Resveratrol_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in SW 900 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
STC2 stanniocalcin 2 0.10527
CXCL8 chemokine (C-X-C motif) ligand 8 0.0968875
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0786118
FTH1 ferritin, heavy polypeptide 1 0.0698818
CD109 CD109 molecule 0.0675898
VEGFA vascular endothelial growth factor A 0.0533343
HILPDA hypoxia inducible lipid droplet-associated 0.0505432
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0477554
SOS1 son of sevenless homolog 1 (Drosophila) 0.0424459
FAM13A family with sequence similarity 13, member A 0.0424239
RNF145 ring finger protein 145 0.0377628
AKAP12 A kinase (PRKA) anchor protein 12 0.0368055
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0314843
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0302702
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0302075
CADM1 cell adhesion molecule 1 0.0296823
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0296097
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0294774
HIPK2 homeodomain interacting protein kinase 2 0.029442
TMEM156 transmembrane protein 156 0.0290657
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0258467
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0252905
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0242782
SUCO SUN domain containing ossification factor 0.024264
SEC23A Sec23 homolog A (S. cerevisiae) 0.0240778
SMAD3 SMAD family member 3 0.0234564
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0233505
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.0233188
SOD2 superoxide dismutase 2, mitochondrial 0.0231668
PCBP2 poly(rC) binding protein 2 0.02316
CREBRF CREB3 regulatory factor 0.0229466
RB1CC1 RB1-inducible coiled-coil 1 0.0228121
CDC73 cell division cycle 73 0.0225332
PDIA3 protein disulfide isomerase family A, member 3 0.0222092
ESYT2 extended synaptotagmin-like protein 2 0.0217306
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0216662
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.021655
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0215915
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0214558
PDIA4 protein disulfide isomerase family A, member 4 0.0212242
AHRR aryl-hydrocarbon receptor repressor 0.0210701
NUP58 nucleoporin 58 0.0203695
RIOK3 RIO kinase 3 0.019989
ZNF292 zinc finger protein 292 0.01996
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0198876
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0196669
COPA coatomer protein complex, subunit alpha 0.0192642
CCNL1 cyclin L1 0.0189643
RYBP RING1 and YY1 binding protein 0.0184799
ADAM17 ADAM metallopeptidase domain 17 0.0184263
RAB8B RAB8B, member RAS oncogene family 0.0182407
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0181706
FXR1 fragile X mental retardation, autosomal homolog 1 0.0179547
FOSL1 FOS-like antigen 1 0.0179142
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0178521
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.017686
SIRT1 sirtuin 1 0.0173121
HELZ helicase with zinc finger 0.0170227
RICTOR RPTOR independent companion of MTOR, complex 2 0.016773
SNX9 sorting nexin 9 0.0166249
APLP2 amyloid beta (A4) precursor-like protein 2 0.0165612
ZCCHC7 zinc finger, CCHC domain containing 7 0.0164033
TXNIP thioredoxin interacting protein 0.0162408
MTMR3 myotubularin related protein 3 0.0161788
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0160962
UBA6 ubiquitin-like modifier activating enzyme 6 0.0160918
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0160139
PER1 period circadian clock 1 0.0159281
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0158847
PLIN2 perilipin 2 0.0158381
FOXO3 forkhead box O3 0.0157363
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0155687
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0155476
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0154739
MIDEAS mitotic deacetylase associated SANT domain protein 0.0154218
TPR translocated promoter region, nuclear basket protein 0.0151875
RND3 Rho family GTPase 3 0.0150946
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0150779
NEK7 NIMA-related kinase 7 0.0149611
ZFP36L1 ZFP36 ring finger protein-like 1 0.0149162
TFG TRK-fused gene 0.0146764
USP3 ubiquitin specific peptidase 3 0.0146166
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0144967
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0142361
KMT2E lysine (K)-specific methyltransferase 2E 0.0141795
JARID2 jumonji, AT rich interactive domain 2 0.0140474
KDM2A lysine (K)-specific demethylase 2A 0.0138727
ADAM9 ADAM metallopeptidase domain 9 0.0136728
RAB18 RAB18, member RAS oncogene family 0.0135774
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0135716
XPO1 exportin 1 0.0135305
KLHL24 kelch-like family member 24 0.0135204
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0134684
ALKBH5 AlkB family member 5, RNA demethylase 0.0134213
