| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Retinoic acid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.184947 |
| DST | dystonin | 0.152318 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.111241 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0958705 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0869791 |
| TP63 | tumor protein p63 | 0.085619 |
| RAD51B | RAD51 paralog B | 0.0854328 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0839552 |
| CADM2 | cell adhesion molecule 2 | 0.0811413 |
| VCL | vinculin | 0.0727096 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0675023 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0671028 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0665496 |
| RUNX1 | runt-related transcription factor 1 | 0.0639432 |
| PRELID2 | PRELI domain containing 2 | 0.0635963 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0625574 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0620554 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0598065 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0559645 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0534872 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0525731 |
| EXOC4 | exocyst complex component 4 | 0.0523114 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0521727 |
| CD44 | CD44 molecule (Indian blood group) | 0.0509763 |
| SMYD3 | SET and MYND domain containing 3 | 0.0495548 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0485634 |
| CDK6 | cyclin-dependent kinase 6 | 0.0475875 |
| DNER | delta/notch-like EGF repeat containing | 0.0466029 |
| CMIP | c-Maf inducing protein | 0.0455706 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0448179 |
| MT2A | metallothionein 2A | 0.0444773 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.042818 |
| DPH6 | diphthamine biosynthesis 6 | 0.0423899 |
| TNS3 | tensin 3 | 0.0403894 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0386875 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.038353 |
| H1-0 | H1.0 linker histone | 0.0381288 |
| CEP128 | centrosomal protein 128kDa | 0.03716 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0367961 |
| SMAD3 | SMAD family member 3 | 0.0362465 |
| FMNL2 | formin-like 2 | 0.0361007 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0360362 |
| HDAC9 | histone deacetylase 9 | 0.035396 |
| SVIL | supervillin | 0.0348331 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0339626 |
| RTTN | rotatin | 0.0336746 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.033447 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0333974 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0333547 |
| PLK2 | polo-like kinase 2 | 0.0323562 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.03215 |
| EPHA4 | EPH receptor A4 | 0.0318983 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0318607 |
| ENO1 | enolase 1, (alpha) | 0.0316424 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0312393 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0307806 |
| VEGFC | vascular endothelial growth factor C | 0.0307661 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.030596 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0297234 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0281996 |
| TPRG1 | tumor protein p63 regulated 1 | 0.028106 |
| RNF213 | ring finger protein 213 | 0.0279369 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0278287 |
| ECE1 | endothelin converting enzyme 1 | 0.0273965 |
| SQSTM1 | sequestosome 1 | 0.0270998 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0269757 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0264482 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0264168 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0263658 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0263015 |
| PRKCE | protein kinase C, epsilon | 0.0261609 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0259559 |
| TBC1D5 | TBC1 domain family, member 5 | 0.025773 |
| HELLS | helicase, lymphoid-specific | 0.0256131 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.025559 |
| SP100 | SP100 nuclear antigen | 0.0255308 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0255255 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0241805 |
| DEK | DEK proto-oncogene | 0.02417 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0241292 |
| NEBL | nebulette | 0.0241073 |
| USP11 | ubiquitin specific peptidase 11 | 0.023692 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0234106 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0232077 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0230963 |
| DIAPH3 | diaphanous-related formin 3 | 0.0230039 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0228593 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0225326 |
| F2R | coagulation factor II (thrombin) receptor | 0.0224757 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.022348 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0222755 |
| TGM2 | transglutaminase 2 | 0.0222632 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0220144 |
| UTRN | utrophin | 0.0218664 |
| FOXP1 | forkhead box P1 | 0.0218539 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0216125 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0206096 |
| IPO9 | importin 9 | 0.0205777 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0201903 |
