| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Retinoic acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRIP1 | nuclear receptor interacting protein 1 | 0.12892 |
| TXNRD1 | thioredoxin reductase 1 | 0.10668 |
| SMAD3 | SMAD family member 3 | 0.0691427 |
| NRP2 | neuropilin 2 | 0.0681438 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0678543 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0674881 |
| RAI14 | retinoic acid induced 14 | 0.0654914 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0622017 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0607916 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0606116 |
| JAK1 | Janus kinase 1 | 0.0556934 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0550992 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0543179 |
| PTK2 | protein tyrosine kinase 2 | 0.0529608 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0524025 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0477242 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0476484 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0475721 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.046524 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0463193 |
| FTL | ferritin, light polypeptide | 0.0453399 |
| ATP13A3 | ATPase type 13A3 | 0.04481 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0446577 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0443495 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0409516 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0399896 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.039538 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0383521 |
| RTN4 | reticulon 4 | 0.0375051 |
| APP | amyloid beta (A4) precursor protein | 0.0374559 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0370723 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0362662 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0361723 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0358174 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0346231 |
| B2M | beta-2-microglobulin | 0.0335321 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.033418 |
| CTBP2 | C-terminal binding protein 2 | 0.0331491 |
| RND3 | Rho family GTPase 3 | 0.032879 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0326131 |
| MKI67 | marker of proliferation Ki-67 | 0.0323186 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.032076 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0319909 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0318843 |
| SEPTIN9 | septin 9 | 0.0317977 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0317057 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0315024 |
| TPM3 | tropomyosin 3 | 0.0311989 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0307732 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0307299 |
| ITGAV | integrin, alpha V | 0.0305972 |
| ANXA2 | annexin A2 | 0.0301246 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0301197 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.030069 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0299383 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0299136 |
| CDCP1 | CUB domain containing protein 1 | 0.0298304 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0298029 |
| XPO1 | exportin 1 | 0.0296878 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0296587 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0296488 |
| RHEB | Ras homolog enriched in brain | 0.0296006 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294498 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0294041 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293088 |
| PLK2 | polo-like kinase 2 | 0.0288322 |
| TGM2 | transglutaminase 2 | 0.0285678 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0285212 |
| CADM1 | cell adhesion molecule 1 | 0.0284496 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0281135 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0279578 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0277317 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0273417 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0273138 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0272806 |
| MAP1B | microtubule-associated protein 1B | 0.0272135 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0267899 |
| USP12 | ubiquitin specific peptidase 12 | 0.0267422 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0267002 |
| TFG | TRK-fused gene | 0.0266709 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0266663 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.026296 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0257691 |
| USP3 | ubiquitin specific peptidase 3 | 0.02575 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0257435 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.025681 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0255945 |
| DUSP5 | dual specificity phosphatase 5 | 0.0253865 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0253291 |
| RASA2 | RAS p21 protein activator 2 | 0.0251678 |
| ATF3 | activating transcription factor 3 | 0.0251233 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0249851 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246673 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0245542 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0243925 |
| OPTN | optineurin | 0.0242127 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0241764 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0240576 |
| HELZ | helicase with zinc finger | 0.0237984 |
| AAK1 | AP2 associated kinase 1 | 0.0237523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.261328 |
| GPC6 | glypican 6 | -0.209828 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0810611 |
| TMSB10 | thymosin beta 10 | -0.0787074 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0663822 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0633572 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0587321 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.052162 |
| CP | ceruloplasmin (ferroxidase) | -0.0518791 |
| RRBP1 | ribosome binding protein 1 | -0.0517832 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0516729 |
| POTEF | POTE ankyrin domain family, member F | -0.0500949 |
| SCFD2 | sec1 family domain containing 2 | -0.0418286 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0382167 |
| CTSD | cathepsin D | -0.0359523 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0353585 |
| RIGI | RNA sensor RIG-I | -0.0349072 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0346432 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0341097 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0338861 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0335268 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0321162 |
| HLA-B | major histocompatibility complex, class I, B | -0.0320451 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | -0.031521 |
| EXOC4 | exocyst complex component 4 | -0.0310864 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0309775 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304835 |
| PRKCA | protein kinase C, alpha | -0.0303206 |
| NDRG1 | N-myc downstream regulated 1 | -0.0296447 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0292634 |
| MT2A | metallothionein 2A | -0.0283907 |
| PUM3 | pumilio RNA binding family member 3 | -0.0281539 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0266984 |
| UBAP2 | ubiquitin associated protein 2 | -0.0259647 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0257715 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0256258 |
| INTS6 | integrator complex subunit 6 | -0.0255477 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.025331 |
| EHBP1 | EH domain binding protein 1 | -0.02473 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0246233 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0243956 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0241315 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0237137 |
| CUX1 | cut-like homeobox 1 | -0.0236603 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0235613 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0234331 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0228791 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0225278 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0224845 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0224728 |
| PMM2 | phosphomannomutase 2 | -0.0224588 |
| FAM107B | family with sequence similarity 107, member B | -0.0221107 |
| COL5A1 | collagen, type V, alpha 1 | -0.0217587 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0210724 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0210564 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0210266 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0209533 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0207171 |
| RPS21 | ribosomal protein S21 | -0.0206879 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0202058 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0201717 |
| MORF4L2 | mortality factor 4 like 2 | -0.020078 |
| PTH2R | parathyroid hormone 2 receptor | -0.019955 |
| APOL1 | apolipoprotein L, 1 | -0.019788 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0196146 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0195024 |
| PFN1 | profilin 1 | -0.0193583 |
| GNAS | GNAS complex locus | -0.0191929 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0191319 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0190809 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0190759 |
| ANXA4 | annexin A4 | -0.0188908 |
| MAP4 | microtubule-associated protein 4 | -0.0188606 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0188554 |
| PLSCR2 | phospholipid scramblase 2 | -0.0187887 |
| FSTL1 | follistatin-like 1 | -0.0186449 |
| GLIS3 | GLIS family zinc finger 3 | -0.0186167 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0186036 |
| NEK10 | NIMA-related kinase 10 | -0.0185519 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0185166 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0184506 |
| SEM1 | SEM1 26S proteasome subunit | -0.0183887 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0183307 |
| TMEM263 | transmembrane protein 263 | -0.0179299 |
| SURF4 | surfeit 4 | -0.0177095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0177051 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0176303 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0171676 |
| NUP98 | nucleoporin 98kDa | -0.0170537 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0169259 |
| LAMB3 | laminin, beta 3 | -0.0169193 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0168844 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0168497 |
| NABP1 | nucleic acid binding protein 1 | -0.0166675 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0166198 |
| CBX3 | chromobox homolog 3 | -0.0165557 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0164255 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0163161 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0161992 |
| TPM1 | tropomyosin 1 (alpha) | -0.0160502 |
