| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Retinoic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.144833 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.106537 |
| UBC | ubiquitin C | 0.104517 |
| EGFR | epidermal growth factor receptor | 0.0841648 |
| INTS6 | integrator complex subunit 6 | 0.0828657 |
| MYOF | myoferlin | 0.0805719 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0796026 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0787389 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0749331 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0646461 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0609979 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0608211 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0566826 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0550746 |
| RNF213 | ring finger protein 213 | 0.0542525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0529534 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0521095 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0516453 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0514594 |
| SCEL | sciellin | 0.0485612 |
| RPS27A | ribosomal protein S27a | 0.0434778 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0426875 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.042686 |
| PRKCA | protein kinase C, alpha | 0.0424269 |
| SMAD3 | SMAD family member 3 | 0.042031 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0405902 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0394686 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0384563 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0380653 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0371295 |
| KRT7 | keratin 7, type II | 0.0368418 |
| HOMER1 | homer scaffolding protein 1 | 0.0360447 |
| SMYD3 | SET and MYND domain containing 3 | 0.0351116 |
| PCBP2 | poly(rC) binding protein 2 | 0.0345986 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0339491 |
| TMSB10 | thymosin beta 10 | 0.0331542 |
| MCL1 | myeloid cell leukemia 1 | 0.0330337 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.032185 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0320026 |
| RPS3 | ribosomal protein S3 | 0.032001 |
| PTMA | prothymosin, alpha | 0.0318692 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.031376 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0305625 |
| AHNAK | AHNAK nucleoprotein | 0.0288922 |
| FLNB | filamin B, beta | 0.0286788 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0286109 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0281342 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0281303 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0278578 |
| IFI44L | interferon-induced protein 44-like | 0.0275395 |
| SP100 | SP100 nuclear antigen | 0.0273981 |
| CMIP | c-Maf inducing protein | 0.0273944 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0273259 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0272701 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0272106 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0270524 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268964 |
| DST | dystonin | 0.0262205 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0261409 |
| GPHN | gephyrin | 0.0259025 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0258384 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0257926 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0254984 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.025288 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0252635 |
| FUS | FUS RNA binding protein | 0.0252259 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0252071 |
| CTBP2 | C-terminal binding protein 2 | 0.024905 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0249033 |
| ENO1 | enolase 1, (alpha) | 0.0247265 |
| B2M | beta-2-microglobulin | 0.0245836 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0243948 |
| MLPH | melanophilin | 0.0242372 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0241026 |
| PTK2 | protein tyrosine kinase 2 | 0.0240973 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0232376 |
| RAD51B | RAD51 paralog B | 0.0231466 |
| PKM | pyruvate kinase, muscle | 0.0230737 |
| IFI44 | interferon-induced protein 44 | 0.0227728 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0226181 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0224318 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0221236 |
| APP | amyloid beta (A4) precursor protein | 0.0216236 |
| KRT8 | keratin 8, type II | 0.0215143 |
| FNIP1 | folliculin interacting protein 1 | 0.021269 |
| SUMF1 | sulfatase modifying factor 1 | 0.0210479 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.021031 |
| MX1 | MX dynamin-like GTPase 1 | 0.0210167 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0209508 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0208382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0206339 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0204379 |
| TNS3 | tensin 3 | 0.0201069 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0200467 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0200201 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0200053 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0198658 |
| CTTN | cortactin | 0.0196961 |
| WWOX | WW domain containing oxidoreductase | 0.0195735 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0195434 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225414 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.200597 |
| TXNRD1 | thioredoxin reductase 1 | -0.168583 |
| CES1 | carboxylesterase 1 | -0.111552 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0988179 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0914459 |
| MT2A | metallothionein 2A | -0.0820906 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0763451 |
| OSMR | oncostatin M receptor | -0.0579243 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0569282 |
| HDLBP | high density lipoprotein binding protein | -0.0554931 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0541895 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0537196 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0517318 |
| TMEM165 | transmembrane protein 165 | -0.0506004 |
| H1-0 | H1.0 linker histone | -0.0502641 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0484904 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0479435 |
| EGR1 | early growth response 1 | -0.0475097 |
| FTL | ferritin, light polypeptide | -0.0467748 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0436668 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0427065 |
| GOLGB1 | golgin B1 | -0.0423934 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0419319 |
| TES | testin LIM domain protein | -0.0412727 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0396927 |
| NGLY1 | N-glycanase 1 | -0.0396659 |
| NPC1 | Niemann-Pick disease, type C1 | -0.039163 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0370916 |
| SPAG9 | sperm associated antigen 9 | -0.036909 |
| MGAT4C | MGAT4 family, member C | -0.0365968 |
| CANX | calnexin | -0.0365294 |
| NDRG1 | N-myc downstream regulated 1 | -0.0364968 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0359909 |
| GM2A | GM2 ganglioside activator | -0.0358472 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352495 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0345057 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.034329 |
| RPS6 | ribosomal protein S6 | -0.0341885 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0337511 |
| LAMA4 | laminin, alpha 4 | -0.0329561 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0328983 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0325607 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0321433 |
| MKI67 | marker of proliferation Ki-67 | -0.0318142 |
| RPL35A | ribosomal protein L35a | -0.0313491 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0304139 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0302604 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289999 |
| ABLIM1 | actin binding LIM protein 1 | -0.0289208 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281031 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.028076 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0278511 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0276398 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0275202 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0272574 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0272097 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0271724 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0262992 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0262063 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.026198 |
| WASF2 | WAS protein family, member 2 | -0.0261444 |
| ANXA2 | annexin A2 | -0.0260231 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0259801 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0259775 |
| MYO1B | myosin IB | -0.0256634 |
| MORF4L2 | mortality factor 4 like 2 | -0.0253204 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0252179 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0251678 |
| LAMB3 | laminin, beta 3 | -0.0250153 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0248011 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0247996 |
| WDR45B | WD repeat domain 45B | -0.0245371 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0244689 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0243381 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0241649 |
| RTN4 | reticulon 4 | -0.0241639 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0241613 |
| CPE | carboxypeptidase E | -0.0239413 |
| RAD21 | RAD21 homolog (S. pombe) | -0.02382 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0237481 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0233614 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0233176 |
| KMT5B | lysine methyltransferase 5B | -0.0229048 |
| CCNK | cyclin K | -0.0227651 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0227325 |
| RNF149 | ring finger protein 149 | -0.022715 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022658 |
| SEPTIN2 | septin 2 | -0.0226081 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0223007 |
| METTL9 | methyltransferase like 9 | -0.022277 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0220317 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0218782 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0218728 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0217078 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0215114 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0211813 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0210147 |
| HM13 | histocompatibility (minor) 13 | -0.0208113 |
| FRY | furry homolog (Drosophila) | -0.0207765 |
