Retinopathy Of Prematurity Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1443381
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Genes

190 genes associated with the disease Retinopathy Of Prematurity in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTB actin, beta
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
APLN apelin
AQP1 aquaporin 1 (Colton blood group)
ATF4 activating transcription factor 4
ATG5 autophagy related 5
ATRAID all-trans retinoic acid-induced differentiation factor
BCAP31 B-cell receptor-associated protein 31
BDNF brain-derived neurotrophic factor
C3 complement component 3
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL5 chemokine (C-C motif) ligand 5
CCN1 cellular communication network factor 1
CCR7 chemokine (C-C motif) receptor 7
CDCA5 cell division cycle associated 5
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CFL1 cofilin 1 (non-muscle)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNTF ciliary neurotrophic factor
COL18A1 collagen, type XVIII, alpha 1
CRP C-reactive protein, pentraxin-related
CXCL8 chemokine (C-X-C motif) ligand 8
DLL4 delta-like 4 (Drosophila)
DNALI1 dynein, axonemal, light intermediate chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDN1 endothelin 1
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
EPHX2 epoxide hydrolase 2, cytoplasmic
EPO erythropoietin
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAM188B family with sequence similarity 188, member B
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FLT1 fms-related tyrosine kinase 1
FZD1 frizzled class receptor 1
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
GAP43 growth associated protein 43
GCA grancalcin, EF-hand calcium binding protein
GCHFR GTP cyclohydrolase I feedback regulator
GCLC glutamate-cysteine ligase, catalytic subunit
GFAP glial fibrillary acidic protein
GMCL1 germ cell-less, spermatogenesis associated 1
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1
GOSR1 golgi SNAP receptor complex member 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTT1 glutathione S-transferase theta 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLF hepatic leukemia factor
HMOX1 heme oxygenase 1
HPSE heparanase
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IHH indian hedgehog
IL12A interleukin 12A
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL27 interleukin 27
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
JAM3 junctional adhesion molecule 3
KDR kinase insert domain receptor
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LOC105375355 uroplakin-3b
LPA lipoprotein, Lp(a)
LPAR1 lysophosphatidic acid receptor 1
LRP5 low density lipoprotein receptor-related protein 5
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAPK1 mitogen-activated protein kinase 1
MARCHF1 membrane associated ring-CH-type finger 1
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCPH1 microcephalin 1
MET MET proto-oncogene, receptor tyrosine kinase
MGA MGA, MAX dimerization protein
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NDP Norrie disease (pseudoglioma)
NGF nerve growth factor (beta polypeptide)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NRP1 neuropilin 1
NRP2 neuropilin 2
NTF3 neurotrophin 3
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
PAX2 paired box 2
PF4 platelet factor 4
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLXNA2 plexin A2
PNPLA2 patatin-like phospholipase domain containing 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRL prolactin
PROS1 protein S (alpha)
PRSS23 protease, serine, 23
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTN pleiotrophin
QKI QKI, KH domain containing, RNA binding
REN renin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL41 ribosomal protein L41
RPP14 ribonuclease P/MRP 14kDa subunit
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SCG3 secretogranin III
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN2 sestrin 2
SETD2 SET domain containing 2
SF3B6 splicing factor 3b, subunit 6, 14kDa
SIAE sialic acid acetylesterase
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STC1 stanniocalcin 1
STK26 serine/threonine protein kinase 26
SUB1 SUB1 homolog (S. cerevisiae)
SUCNR1 succinate receptor 1
TBX5 T-box 5
TEAD4 TEA domain family member 4
TEK TEK tyrosine kinase, endothelial
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TM7SF2 transmembrane 7 superfamily member 2
TMED5 transmembrane emp24 protein transport domain containing 5
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53BP1 tumor protein p53 binding protein 1
TPPP2 tubulin polymerization-promoting protein family member 2
TREM1 triggering receptor expressed on myeloid cells 1
TSPAN12 tetraspanin 12
TUBA1A tubulin, alpha 1a
UBE2I ubiquitin-conjugating enzyme E2I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
ZNF197 zinc finger protein 197
ZNF280C zinc finger protein 280C