S100A6 S100 calcium binding protein A6 -0.0307908
MT2A metallothionein 2A -0.0303402
FMN1 formin 1 -0.0300198
ACTG1 actin gamma 1 -0.029577
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0292672
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0292322
BTG1 B-cell translocation gene 1, anti-proliferative -0.0283655
TBCA tubulin folding cofactor A -0.0281759
WARS1 tryptophanyl-tRNA synthetase 1 -0.0279591
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0274969
RPS8 ribosomal protein S8 -0.026947
GPATCH2L G patch domain containing 2-like -0.0267908
UBC ubiquitin C -0.0266946
RPS21 ribosomal protein S21 -0.0265143
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0264993
KLF6 Kruppel-like factor 6 -0.0264862
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0262211
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0260948
BIRC6 baculoviral IAP repeat containing 6 -0.0258999
TMEM14B transmembrane protein 14B -0.0258831
JARID2 jumonji, AT rich interactive domain 2 -0.0258072
NLK nemo-like kinase -0.0255914
RACK1 receptor for activated C kinase 1 -0.0255409
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0252709
ZFAND3 zinc finger, AN1-type domain 3 -0.0249733
SVIL supervillin -0.0248751
LRP6 low density lipoprotein receptor-related protein 6 -0.024667
TTC14 tetratricopeptide repeat domain 14 -0.0246438
CLIP2 CAP-GLY domain containing linker protein 2 -0.0246428
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 -0.0240216
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0240115
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0239082
CDK6 cyclin-dependent kinase 6 -0.0238753
SAR1A secretion associated, Ras related GTPase 1A -0.0238582
PURA purine-rich element binding protein A -0.023595
DEK DEK proto-oncogene -0.0234861
RPS13 ribosomal protein S13 -0.0234118
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0232993
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0231963
HLA-B major histocompatibility complex, class I, B -0.0231071
PTPRG protein tyrosine phosphatase, receptor type, G -0.0227201
GSK3B glycogen synthase kinase 3 beta -0.0227061
NT5E 5'-nucleotidase, ecto (CD73) -0.0227052
AGO3 argonaute RISC catalytic component 3 -0.0226287
RPS19 ribosomal protein S19 -0.0223526
ARMH4 armadillo like helical domain containing 4 -0.0223018
RPL9 ribosomal protein L9 -0.0222463
CHD4 chromodomain helicase DNA binding protein 4 -0.0220188
ENO2 enolase 2 (gamma, neuronal) -0.0220136
ACER3 alkaline ceramidase 3 -0.0219792
RORA RAR-related orphan receptor A -0.021895
S100A10 S100 calcium binding protein A10 -0.0217598
ISG15 ISG15 ubiquitin-like modifier -0.0215664
CCDC50 coiled-coil domain containing 50 -0.0215426
RPS23 ribosomal protein S23 -0.0211719
ZBTB20 zinc finger and BTB domain containing 20 -0.0210852
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0210502
BIRC2 baculoviral IAP repeat containing 2 -0.0210071
SNX14 sorting nexin 14 -0.0209769
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0208072
MYO10 myosin X -0.0206315
GNAS GNAS complex locus -0.020609