| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Retinoic acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Retinoic acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.138333 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.114705 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0957416 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0890559 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0876003 |
| HDAC9 | histone deacetylase 9 | 0.0848909 |
| EGR1 | early growth response 1 | 0.0840146 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0753986 |
| B2M | beta-2-microglobulin | 0.0751461 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0701759 |
| TMEM178B | transmembrane protein 178B | 0.0683241 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0670692 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0612273 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0600529 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0527703 |
| COL5A1 | collagen, type V, alpha 1 | 0.0522255 |
| CADM1 | cell adhesion molecule 1 | 0.0512235 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0506591 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0490497 |
| NAV1 | neuron navigator 1 | 0.0489449 |
| VEGFA | vascular endothelial growth factor A | 0.0482998 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0477234 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0459174 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0452829 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0452702 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.044959 |
| SP100 | SP100 nuclear antigen | 0.0430414 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0412136 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0407425 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0407118 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0405492 |
| FHIT | fragile histidine triad | 0.0403191 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0401377 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0399472 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0394344 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0389783 |
| SMAD3 | SMAD family member 3 | 0.0386547 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0386075 |
| TGM2 | transglutaminase 2 | 0.0377317 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0375195 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0373277 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0368722 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.03629 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0362897 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0357159 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.034991 |
| COL5A3 | collagen, type V, alpha 3 | 0.0346496 |
| JUN | jun proto-oncogene | 0.0344498 |
| DST | dystonin | 0.0344296 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0344234 |
| HLA-B | major histocompatibility complex, class I, B | 0.0343138 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0342425 |
| ADM | adrenomedullin | 0.0333814 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0333744 |
| LOXL2 | lysyl oxidase-like 2 | 0.0329739 |
| RND3 | Rho family GTPase 3 | 0.0327619 |
| MCL1 | myeloid cell leukemia 1 | 0.03268 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0318254 |
| SQSTM1 | sequestosome 1 | 0.0317805 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0315306 |
| CD109 | CD109 molecule | 0.0312809 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0312035 |
| FTL | ferritin, light polypeptide | 0.0311801 |
| TGFB1 | transforming growth factor, beta 1 | 0.0311741 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0306826 |
| BRD2 | bromodomain containing 2 | 0.0306091 |
| FRMD5 | FERM domain containing 5 | 0.0303785 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0302702 |
| ANXA2 | annexin A2 | 0.0300694 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0300478 |
| INTS6 | integrator complex subunit 6 | 0.0296854 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0295998 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0287686 |
| RYBP | RING1 and YY1 binding protein | 0.0284336 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.028396 |
| PKM | pyruvate kinase, muscle | 0.0283622 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0281891 |
| RAI14 | retinoic acid induced 14 | 0.0274162 |
| CDH13 | cadherin 13 | 0.0267906 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267427 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0265321 |
| FBXO32 | F-box protein 32 | 0.0264335 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0263508 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0263075 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0260696 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0260273 |
| ECE1 | endothelin converting enzyme 1 | 0.0259569 |
| PLAT | plasminogen activator, tissue | 0.0259308 |
| HLA-A | major histocompatibility complex, class I, A | 0.025896 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0256625 |
| MYOF | myoferlin | 0.0255739 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0253776 |
| HLA-E | major histocompatibility complex, class I, E | 0.0247485 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0246866 |
| SFTPA2 | surfactant protein A2 | 0.0246208 |
| CCNL1 | cyclin L1 | 0.0245386 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0245275 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0244533 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0244439 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0243556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.196281 |
| FN1 | fibronectin 1 | -0.146552 |
| NDRG1 | N-myc downstream regulated 1 | -0.124071 |
| PGK1 | phosphoglycerate kinase 1 | -0.113112 |
| CD44 | CD44 molecule (Indian blood group) | -0.108587 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.10135 |
| MT2A | metallothionein 2A | -0.0904522 |
| CENPF | centromere protein F, 350/400kDa | -0.0868034 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0863258 |
| STC1 | stanniocalcin 1 | -0.0774188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0762699 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0750962 |
| TMSB10 | thymosin beta 10 | -0.0651314 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0642481 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.06155 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0605749 |
| ZNF292 | zinc finger protein 292 | -0.0560858 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0547721 |
| CENPE | centromere protein E, 312kDa | -0.0546454 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0542122 |
| CDCP1 | CUB domain containing protein 1 | -0.0539441 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0528174 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0525675 |
| DIAPH3 | diaphanous-related formin 3 | -0.05189 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0516695 |
| AFAP1 | actin filament associated protein 1 | -0.0515867 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0513599 |
| MKI67 | marker of proliferation Ki-67 | -0.0492186 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0491215 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0469951 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0468188 |
| RRBP1 | ribosome binding protein 1 | -0.0431373 |
| GOLGA4 | golgin A4 | -0.0428054 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0424693 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0423219 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.042204 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0412275 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0410345 |
| ANLN | anillin, actin binding protein | -0.0406218 |
| RTN4 | reticulon 4 | -0.0401531 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0396297 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0394314 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0394027 |
| SGO2 | shugoshin 2 | -0.0388319 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0388312 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0381441 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0381388 |
| HMGB2 | high mobility group box 2 | -0.0378288 |
| ANKRD12 | ankyrin repeat domain 12 | -0.036705 |
| TPX2 | TPX2, microtubule-associated | -0.036364 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0360332 |
| SSH1 | slingshot protein phosphatase 1 | -0.035497 |
| KIF4A | kinesin family member 4A | -0.0352991 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0351439 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0348628 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0345643 |
| RPS21 | ribosomal protein S21 | -0.0332934 |
| THBS1 | thrombospondin 1 | -0.033102 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0327511 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.032595 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0325466 |
| OSMR | oncostatin M receptor | -0.0325025 |
| FRMD4A | FERM domain containing 4A | -0.0323762 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0320603 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0309734 |
| SBF2 | SET binding factor 2 | -0.0302945 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0299966 |
| NF1 | neurofibromin 1 | -0.0296314 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0295434 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0295373 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0294525 |
| KLF6 | Kruppel-like factor 6 | -0.0293671 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0287129 |
| PDE10A | phosphodiesterase 10A | -0.0287104 |
| FAM20C | family with sequence similarity 20, member C | -0.0278498 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0277099 |
| AHNAK | AHNAK nucleoprotein | -0.0276563 |
| TUBB | tubulin, beta class I | -0.0276106 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0275369 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0275059 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0274323 |
| TPM1 | tropomyosin 1 (alpha) | -0.0273682 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0272801 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0272185 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0267658 |
| OGA | O-GlcNAcase | -0.0266824 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0264861 |
| HM13 | histocompatibility (minor) 13 | -0.0263113 |
| IER3 | immediate early response 3 | -0.0259219 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0259169 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258314 |
| CDC27 | cell division cycle 27 | -0.0255063 |
| NUMB | numb homolog (Drosophila) | -0.0253344 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0252051 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0250184 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0248527 |
| TTK | TTK protein kinase | -0.0247628 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0247201 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0243813 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0243231 |
