| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Retinoic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.176722 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.120659 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.118003 |
| FAM13A | family with sequence similarity 13, member A | 0.098364 |
| PTK2 | protein tyrosine kinase 2 | 0.0895293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0876712 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0869809 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.080628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0791073 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0785492 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0760043 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0750892 |
| MYO10 | myosin X | 0.0680836 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0648043 |
| RUNX1 | runt-related transcription factor 1 | 0.0646554 |
| ENO1 | enolase 1, (alpha) | 0.0637254 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.059895 |
| RRM2 | ribonucleotide reductase M2 | 0.0593937 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.058549 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.058353 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0582881 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0575012 |
| MT2A | metallothionein 2A | 0.0571608 |
| SEPTIN9 | septin 9 | 0.0566879 |
| ADM | adrenomedullin | 0.0521281 |
| CALR | calreticulin | 0.0510048 |
| WWOX | WW domain containing oxidoreductase | 0.0508415 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0505363 |
| MSN | moesin | 0.0502513 |
| FLNB | filamin B, beta | 0.050155 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0490117 |
| DST | dystonin | 0.0489438 |
| AXL | AXL receptor tyrosine kinase | 0.0488137 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.048751 |
| SMAD3 | SMAD family member 3 | 0.0485726 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0471251 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0467082 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0466182 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0466182 |
| MAP1B | microtubule-associated protein 1B | 0.0458414 |
| NAV1 | neuron navigator 1 | 0.0456206 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0452231 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.044744 |
| ANKRD11 | ankyrin repeat domain 11 | 0.044628 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0439729 |
| TGFB1 | transforming growth factor, beta 1 | 0.0434646 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0433135 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0428705 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0427721 |
| INTS6 | integrator complex subunit 6 | 0.042593 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0422673 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0400348 |
| DTNA | dystrobrevin, alpha | 0.0399523 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0389764 |
| RCOR1 | REST corepressor 1 | 0.0387538 |
| TNS1 | tensin 1 | 0.0387174 |
| RPS6 | ribosomal protein S6 | 0.0381655 |
| RNF145 | ring finger protein 145 | 0.038158 |
| RPS8 | ribosomal protein S8 | 0.0374896 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0369761 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0364414 |
| MYO1B | myosin IB | 0.035898 |
| FTL | ferritin, light polypeptide | 0.0355513 |
| GRAMD1B | GRAM domain containing 1B | 0.0353821 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0352944 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0345738 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0344238 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0343153 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0343099 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0341365 |
| RNF24 | ring finger protein 24 | 0.0339182 |
| ZNF638 | zinc finger protein 638 | 0.0336862 |
| RAI14 | retinoic acid induced 14 | 0.0335743 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0333938 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0333254 |
| PKM | pyruvate kinase, muscle | 0.0331088 |
| PTMA | prothymosin, alpha | 0.0324775 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0324126 |
| EFNA5 | ephrin-A5 | 0.0323903 |
| B2M | beta-2-microglobulin | 0.0319859 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0319577 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0317691 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0313954 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0309823 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0308809 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0306281 |
| KIAA1217 | KIAA1217 | 0.0302817 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0302349 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0302129 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0299216 |
| TPM3 | tropomyosin 3 | 0.0298889 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.029766 |
| RYBP | RING1 and YY1 binding protein | 0.0297413 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0287135 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0287058 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0286587 |
| MCL1 | myeloid cell leukemia 1 | 0.0286376 |
| RPS3 | ribosomal protein S3 | 0.0286366 |
| HELZ | helicase with zinc finger | 0.0282729 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.3219 |
| GLIS3 | GLIS family zinc finger 3 | -0.0944112 |
| CDH13 | cadherin 13 | -0.0838227 |
| HMGA2 | high mobility group AT-hook 2 | -0.0779101 |
| LOX | lysyl oxidase | -0.0754672 |
| VIM | vimentin | -0.0697873 |
| TNNC1 | troponin C type 1 (slow) | -0.0695994 |
| IGF2 | insulin-like growth factor 2 | -0.0680219 |
| TENM2 | teneurin transmembrane protein 2 | -0.0630498 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0548831 |
| CD44 | CD44 molecule (Indian blood group) | -0.0545987 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0532078 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0487422 |
| SBF2 | SET binding factor 2 | -0.0477697 |
| OSMR | oncostatin M receptor | -0.0473666 |
| RRBP1 | ribosome binding protein 1 | -0.0444715 |
| EGR1 | early growth response 1 | -0.0423735 |
| TMSB10 | thymosin beta 10 | -0.0410827 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0399645 |
| LAMB3 | laminin, beta 3 | -0.0399026 |
| FMN1 | formin 1 | -0.0388351 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0360295 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0356103 |
| OGA | O-GlcNAcase | -0.0344196 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0338421 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0338112 |
| HDLBP | high density lipoprotein binding protein | -0.0333552 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.032825 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0325597 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0319199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0315865 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.03127 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0303936 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.03023 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293798 |
| NDRG1 | N-myc downstream regulated 1 | -0.0288461 |
| FSTL1 | follistatin-like 1 | -0.0286583 |
| RTN4 | reticulon 4 | -0.0285712 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0279972 |
| VCL | vinculin | -0.0278721 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0276789 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0276502 |
| AHNAK | AHNAK nucleoprotein | -0.0269672 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0266046 |
| INHBA | inhibin, beta A | -0.0263896 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0262604 |
| TMEM263 | transmembrane protein 263 | -0.0262432 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0262384 |
| ARF1 | ADP-ribosylation factor 1 | -0.0260748 |
| ZNF217 | zinc finger protein 217 | -0.0253114 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0250436 |
| SGO2 | shugoshin 2 | -0.0249637 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0245481 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0242265 |
| CAVIN1 | caveolae associated protein 1 | -0.0240734 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0236873 |
| CD109 | CD109 molecule | -0.0235803 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0232383 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0229677 |
| DUSP6 | dual specificity phosphatase 6 | -0.0228856 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0228842 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0228626 |
| CANX | calnexin | -0.0227408 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.022589 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0224607 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0223457 |
| THBS1 | thrombospondin 1 | -0.0222865 |
| RNF149 | ring finger protein 149 | -0.0219598 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0217827 |
| NF1 | neurofibromin 1 | -0.0216905 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0216524 |
| EPN2 | epsin 2 | -0.0216449 |
| ACTG1 | actin gamma 1 | -0.0216024 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0215773 |
| GOLT1B | golgi transport 1B | -0.0214741 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0213909 |
| SEC24D | SEC24 family member D | -0.0213486 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0213276 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0209867 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0209824 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0208416 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0207927 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0206647 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0202598 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0197767 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0197708 |
| TMEM165 | transmembrane protein 165 | -0.0197101 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0197002 |
| PCBP3 | poly(rC) binding protein 3 | -0.0196988 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0195935 |
| CEP95 | centrosomal protein 95kDa | -0.0192572 |
| PDE10A | phosphodiesterase 10A | -0.0190073 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0189816 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0189219 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0188891 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.018833 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0187233 |
| WDR26 | WD repeat domain 26 | -0.0186177 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0185819 |
| CDCP1 | CUB domain containing protein 1 | -0.0184968 |
