| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Retinoic acid_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.142792 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.134184 |
| COL5A1 | collagen, type V, alpha 1 | 0.105229 |
| MAP1B | microtubule-associated protein 1B | 0.0974225 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0935217 |
| NAV1 | neuron navigator 1 | 0.0930219 |
| PODXL | podocalyxin-like | 0.0850031 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0833701 |
| FN1 | fibronectin 1 | 0.0816331 |
| EGFR | epidermal growth factor receptor | 0.0798656 |
| HDAC9 | histone deacetylase 9 | 0.0758462 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0714475 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0690746 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0684672 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.064212 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0608306 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0571957 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0564823 |
| DST | dystonin | 0.056369 |
| EFNA5 | ephrin-A5 | 0.0559266 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0542692 |
| PRELID2 | PRELI domain containing 2 | 0.0541512 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0497328 |
| ASPH | aspartate beta-hydroxylase | 0.0495536 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0450831 |
| NAV2 | neuron navigator 2 | 0.0441235 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0434456 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0424337 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0413607 |
| PLXNA2 | plexin A2 | 0.0412075 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0408147 |
| CYTH3 | cytohesin 3 | 0.0404375 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0401739 |
| FLNA | filamin A, alpha | 0.0401626 |
| RIGI | RNA sensor RIG-I | 0.0400803 |
| RUNX1 | runt-related transcription factor 1 | 0.0395684 |
| SEPTIN9 | septin 9 | 0.0395443 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0386172 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0383038 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0382169 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0379153 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0379026 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0364243 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0361988 |
| SMAD3 | SMAD family member 3 | 0.0357536 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0355971 |
| TPM3 | tropomyosin 3 | 0.0355309 |
| GLIS3 | GLIS family zinc finger 3 | 0.0353897 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.035054 |
| SMYD3 | SET and MYND domain containing 3 | 0.0349246 |
| MSN | moesin | 0.0342387 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0342252 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0341473 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.033601 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0323655 |
| PLEC | plectin | 0.03196 |
| INTS6 | integrator complex subunit 6 | 0.031688 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0316113 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0312306 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0301657 |
| RASAL2 | RAS protein activator like 2 | 0.029614 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0295414 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294336 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0294148 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0292302 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0291528 |
| TENM3 | teneurin transmembrane protein 3 | 0.0290486 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0290355 |
| VCL | vinculin | 0.0289661 |
| MYOF | myoferlin | 0.0282094 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0281789 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0276638 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0275306 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0274678 |
| PRKCE | protein kinase C, epsilon | 0.0272667 |
| FMN2 | formin 2 | 0.0266596 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0266176 |
| CUX1 | cut-like homeobox 1 | 0.0263635 |
| APP | amyloid beta (A4) precursor protein | 0.0263345 |
| TAOK1 | TAO kinase 1 | 0.0262603 |
| PDLIM5 | PDZ and LIM domain 5 | 0.026243 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0261208 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0258936 |
| VEGFC | vascular endothelial growth factor C | 0.0258566 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0257092 |
| DCLK2 | doublecortin-like kinase 2 | 0.025017 |
| RNF144A | ring finger protein 144A | 0.0247842 |
| SP100 | SP100 nuclear antigen | 0.0244947 |
| GOLGB1 | golgin B1 | 0.0242909 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0242204 |
| TLE4 | transducin-like enhancer of split 4 | 0.0238464 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0238119 |
| DIAPH3 | diaphanous-related formin 3 | 0.0238026 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0237808 |
| MCL1 | myeloid cell leukemia 1 | 0.0236866 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0236382 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0234697 |
| PKM | pyruvate kinase, muscle | 0.0232519 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0231818 |
| E2F7 | E2F transcription factor 7 | 0.0231055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.187326 |
| MT2A | metallothionein 2A | -0.168317 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125278 |
| FBN1 | fibrillin 1 | -0.121331 |
| VIM | vimentin | -0.121006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.120895 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.092786 |
| PTMA | prothymosin, alpha | -0.0776332 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0750607 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0717227 |
| LOX | lysyl oxidase | -0.0691051 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0687534 |
| NDRG1 | N-myc downstream regulated 1 | -0.0673322 |
| UBC | ubiquitin C | -0.0654634 |
| COL1A2 | collagen, type I, alpha 2 | -0.0621684 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0604035 |
| PLAT | plasminogen activator, tissue | -0.0565373 |
| COL3A1 | collagen, type III, alpha 1 | -0.0546367 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0498282 |
| CSTB | cystatin B (stefin B) | -0.048892 |
| STC1 | stanniocalcin 1 | -0.0485572 |
| MT1X | metallothionein 1X | -0.0483339 |
| HLA-B | major histocompatibility complex, class I, B | -0.0471978 |
| B2M | beta-2-microglobulin | -0.0439993 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438142 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0425947 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0409054 |
| LOXL2 | lysyl oxidase-like 2 | -0.0408668 |
| S100A6 | S100 calcium binding protein A6 | -0.0393819 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0382678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0378227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0375853 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0370382 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.036742 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.036473 |
| WTAP | Wilms tumor 1 associated protein | -0.0361581 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0360366 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0355837 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0352219 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0351139 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0346399 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0329016 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0328557 |
| IER3 | immediate early response 3 | -0.0327928 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0316108 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0313615 |
| OGA | O-GlcNAcase | -0.0311641 |
| FTL | ferritin, light polypeptide | -0.0309114 |
| S100A10 | S100 calcium binding protein A10 | -0.0298306 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0295694 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0294192 |
| GNAS | GNAS complex locus | -0.0293862 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0282002 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0278557 |
| THBS2 | thrombospondin 2 | -0.0278512 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0270456 |
| RPL23 | ribosomal protein L23 | -0.026737 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0266601 |
| KLF6 | Kruppel-like factor 6 | -0.0265084 |
| TMSB4X | thymosin beta 4, X-linked | -0.026498 |
| CD99 | CD99 molecule | -0.0257899 |
| RPL35A | ribosomal protein L35a | -0.0255799 |
| RPL12 | ribosomal protein L12 | -0.0253197 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0250218 |
| SBF2 | SET binding factor 2 | -0.024726 |
| FAM162A | family with sequence similarity 162, member A | -0.0245403 |
| RPL34 | ribosomal protein L34 | -0.0243965 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0241288 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.024014 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0235028 |
| ADM | adrenomedullin | -0.0229962 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0227078 |
| INSIG1 | insulin induced gene 1 | -0.0225362 |
| RPS6 | ribosomal protein S6 | -0.022459 |
| CLU | clusterin | -0.0223754 |
| RPS24 | ribosomal protein S24 | -0.0223609 |
| HLA-E | major histocompatibility complex, class I, E | -0.0218831 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0215551 |
| RPS19 | ribosomal protein S19 | -0.0214126 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0213983 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0213573 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0210833 |
| WDR45B | WD repeat domain 45B | -0.0206799 |
| TMOD1 | tropomodulin 1 | -0.020608 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0203889 |
| CAVIN1 | caveolae associated protein 1 | -0.0202373 |
| RPL36 | ribosomal protein L36 | -0.0201497 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0200712 |
| RBM25 | RNA binding motif protein 25 | -0.0197379 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0196477 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0193695 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0192055 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0191488 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0190853 |
| S100A9 | S100 calcium binding protein A9 | -0.0187381 |
| RPLP1 | ribosomal protein, large, P1 | -0.0186391 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0185337 |
| RPL28 | ribosomal protein L28 | -0.0184728 |
| TXNIP | thioredoxin interacting protein | -0.0184434 |
| IRF1 | interferon regulatory factor 1 | -0.0184251 |