Retinoic acid_PANC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Retinoic acid perturbation in PANC-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Retinoic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.204058
TRIO trio Rho guanine nucleotide exchange factor 0.0879074
THSD4 thrombospondin, type I, domain containing 4 0.0873652
INTS6 integrator complex subunit 6 0.0775234
MACF1 microtubule-actin crosslinking factor 1 0.0765909
PTK2 protein tyrosine kinase 2 0.0668389
AKAP12 A kinase (PRKA) anchor protein 12 0.0642564
HMGA2 high mobility group AT-hook 2 0.0614421
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0608057
AHNAK AHNAK nucleoprotein 0.0605126
FNDC3B fibronectin type III domain containing 3B 0.0597464
SLC35F3 solute carrier family 35, member F3 0.0593762
DST dystonin 0.0516916
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0478799
ANKRD11 ankyrin repeat domain 11 0.0473006
CTBP2 C-terminal binding protein 2 0.0471065
TNS3 tensin 3 0.0459348
NAV2 neuron navigator 2 0.0455933
FMNL2 formin-like 2 0.0444117
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0430538
ZSWIM6 zinc finger, SWIM-type containing 6 0.0423407
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0421007
RNF220 ring finger protein 220 0.0418322
EHBP1 EH domain binding protein 1 0.0399905
RAD51B RAD51 paralog B 0.0393581
LPP LIM domain containing preferred translocation partner in lipoma 0.038648
SEPTIN9 septin 9 0.0379053
NHSL1 NHS-like 1 0.0377933
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0371919
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.036313
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0357836
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0351731
SDK1 sidekick cell adhesion molecule 1 0.0350101
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0336293
MYO1E myosin IE 0.033367
ZFAND3 zinc finger, AN1-type domain 3 0.0330103
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0329352
EGFR epidermal growth factor receptor 0.032931
VCL vinculin 0.0328622
MYO10 myosin X 0.0326431
AKAP13 A kinase (PRKA) anchor protein 13 0.0325955
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0325447
HSPG2 heparan sulfate proteoglycan 2 0.0309396
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0309361
EXT1 exostosin glycosyltransferase 1 0.0304101
DIAPH2 diaphanous-related formin 2 0.0301393
PDLIM5 PDZ and LIM domain 5 0.0294059
NUP98 nucleoporin 98kDa 0.029283
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0289052
CUX1 cut-like homeobox 1 0.0275782
TPM1 tropomyosin 1 (alpha) 0.0275181
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0270099
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0268739
ATXN1 ataxin 1 0.0266986
DOCK1 dedicator of cytokinesis 1 0.0265786
RIGI RNA sensor RIG-I 0.0264688
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0264413
MAML3 mastermind-like 3 (Drosophila) 0.0259706
TCF12 transcription factor 12 0.0259238
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0259039
CMIP c-Maf inducing protein 0.0256616
UBAP2 ubiquitin associated protein 2 0.0255748
FNIP1 folliculin interacting protein 1 0.0251208
ATG7 autophagy related 7 0.0250961
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0250156
IGF1R insulin-like growth factor 1 receptor 0.0248358
ZDHHC14 zinc finger, DHHC-type containing 14 0.0246198
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0246013
NPAS2 neuronal PAS domain protein 2 0.0238704
TIAM2 T-cell lymphoma invasion and metastasis 2 0.0234662
VEGFA vascular endothelial growth factor A 0.0232948
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0232345
ZNF407 zinc finger protein 407 0.0230012
ZNF638 zinc finger protein 638 0.0229658
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0226856
CDK13 cyclin-dependent kinase 13 0.0223391
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0219684
PRKCA protein kinase C, alpha 0.0218075
MSN moesin 0.0217863
MSRB3 methionine sulfoxide reductase B3 0.0217719
RABGAP1L RAB GTPase activating protein 1-like 0.0216084
EXOC4 exocyst complex component 4 0.0214214
HDAC4 histone deacetylase 4 0.0210833
ARHGAP32 Rho GTPase activating protein 32 0.0209972
RPTOR regulatory associated protein of MTOR, complex 1 0.0209451
FGGY FGGY carbohydrate kinase domain containing 0.0209301
PRELID2 PRELI domain containing 2 0.020601
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0204278
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.0202583
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0200593
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 0.0200306
HDAC9 histone deacetylase 9 0.0199603
SIK3 SIK family kinase 3 0.0198338
PRKCE protein kinase C, epsilon 0.0196099
FMN1 formin 1 0.0190719
CTSD cathepsin D 0.0189656
ERBIN erbb2 interacting protein 0.0189597
LARS1 leucyl-tRNA synthetase 1 0.0189028
PICALM phosphatidylinositol binding clathrin assembly protein 0.0188997
