Retinal Pigment Epithelium Atrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description acquired diminution of the size of the epithelial layer of the retina composed of cells containing pigment granules, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes (Mammalian Phenotype Ontology, MP_0005548)
External Link https://www.disgenet.org/browser/0/1/0/C1720251
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Genes

7 genes associated with the disease Retinal Pigment Epithelium Atrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ARMS2 age-related maculopathy susceptibility 2
CFH complement factor H
HTRA1 HtrA serine peptidase 1
MFRP membrane frizzled-related protein
PLXNA2 plexin A2
RPE ribulose-5-phosphate-3-epimerase