| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Retinoic acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.18673 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.156172 |
| LMO7 | LIM domain 7 | 0.121487 |
| EGFR | epidermal growth factor receptor | 0.0981767 |
| DSCAM | Down syndrome cell adhesion molecule | 0.095349 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0918743 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.091733 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0841224 |
| SLTM | SAFB-like, transcription modulator | 0.0817551 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.077157 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.07268 |
| NDRG1 | N-myc downstream regulated 1 | 0.0722772 |
| RAD51B | RAD51 paralog B | 0.0702097 |
| FNIP1 | folliculin interacting protein 1 | 0.0670197 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0666701 |
| TJP1 | tight junction protein 1 | 0.0653004 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0639492 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.054787 |
| MYO1E | myosin IE | 0.0545843 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0542454 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0539428 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0538267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0536485 |
| EZR | ezrin | 0.0534731 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0532832 |
| PALLD | palladin, cytoskeletal associated protein | 0.0530698 |
| ATXN1 | ataxin 1 | 0.0518456 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0517912 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0513801 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0513192 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0506011 |
| SMAD2 | SMAD family member 2 | 0.0505667 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0501555 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0497122 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0493606 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0493003 |
| ANO6 | anoctamin 6 | 0.0486262 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.048626 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0484978 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0481649 |
| FLNB | filamin B, beta | 0.0477124 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0474868 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0471177 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0467539 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0462442 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0461601 |
| VCL | vinculin | 0.0460843 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.045739 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0454878 |
| MYOF | myoferlin | 0.0454084 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0453666 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.04431 |
| FRY | furry homolog (Drosophila) | 0.0438192 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0436738 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0431706 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0429583 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0427524 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0421521 |
| SNX9 | sorting nexin 9 | 0.0413251 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0412359 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0411955 |
| STEAP4 | STEAP family member 4 | 0.0410672 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0410444 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0407807 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0405173 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0404234 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0402519 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0401712 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0401031 |
| LIMA1 | LIM domain and actin binding 1 | 0.0394612 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0392189 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0382448 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0380245 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0378038 |
| APP | amyloid beta (A4) precursor protein | 0.0377636 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0376975 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.036852 |
| KIAA1328 | KIAA1328 | 0.0366936 |
| WDR26 | WD repeat domain 26 | 0.036645 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.036487 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0363495 |
| RBM15 | RNA binding motif protein 15 | 0.036266 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0360806 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0359258 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0358068 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.035203 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0351447 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0349157 |
| TOP1 | topoisomerase (DNA) I | 0.0346906 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.034344 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.034069 |
| TUT7 | terminal uridylyl transferase 7 | 0.0339989 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0338495 |
| SECISBP2L | SECIS binding protein 2-like | 0.0336967 |
| FOXP1 | forkhead box P1 | 0.0336434 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0334261 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0333303 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0332704 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.033132 |
| SVIL | supervillin | 0.0328317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.123776 |
| COL6A3 | collagen, type VI, alpha 3 | -0.108734 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.101868 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0991724 |
| FN1 | fibronectin 1 | -0.0963942 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0898362 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0855474 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0836596 |
| ACTG1 | actin gamma 1 | -0.0750232 |
| AHNAK | AHNAK nucleoprotein | -0.072338 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0713449 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0697606 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.067488 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0647256 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.064091 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0631568 |
| HOMER1 | homer scaffolding protein 1 | -0.0612363 |
| ABHD17C | abhydrolase domain containing 17C | -0.060435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0587217 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0583931 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0580425 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0575442 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0566748 |
| PKM | pyruvate kinase, muscle | -0.05611 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0549815 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.054801 |
| HLA-B | major histocompatibility complex, class I, B | -0.0546315 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0532545 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0530281 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.052182 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0521492 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0506153 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0502761 |
| RTN4 | reticulon 4 | -0.0500309 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0497818 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0497514 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0489307 |
| COL5A1 | collagen, type V, alpha 1 | -0.0481725 |
| DENND4A | DENN/MADD domain containing 4A | -0.048164 |
| MED13L | mediator complex subunit 13-like | -0.0481491 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0473463 |
| MEF2A | myocyte enhancer factor 2A | -0.0472739 |
| ANTXR2 | anthrax toxin receptor 2 | -0.045504 |
| CCNY | cyclin Y | -0.0454307 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0452773 |
| VMP1 | vacuole membrane protein 1 | -0.0449016 |
| CANX | calnexin | -0.0448829 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0442108 |
| TMEM87A | transmembrane protein 87A | -0.0441048 |
| FRMD5 | FERM domain containing 5 | -0.0441044 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0436442 |
| RORA | RAR-related orphan receptor A | -0.0435869 |
| RBM47 | RNA binding motif protein 47 | -0.0433909 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.043102 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | -0.0428179 |
| MMP1 | matrix metallopeptidase 1 | -0.0425698 |
| TPM4 | tropomyosin 4 | -0.0421117 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0417953 |
| RPL27A | ribosomal protein L27a | -0.0412433 |
| PGK1 | phosphoglycerate kinase 1 | -0.0410689 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0410149 |
| HPCAL1 | hippocalcin-like 1 | -0.0407019 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0403085 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0400995 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.039811 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0395165 |
| SDC4 | syndecan 4 | -0.0393186 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0391805 |
| RASA2 | RAS p21 protein activator 2 | -0.0387765 |
| SPPL3 | signal peptide peptidase like 3 | -0.038603 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0385692 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0381964 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0375638 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0374948 |
| GLIS3 | GLIS family zinc finger 3 | -0.0374806 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0370967 |
| CD2AP | CD2-associated protein | -0.0368987 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0368453 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0368212 |
| PARD3 | par-3 family cell polarity regulator | -0.0366116 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0364474 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.036316 |
| SBF2 | SET binding factor 2 | -0.036263 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0361426 |
| CDH13 | cadherin 13 | -0.035605 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0355298 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0350622 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0349282 |
| SPAG9 | sperm associated antigen 9 | -0.0347731 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0346611 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0345533 |
| FAM13A | family with sequence similarity 13, member A | -0.034408 |
| MIDN | midnolin | -0.034133 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0341019 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0337433 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0336837 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0336415 |
| EXOC1 | exocyst complex component 1 | -0.0335118 |
| VEGFA | vascular endothelial growth factor A | -0.0334162 |
| TPR | translocated promoter region, nuclear basket protein | -0.0333963 |