DENND1A DENN/MADD domain containing 1A 0.0186762

decreased expression

Symbol Name Standardized Value
RPS16 ribosomal protein S16 -0.217177
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.145182
VIM vimentin -0.135515
CD44 CD44 molecule (Indian blood group) -0.0992127
TXNRD1 thioredoxin reductase 1 -0.0922316
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0864709
ACTN4 actinin, alpha 4 -0.0842234
ANXA2 annexin A2 -0.0832727
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.082439
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0804541
FBL fibrillarin -0.0650437
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0643185
RTN4 reticulon 4 -0.0615914
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0612328
TMEM41B transmembrane protein 41B -0.0609695
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.0599259
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.05895
LOC112694756 uncharaterized LOC112694756 -0.0553519
YBX1 Y box binding protein 1 -0.0538591
EIF1 eukaryotic translation initiation factor 1 -0.0530568
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0525407
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0497145
MORF4L2 mortality factor 4 like 2 -0.0486242
RPLP0 ribosomal protein, large, P0 -0.0485741
RPLP1 ribosomal protein, large, P1 -0.0474716
FOSL1 FOS-like antigen 1 -0.0474383
ENO1 enolase 1, (alpha) -0.0464597
IPO7 importin 7 -0.0436325
MT2A metallothionein 2A -0.0424868
ACTG1 actin gamma 1 -0.0417577
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -0.0415701
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -0.0405034
WWTR1 WW domain containing transcription regulator 1 -0.0403717
TMEM123 transmembrane protein 123 -0.0399444
NAP1L1 nucleosome assembly protein 1-like 1 -0.039553
ZNF292 zinc finger protein 292 -0.0378413
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0366173
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0354627
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0354605
B2M beta-2-microglobulin -0.0345642
KPNB1 karyopherin (importin) beta 1 -0.0344846
ANLN anillin, actin binding protein -0.0344176
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0339723
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0338366
S100A10 S100 calcium binding protein A10 -0.0336451
PGK1 phosphoglycerate kinase 1 -0.0328056
BIRC2 baculoviral IAP repeat containing 2 -0.0327789
NCEH1 neutral cholesterol ester hydrolase 1 -0.0325162
S100A6 S100 calcium binding protein A6 -0.0322908
WDR45B WD repeat domain 45B -0.0319782
PDIA3 protein disulfide isomerase family A, member 3 -0.0318621
ARHGAP29 Rho GTPase activating protein 29 -0.0317692
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0314816
CENPF centromere protein F, 350/400kDa -0.0313017
MKI67 marker of proliferation Ki-67 -0.0308167
SFTPA2 surfactant protein A2 -0.0304287
CANX calnexin -0.0303712
EEF2 eukaryotic translation elongation factor 2 -0.0300141
NAMPT nicotinamide phosphoribosyltransferase -0.0290469
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0286252
SPAG9 sperm associated antigen 9 -0.0284689
RPL12 ribosomal protein L12 -0.0282608
FHL2 four and a half LIM domains 2 -0.0281552
RPL4 ribosomal protein L4 -0.0279801
RAD21 RAD21 homolog (S. pombe) -0.0278954
DSTN destrin (actin depolymerizing factor) -0.027583
KLF6 Kruppel-like factor 6 -0.0275355
KTN1 kinectin 1 (kinesin receptor) -0.0265901
MATR3 matrin 3 -0.0265327
CALU calumenin -0.0261502
ADGRG6 adhesion G protein-coupled receptor G6 -0.0258034
LDHA lactate dehydrogenase A -0.025655
GARS1 glycyl-tRNA synthetase 1 -0.0254347
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0252694
RPL11 ribosomal protein L11 -0.0247797
UBC ubiquitin C -0.0247179
SLC38A2 solute carrier family 38, member 2 -0.0244647
GOLGA4 golgin A4 -0.0244398
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.024398
RPL27A ribosomal protein L27a -0.0242891
RPL28 ribosomal protein L28 -0.0242241
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.024184
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0240344
MED29 mediator complex subunit 29 -0.0237789
FTH1 ferritin, heavy polypeptide 1 -0.02355
APP amyloid beta (A4) precursor protein -0.0231215
CALR calreticulin -0.0231065
RPS5 ribosomal protein S5 -0.0227958
SMC4 structural maintenance of chromosomes 4 -0.0226315
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0226033
RPS8 ribosomal protein S8 -0.022596
DGKD diacylglycerol kinase, delta 130kDa -0.022583
IMMT inner membrane protein, mitochondrial -0.0222062
SEC63 SEC63 homolog (S. cerevisiae) -0.0220057
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0219294
TPX2 TPX2, microtubule-associated -0.0217634
MYH9 myosin, heavy chain 9, non-muscle -0.0217443
VDAC1 voltage-dependent anion channel 1 -0.0216949
CAV1 caveolin 1, caveolae protein, 22kDa -0.0216351
RACK1 receptor for activated C kinase 1 -0.0216278