| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Retinoic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.234343 |
| PDLIM5 | PDZ and LIM domain 5 | 0.141 |
| KYNU | kynureninase | 0.138847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.110978 |
| MYOF | myoferlin | 0.0963469 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.096151 |
| ASPH | aspartate beta-hydroxylase | 0.0944568 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0928651 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0925417 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0915211 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0811958 |
| MCL1 | myeloid cell leukemia 1 | 0.0792313 |
| PDE10A | phosphodiesterase 10A | 0.0791648 |
| GRAMD1B | GRAM domain containing 1B | 0.0741462 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0739206 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0688547 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0658041 |
| CD109 | CD109 molecule | 0.0632451 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0614893 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0608663 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0598659 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0561119 |
| CENPF | centromere protein F, 350/400kDa | 0.0556209 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0538722 |
| VCL | vinculin | 0.053523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0533315 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.052345 |
| PCBP2 | poly(rC) binding protein 2 | 0.0523336 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0523322 |
| COL5A2 | collagen, type V, alpha 2 | 0.0517961 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.050965 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0507093 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0504246 |
| MSN | moesin | 0.0501114 |
| LDHA | lactate dehydrogenase A | 0.0499902 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0495054 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0490691 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0488093 |
| DST | dystonin | 0.0481271 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0470892 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.045877 |
| PKM | pyruvate kinase, muscle | 0.045081 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0435081 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0421965 |
| EZR | ezrin | 0.0420784 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0410159 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0409758 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0402196 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0401725 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0400872 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0397884 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0383922 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0380742 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0374583 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0371074 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0366907 |
| INTS6 | integrator complex subunit 6 | 0.036159 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0357631 |
| RAD51B | RAD51 paralog B | 0.0355173 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.035342 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351808 |
| TPM3 | tropomyosin 3 | 0.0349662 |
| MKI67 | marker of proliferation Ki-67 | 0.0344526 |
| BMP6 | bone morphogenetic protein 6 | 0.0338061 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0336262 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0328498 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0327684 |
| SET | SET nuclear proto-oncogene | 0.0313292 |
| EPHA4 | EPH receptor A4 | 0.0307198 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0306627 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0299506 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0296432 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0293539 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0293448 |
| SMAD2 | SMAD family member 2 | 0.0293374 |
| CTBP2 | C-terminal binding protein 2 | 0.0292257 |
| PTEN | phosphatase and tensin homolog | 0.0291495 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0291295 |
| ENO1 | enolase 1, (alpha) | 0.0291032 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284732 |
| NTN4 | netrin 4 | 0.028432 |
| COPA | coatomer protein complex, subunit alpha | 0.0284223 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284015 |
| ANXA2 | annexin A2 | 0.0282964 |
| SQSTM1 | sequestosome 1 | 0.0282852 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0282566 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0282405 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0280362 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.028029 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0278788 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0277872 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0274684 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0273655 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0273026 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0272318 |
| RPS2 | ribosomal protein S2 | 0.0271837 |
| RPL3 | ribosomal protein L3 | 0.0270928 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0270146 |
| ATXN1 | ataxin 1 | 0.026349 |
| B2M | beta-2-microglobulin | 0.0261168 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.176782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134154 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.120207 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.095914 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0846361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.082748 |
| PTMA | prothymosin, alpha | -0.0740326 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0702647 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0671535 |
| TMSB10 | thymosin beta 10 | -0.0626468 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0623821 |
| RPS24 | ribosomal protein S24 | -0.0581844 |
| SMYD3 | SET and MYND domain containing 3 | -0.0565563 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.055208 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0496048 |
| NCKAP5 | NCK-associated protein 5 | -0.0485138 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0453328 |
| RPL34 | ribosomal protein L34 | -0.0450055 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0404237 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0401948 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0397672 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0395463 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.038226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381102 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0379756 |
| OGA | O-GlcNAcase | -0.0370775 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0369487 |
| RPL26 | ribosomal protein L26 | -0.0366651 |
| RPS21 | ribosomal protein S21 | -0.0360319 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0356529 |
| HLA-B | major histocompatibility complex, class I, B | -0.0349473 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0322165 |
| CTSL | cathepsin L | -0.0321787 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0320458 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0318521 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0312651 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0309074 |
| RPL12 | ribosomal protein L12 | -0.0301543 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0298315 |
| CANX | calnexin | -0.0297854 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0296775 |
| RPL35A | ribosomal protein L35a | -0.0291556 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0288938 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0288009 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0280746 |
| RPL23 | ribosomal protein L23 | -0.026749 |
| RPS19 | ribosomal protein S19 | -0.0263703 |
| CDH13 | cadherin 13 | -0.0261143 |
| OSMR | oncostatin M receptor | -0.0257644 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0256664 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0253565 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0253117 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0251572 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0247277 |
| RAI1 | retinoic acid induced 1 | -0.0245199 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0245002 |
| PTGR1 | prostaglandin reductase 1 | -0.0231766 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0230058 |
| PCBP3 | poly(rC) binding protein 3 | -0.0229222 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0227244 |
| RPL36A | ribosomal protein L36a | -0.0225955 |
| KIAA0825 | KIAA0825 | -0.0219276 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0217951 |
| STC1 | stanniocalcin 1 | -0.0217671 |
| LIN7A | lin-7 homolog A (C. elegans) | -0.0215157 |
| TMSB4X | thymosin beta 4, X-linked | -0.0214623 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0214014 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.02133 |
| INHBA | inhibin, beta A | -0.0213001 |
| FOXC1 | forkhead box C1 | -0.021166 |
| RPL38 | ribosomal protein L38 | -0.0210196 |
| NEDD1 | neural precursor cell expressed, developmentally down-regulated 1 | -0.0204742 |
| AHNAK | AHNAK nucleoprotein | -0.0202614 |
| CRLF2 | cytokine receptor-like factor 2 | -0.0200596 |
| IER3 | immediate early response 3 | -0.0197128 |
| SRPK2 | SRSF protein kinase 2 | -0.0196842 |
| NF1 | neurofibromin 1 | -0.0196344 |
| RPS16 | ribosomal protein S16 | -0.0195075 |
| RBM39 | RNA binding motif protein 39 | -0.0193535 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0190942 |
| PRSS23 | protease, serine, 23 | -0.0190192 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0186962 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.018639 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0181718 |
| VIM | vimentin | -0.0181674 |
| RPL37A | ribosomal protein L37a | -0.0179755 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0179624 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0178176 |
| S100A6 | S100 calcium binding protein A6 | -0.0176961 |
| TRIM56 | tripartite motif containing 56 | -0.0175995 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0175626 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0175284 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0175187 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0174781 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0174342 |
| RPL31 | ribosomal protein L31 | -0.0174141 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0174087 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0171573 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0170415 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.016928 |