| DIAPH1 | diaphanous-related formin 1 | 0.0201018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.187604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.147408 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139223 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.116355 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113886 |
| PTMA | prothymosin, alpha | -0.109916 |
| TMSB4X | thymosin beta 4, X-linked | -0.0916063 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0885507 |
| TXNRD1 | thioredoxin reductase 1 | -0.0825059 |
| TMSB10 | thymosin beta 10 | -0.0820415 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0784191 |
| RPL26 | ribosomal protein L26 | -0.0774764 |
| RAI1 | retinoic acid induced 1 | -0.0772475 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0771554 |
| SPAG9 | sperm associated antigen 9 | -0.0739747 |
| RPL35A | ribosomal protein L35a | -0.0639161 |
| RPS6 | ribosomal protein S6 | -0.0624817 |
| RPS8 | ribosomal protein S8 | -0.062065 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0620565 |
| CANX | calnexin | -0.0617018 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0590214 |
| RPL12 | ribosomal protein L12 | -0.0581258 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0575225 |
| USP34 | ubiquitin specific peptidase 34 | -0.0573498 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0562105 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0550784 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0530462 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0510733 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0508153 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0494479 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0476267 |
| RPS24 | ribosomal protein S24 | -0.046252 |
| RPL36A | ribosomal protein L36a | -0.0457186 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0451431 |
| RPL37A | ribosomal protein L37a | -0.044405 |
| TMEM41B | transmembrane protein 41B | -0.0443794 |
| RPS2 | ribosomal protein S2 | -0.0441246 |
| RPL34 | ribosomal protein L34 | -0.0436091 |
| NUP58 | nucleoporin 58 | -0.0432796 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0416311 |
| ZNF217 | zinc finger protein 217 | -0.0411772 |
| RPS3 | ribosomal protein S3 | -0.0409201 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0400557 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.039889 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0390017 |
| MT1X | metallothionein 1X | -0.0387991 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0384436 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0382026 |
| RPL38 | ribosomal protein L38 | -0.0375566 |
| RPS27A | ribosomal protein S27a | -0.0373673 |
| CENPF | centromere protein F, 350/400kDa | -0.0372577 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0366937 |
| HLA-B | major histocompatibility complex, class I, B | -0.0366446 |
| RPL23 | ribosomal protein L23 | -0.0365713 |
| KLF6 | Kruppel-like factor 6 | -0.0360345 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0351241 |
| RPL37 | ribosomal protein L37 | -0.0348294 |
| RPS21 | ribosomal protein S21 | -0.0342131 |
| RPL31 | ribosomal protein L31 | -0.0337238 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033689 |
| RPS23 | ribosomal protein S23 | -0.0336405 |
| RPS19 | ribosomal protein S19 | -0.0333702 |
| SET | SET nuclear proto-oncogene | -0.0329996 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329676 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0329165 |
| RBM39 | RNA binding motif protein 39 | -0.0325921 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0325642 |
| RPS13 | ribosomal protein S13 | -0.0324576 |
| YBX3 | Y box binding protein 3 | -0.0308993 |
| RPS25 | ribosomal protein S25 | -0.0308165 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0305155 |
| POTEF | POTE ankyrin domain family, member F | -0.0302447 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0300958 |
| RACK1 | receptor for activated C kinase 1 | -0.0294244 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.029369 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0289614 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0287751 |
| RPL18 | ribosomal protein L18 | -0.0287674 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0287012 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0286111 |
| UPP1 | uridine phosphorylase 1 | -0.0285215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0283859 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0280605 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0274428 |
| SEC24A | SEC24 family member A | -0.0272587 |
| TXNIP | thioredoxin interacting protein | -0.0268708 |
| RPS12 | ribosomal protein S12 | -0.0265753 |
| RPL7A | ribosomal protein L7a | -0.0264521 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0263513 |
| WDR45B | WD repeat domain 45B | -0.0262413 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0260737 |
| RPL9 | ribosomal protein L9 | -0.0258895 |
| AHNAK | AHNAK nucleoprotein | -0.0257383 |
| GOLT1B | golgi transport 1B | -0.0256251 |
| RPL19 | ribosomal protein L19 | -0.025538 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0254235 |
| UBC | ubiquitin C | -0.0250926 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.024907 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0248515 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0247639 |