Rett Syndrome_frontal cortex_GSE6955 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6955
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Genes

600 genes differentially expressed during Rett Syndrome_frontal cortex_GSE6955 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 4.33192
ZNF43 zinc finger protein 43 4.31713
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 4.17419
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 4.06397
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 3.91459
TST thiosulfate sulfurtransferase (rhodanese) 3.85357
TPD52 tumor protein D52 3.77422
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 3.75767
ARL1 ADP-ribosylation factor-like 1 3.72786
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 3.62007
VRK1 vaccinia related kinase 1 3.56969
PLK1 polo-like kinase 1 3.56172
SLC4A2 solute carrier family 4 (anion exchanger), member 2 3.55626
ALX3 ALX homeobox 3 3.55077
ERICH1 glutamate-rich 1 3.45039
ADGRA3 adhesion G protein-coupled receptor A3 3.40907
MYO10 myosin X 3.39927
DKFZP547J0410 DKFZP547J0410 protein 3.38584
METTL7A methyltransferase like 7A 3.33305
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 3.23941
CLDN10 claudin 10 3.22548
ALOX15 arachidonate 15-lipoxygenase 3.17404
HSPH1 heat shock 105kDa/110kDa protein 1 3.16702
TRIL TLR4 interactor with leucine-rich repeats 3.13249
NCAM2 neural cell adhesion molecule 2 3.11098
DOLK dolichol kinase 3.07187
GPC5 glypican 5 3.01666
PTN pleiotrophin 3.01371
FAM149A family with sequence similarity 149, member A 2.96549
LPAR4 lysophosphatidic acid receptor 4 2.93341
SCRG1 stimulator of chondrogenesis 1 2.8875
INSR insulin receptor 2.86112
LTK leukocyte receptor tyrosine kinase 2.85697
HEPH hephaestin 2.85382
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.82596
ZFR2 zinc finger RNA binding protein 2 2.8132
RHOH ras homolog family member H 2.78501
FAM107A family with sequence similarity 107, member A 2.75908
ZNF254 zinc finger protein 254 2.71455
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 2.70407
PGAM2 phosphoglycerate mutase 2 (muscle) 2.69398
LRP4 low density lipoprotein receptor-related protein 4 2.66468
FAT1 FAT atypical cadherin 1 2.63718
IAPP islet amyloid polypeptide 2.63196
SQLE squalene epoxidase 2.61402
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.61101
STAG1 stromal antigen 1 2.60677
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.60061
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.59366
GPM6B glycoprotein M6B 2.58683
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 2.55563
MT1G metallothionein 1G 2.53332
FAM89B family with sequence similarity 89, member B 2.51921
MAU2 MAU2 sister chromatid cohesion factor 2.51748
SASH1 SAM and SH3 domain containing 1 2.48879
SGMS1 sphingomyelin synthase 1 2.46958
NXPH2 neurexophilin 2 2.45507
SOS2 son of sevenless homolog 2 (Drosophila) 2.44398
PAEP progestagen-associated endometrial protein 2.41646
ADSL adenylosuccinate lyase 2.41364
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 2.3791
RPP38 ribonuclease P/MRP 38kDa subunit 2.36913
SNTA1 syntrophin, alpha 1 2.36165
SFRP1 secreted frizzled-related protein 1 2.35086
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.33389
LPO lactoperoxidase 2.32104
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.29792
RAD52 RAD52 homolog (S. cerevisiae) 2.27703
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.25832
CALU calumenin 2.25803
MKI67 marker of proliferation Ki-67 2.2534
MEIS2 Meis homeobox 2 2.24825
BAMBI BMP and activin membrane-bound inhibitor 2.23494
CD19 CD19 molecule 2.22016
SRI sorcin 2.21602
FAM49A family with sequence similarity 49, member A 2.21045
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 2.20516
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.19481
RBM15B RNA binding motif protein 15B 2.1519
WIF1 WNT inhibitory factor 1 2.11878
MRPS14 mitochondrial ribosomal protein S14 2.0995
CYB561 cytochrome b561 2.09378
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.09078
PAX3 paired box 3 2.07405
PAX6 paired box 6 2.06907
NCOA2 nuclear receptor coactivator 2 2.06899
AK4 adenylate kinase 4 2.06075
GLRA3 glycine receptor, alpha 3 2.0607
SOX9 SRY (sex determining region Y)-box 9 2.0584
TYMS thymidylate synthetase 2.05739
LYPD3 LY6/PLAUR domain containing 3 2.05123
COL4A4 collagen, type IV, alpha 4 2.04616
HIPK1 homeodomain interacting protein kinase 1 2.04187
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 2.03697
MSMO1 methylsterol monooxygenase 1 2.03667
SUCO SUN domain containing ossification factor 2.03093
AP3B1 adaptor-related protein complex 3, beta 1 subunit 2.02052
MED1 mediator complex subunit 1 2.01726
AHCYL2 adenosylhomocysteinase-like 2 2.01564
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.01467
NFX1 nuclear transcription factor, X-box binding 1 2.00677
TEF thyrotrophic embryonic factor 1.99668
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 1.99537
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.97174
WSCD1 WSC domain containing 1 1.962
PDLIM7 PDZ and LIM domain 7 (enigma) 1.95236
SCCPDH saccharopine dehydrogenase (putative) 1.95102
JAKMIP1 janus kinase and microtubule interacting protein 1 1.95062