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0134169
FERMT2 fermitin family member 2 0.0133558
TTC3 tetratricopeptide repeat domain 3 0.013317
DENND5B DENN/MADD domain containing 5B 0.0132759
HYOU1 hypoxia up-regulated 1 0.0129758
EZR ezrin 0.0129149

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.280794
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.266258
TMSB10 thymosin beta 10 -0.117214
NRG1 neuregulin 1 -0.104791
MT2A metallothionein 2A -0.100358
ASPH aspartate beta-hydroxylase -0.0987463
VCL vinculin -0.0831105
VIM vimentin -0.0812418
GLIS3 GLIS family zinc finger 3 -0.0768659
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0754653
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0735218
S100A6 S100 calcium binding protein A6 -0.0721663
HMGA2 high mobility group AT-hook 2 -0.0678909
PTMA prothymosin, alpha -0.0671458
OSMR oncostatin M receptor -0.0646432
HLA-B major histocompatibility complex, class I, B -0.0574129
TPT1 tumor protein, translationally-controlled 1 -0.0534887
EFNA5 ephrin-A5 -0.0513357
EXT1 exostosin glycosyltransferase 1 -0.0508281
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0485654
SYT1 synaptotagmin I -0.0484581
MBD5 methyl-CpG binding domain protein 5 -0.046561
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0435201
MAP1B microtubule-associated protein 1B -0.0430898
IFI27 interferon, alpha-inducible protein 27 -0.0426874
IER3 immediate early response 3 -0.0405931
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0404702
STAT1 signal transducer and activator of transcription 1, 91kDa -0.040224
ZMYND8 zinc finger, MYND-type containing 8 -0.0400561
IFI6 interferon, alpha-inducible protein 6 -0.039966
ACTG1 actin gamma 1 -0.0392747
RPLP1 ribosomal protein, large, P1 -0.0387834
SMYD3 SET and MYND domain containing 3 -0.0378536
GNAS GNAS complex locus -0.0376971
RPS19 ribosomal protein S19 -0.0374989
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.037361
IFI16 interferon, gamma-inducible protein 16 -0.036862
ZBTB20 zinc finger and BTB domain containing 20 -0.036681
MKI67 marker of proliferation Ki-67 -0.0361119
ETV1 ets variant 1 -0.0356983
TAS2R14 taste receptor, type 2, member 14 -0.0354942
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0354705
FTL ferritin, light polypeptide -0.0354213
RPL37A ribosomal protein L37a -0.0349937
RPL9 ribosomal protein L9 -0.0348282
RPS24 ribosomal protein S24 -0.0345314
ITGA1 integrin, alpha 1 -0.0341045
TMSB4X thymosin beta 4, X-linked -0.0336821
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0330716
S100A10 S100 calcium binding protein A10 -0.0330327
RNF213 ring finger protein 213 -0.0329091
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0323338
DST dystonin -0.0321429
TM4SF1 transmembrane 4 L six family member 1 -0.0319316
FOXP1 forkhead box P1 -0.0315922
RPS27A ribosomal protein S27a -0.0315093
TPI1 triosephosphate isomerase 1 -0.0311825
RPS21 ribosomal protein S21 -0.0305555
PRELID2 PRELI domain containing 2 -0.0302068
RPL35A ribosomal protein L35a -0.0299582
RPL19 ribosomal protein L19 -0.0298406
H1-0 H1.0 linker histone -0.029629
AEBP2 AE binding protein 2 -0.0294979
RPS6 ribosomal protein S6 -0.0294246
EIF1 eukaryotic translation initiation factor 1 -0.0294185
RPLP2 ribosomal protein, large, P2 -0.0293923
RPS8 ribosomal protein S8 -0.0293541
AHR aryl hydrocarbon receptor -0.0284864
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0283364
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0280698
RPL38 ribosomal protein L38 -0.0279192
ENO1 enolase 1, (alpha) -0.0273234
RPL26 ribosomal protein L26 -0.0272298
PDE4D phosphodiesterase 4D, cAMP-specific -0.0271049
LRMDA leucine rich melanocyte differentiation associated -0.0267381
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0267366
TRIO trio Rho guanine nucleotide exchange factor -0.0265275
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0263391
MAML2 mastermind-like 2 (Drosophila) -0.0262548
RPL23 ribosomal protein L23 -0.026181
SLC38A2 solute carrier family 38, member 2 -0.0257776
RPLP0 ribosomal protein, large, P0 -0.0255107
SOX4 SRY (sex determining region Y)-box 4 -0.0253991
TOP1 topoisomerase (DNA) I -0.0252421
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0250018
CD44 CD44 molecule (Indian blood group) -0.0249153
NRP1 neuropilin 1 -0.0248431
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0247558
RPL34 ribosomal protein L34 -0.0247553
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0247464
RPS29 ribosomal protein S29 -0.0247152
NCOA7 nuclear receptor coactivator 7 -0.0245485
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0244783
DPYD dihydropyrimidine dehydrogenase -0.0241315
BPTF bromodomain PHD finger transcription factor -0.0239751
SFRP1 secreted frizzled-related protein 1 -0.023719
CAPN2 calpain 2, (m/II) large subunit -0.0234033
PRRC2C proline-rich coiled-coil 2C -0.0233826
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0233008
RRBP1 ribosome binding protein 1 -0.0230719