| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Retinoic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.0381836 |
| INTS6 | integrator complex subunit 6 | 0.0260839 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0190053 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0183532 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0156783 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0154994 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0149972 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0138154 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0137374 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.013686 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0135651 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0134817 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0131187 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0130652 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0129103 |
| PLSCR2 | phospholipid scramblase 2 | 0.012559 |
| STXBP4 | syntaxin binding protein 4 | 0.0124625 |
| KRT86 | keratin 86, type II | 0.0119687 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0118303 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0113701 |
| FAM219A | family with sequence similarity 219, member A | 0.0110221 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0109986 |
| VCL | vinculin | 0.0109589 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0109254 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0108192 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.0108109 |
| RCOR1 | REST corepressor 1 | 0.0104913 |
| FGB | fibrinogen beta chain | 0.0101432 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.00997944 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.00973432 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0095543 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.00937949 |
| NEK7 | NIMA-related kinase 7 | 0.00931395 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00913197 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00894202 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00892228 |
| PNN | pinin, desmosome associated protein | 0.00875664 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.00857443 |
| DENND5A | DENN/MADD domain containing 5A | 0.00850385 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00845626 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00839865 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00823562 |
| RBM33 | RNA binding motif protein 33 | 0.00813044 |
| FAM168A | family with sequence similarity 168, member A | 0.00811049 |
| JAK1 | Janus kinase 1 | 0.00800471 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00796586 |
| CCNY | cyclin Y | 0.00792655 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00770428 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00768751 |
| TUFT1 | tuftelin 1 | 0.00768061 |
| HOMER1 | homer scaffolding protein 1 | 0.00761118 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00760058 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00757357 |
| RYK | receptor-like tyrosine kinase | 0.00752361 |
| DENND1A | DENN/MADD domain containing 1A | 0.00747666 |
| FNIP1 | folliculin interacting protein 1 | 0.00745247 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00744592 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.00740158 |
| USP15 | ubiquitin specific peptidase 15 | 0.00734934 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00732392 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00730748 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00723369 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00721485 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00717431 |
| EFNA5 | ephrin-A5 | 0.00712971 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0069693 |
| POU2F1 | POU class 2 homeobox 1 | 0.00689654 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00687031 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00681798 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00681629 |
| NABP1 | nucleic acid binding protein 1 | 0.00680007 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00678641 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.00674293 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00669693 |
| NPTN | neuroplastin | 0.00668143 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.00667069 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.00665526 |
| ANKRD17 | ankyrin repeat domain 17 | 0.00665475 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00655961 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00648433 |
| ATF6 | activating transcription factor 6 | 0.00647479 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.00639661 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00638704 |
| AFDN | afadin, adherens junction formation factor | 0.00637835 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0063711 |
| FOXJ3 | forkhead box J3 | 0.00628941 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00625901 |
| SIK3 | SIK family kinase 3 | 0.0061917 |
| MCU | mitochondrial calcium uniporter | 0.00599057 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.00596889 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.00595584 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00591509 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00582805 |
| MED13L | mediator complex subunit 13-like | 0.00582755 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00579844 |
| MYO1E | myosin IE | 0.00578571 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.00578361 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00577231 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00576114 |
| STK4 | serine/threonine kinase 4 | 0.00573902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.210032 |
| RPL19 | ribosomal protein L19 | -0.150348 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.109671 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0783956 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0729661 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0672803 |
| PTMA | prothymosin, alpha | -0.065869 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0658245 |
| TMSB10 | thymosin beta 10 | -0.0494482 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0484204 |
| ASPH | aspartate beta-hydroxylase | -0.0476926 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0460754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0448734 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0442771 |
| RPL35A | ribosomal protein L35a | -0.0426731 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0370624 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0368079 |
| LASP1 | LIM and SH3 protein 1 | -0.0363084 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036301 |
| ACTG1 | actin gamma 1 | -0.0360229 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0355079 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0348015 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0321658 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.030084 |
| POTEF | POTE ankyrin domain family, member F | -0.0291286 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0290327 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0288562 |
| KRT19 | keratin 19, type I | -0.0285218 |
| TMSB4X | thymosin beta 4, X-linked | -0.027833 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0273358 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0260745 |
| DSTN | destrin (actin depolymerizing factor) | -0.0258974 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.025856 |
| S100A9 | S100 calcium binding protein A9 | -0.0254036 |
| ENO1 | enolase 1, (alpha) | -0.0249108 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.024855 |
| RPS6 | ribosomal protein S6 | -0.0242765 |
| CCND1 | cyclin D1 | -0.0238677 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0236276 |
| FADS2 | fatty acid desaturase 2 | -0.0235629 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0234358 |
| CCNI | cyclin I | -0.0233812 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0232898 |
| PKM | pyruvate kinase, muscle | -0.0232061 |
| RPL12 | ribosomal protein L12 | -0.023095 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0230312 |
| VMP1 | vacuole membrane protein 1 | -0.0227991 |
| RPS19 | ribosomal protein S19 | -0.02277 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0224201 |
| S100A14 | S100 calcium binding protein A14 | -0.0223646 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0219668 |
| TPM4 | tropomyosin 4 | -0.0216683 |
| B2M | beta-2-microglobulin | -0.0215998 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0212679 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0212241 |
| GNAS | GNAS complex locus | -0.0206246 |
| RPL8 | ribosomal protein L8 | -0.0205258 |
| RPS3 | ribosomal protein S3 | -0.0205031 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200431 |
| RPL35 | ribosomal protein L35 | -0.0200397 |
| OSMR | oncostatin M receptor | -0.0194546 |
| S100A8 | S100 calcium binding protein A8 | -0.0193904 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0193336 |
| NDRG1 | N-myc downstream regulated 1 | -0.0193258 |
| AHNAK | AHNAK nucleoprotein | -0.0192403 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0190562 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0189703 |
| S100A6 | S100 calcium binding protein A6 | -0.0189418 |
| RPLP1 | ribosomal protein, large, P1 | -0.0188957 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0187471 |
| LDHA | lactate dehydrogenase A | -0.0187235 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0186112 |
| ZNF652 | zinc finger protein 652 | -0.0184764 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0184296 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0184287 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0184196 |
| CBX3 | chromobox homolog 3 | -0.0183819 |
| LMNA | lamin A/C | -0.0182797 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0182723 |
| TMEM123 | transmembrane protein 123 | -0.018147 |
| TMC5 | transmembrane channel-like 5 | -0.0181208 |
| INSIG1 | insulin induced gene 1 | -0.0181161 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0178065 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0178038 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0177701 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0177459 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0177144 |
| SMIM14 | small integral membrane protein 14 | -0.0174936 |
| DSPP | dentin sialophosphoprotein | -0.017388 |
| TMEM165 | transmembrane protein 165 | -0.0172392 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0171345 |
| DUSP4 | dual specificity phosphatase 4 | -0.016961 |
| RPL28 | ribosomal protein L28 | -0.0169136 |
| PFN1 | profilin 1 | -0.0168357 |
| FASN | fatty acid synthase | -0.0166205 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0164148 |
| BPTF | bromodomain PHD finger transcription factor | -0.0163775 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0161011 |
| TMEM45B | transmembrane protein 45B | -0.0159572 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0158528 |