Retinoblastoma gene in cancer Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP2446.html
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Genes

87 proteins participating in the Retinoblastoma gene in cancer pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ANLN anillin, actin binding protein
BARD1 BRCA1 associated RING domain 1
CCDC6 coiled-coil domain containing 6
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCND1 cyclin D1
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC45 cell division cycle 45
CDC7 cell division cycle 7
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
CHEK1 checkpoint kinase 1
DCK deoxycytidine kinase
DHFR dihydrofolate reductase
DNMT1 DNA (cytosine-5-)-methyltransferase 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
FAF1 Fas (TNFRSF6) associated factor 1
FANCG Fanconi anemia, complementation group G
H2AZ1 H2A.Z variant histone 1
HDAC1 histone deacetylase 1
HLTF helicase-like transcription factor
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
KIF4A kinesin family member 4A
MAPK13 mitogen-activated protein kinase 13
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPAT nuclear protein, ataxia-telangiectasia locus
ORC1 origin recognition complex, subunit 1
PCNA proliferating cell nuclear antigen
PLK4 polo-like kinase 4
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2 protein arginine methyltransferase 2
RABIF RAB interacting factor
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RBP1 retinol binding protein 1, cellular
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SAP30 Sin3A-associated protein, 30kDa
SIN3A SIN3 transcription regulator family member A
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
STMN1 stathmin 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TTK TTK protein kinase
TYMS thymidylate synthetase
WEE1 WEE1 G2 checkpoint kinase
ZNF655 zinc finger protein 655