CADM4 cell adhesion molecule 4 1.94552
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.93718
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.93519
LMO3 LIM domain only 3 (rhombotin-like 2) 1.92452
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 1.91985
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.91944
RSC1A1 regulatory solute carrier protein, family 1, member 1 1.91584
BRSK2 BR serine/threonine kinase 2 1.9127
NAV3 neuron navigator 3 1.89741
SFTPD surfactant protein D 1.8946
DIEXF digestive organ expansion factor homolog (zebrafish) 1.88865
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.88462
KDM5B lysine (K)-specific demethylase 5B 1.87655
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.86599
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 1.85674
FADS1 fatty acid desaturase 1 1.84848
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.84807
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.83819
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.83505
FADS2 fatty acid desaturase 2 1.83102
ANGEL1 angel homolog 1 (Drosophila) 1.82858
ZNF80 zinc finger protein 80 1.82585
SBNO2 strawberry notch homolog 2 (Drosophila) 1.8256
HRSP12 heat-responsive protein 12 1.82502
ZFP37 ZFP37 zinc finger protein 1.82158
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.82133
ACACA acetyl-CoA carboxylase alpha 1.81381
CIRBP cold inducible RNA binding protein 1.80965
EZR ezrin 1.79787
ADD3 adducin 3 (gamma) 1.79631
DIO2 deiodinase, iodothyronine, type II 1.79552
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1.79084
ZNF415 zinc finger protein 415 1.78842
ECI1 enoyl-CoA delta isomerase 1 1.78815
INHBC inhibin, beta C 1.78758
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.78382
C1ORF21 chromosome 1 open reading frame 21 1.7718
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.76964
AXL AXL receptor tyrosine kinase 1.7622
FGFR3 fibroblast growth factor receptor 3 1.75636
C1ORF61 chromosome 1 open reading frame 61 1.75496
ZNF629 zinc finger protein 629 1.75091
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.74927
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.74204
DZIP1 DAZ interacting zinc finger protein 1 1.74006
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding) 1.7379
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.73039
PRPF4 pre-mRNA processing factor 4 1.72907
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.7281
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.72692
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.72337
RGS20 regulator of G-protein signaling 20 1.72328
GJA1 gap junction protein, alpha 1, 43kDa 1.69221
MDFIC MyoD family inhibitor domain containing 1.69159
ZNRD1-AS1 ZNRD1 antisense RNA 1 1.68301
SELENBP1 selenium binding protein 1 1.67521
CTNS cystinosin, lysosomal cystine transporter 1.67499
GLG1 golgi glycoprotein 1 1.65854
NTSR2 neurotensin receptor 2 1.65812
ACOT11 acyl-CoA thioesterase 11 1.65309
GAS1 growth arrest-specific 1 1.64648
GLI2 GLI family zinc finger 2 1.63756
WASF3 WAS protein family, member 3 1.63665
STAB1 stabilin 1 1.63157
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 1.63113
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.62973
PSIP1 PC4 and SFRS1 interacting protein 1 1.62661
ZFX zinc finger protein, X-linked 1.62207
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 1.61073
THBS1 thrombospondin 1 1.60671
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 1.59073
CKS1B CDC28 protein kinase regulatory subunit 1B 1.58816
MAMLD1 mastermind-like domain containing 1 1.58727
CHD3 chromodomain helicase DNA binding protein 3 1.57627
ARHGAP5 Rho GTPase activating protein 5 1.57552
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.56334
PEG10 paternally expressed 10 1.56272
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.55406
BAZ2A bromodomain adjacent to zinc finger domain, 2A 1.55306
ZNF33B zinc finger protein 33B 1.55249
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.5522
GLUD1 glutamate dehydrogenase 1 1.55102
PDLIM3 PDZ and LIM domain 3 1.54862
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.54791
MYBPC3 myosin binding protein C, cardiac 1.54445
CYC1 cytochrome c-1 1.54314
FUBP3 far upstream element (FUSE) binding protein 3 1.54119
DCLRE1A DNA cross-link repair 1A 1.53728
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 1.53667
C5 complement component 5 1.53544
PUM1 pumilio RNA-binding family member 1 1.53409
DUSP7 dual specificity phosphatase 7 1.53366
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.53233
MYO1C myosin IC 1.53015
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head) 1.52899
PACRG PARK2 co-regulated 1.52494
CBS cystathionine-beta-synthase 1.51196
SEPT11 septin 11 1.50446
ITGA7 integrin, alpha 7 1.50309
DRD4 dopamine receptor D4 1.50048
FOXA2 forkhead box A2 1.49468
UTRN utrophin 1.49222
HTRA1 HtrA serine peptidase 1 1.49112
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.48665
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.48665
TOB1 transducer of ERBB2, 1 1.48438
FYN FYN proto-oncogene, Src family tyrosine kinase 1.47966
SGSM2 small G protein signaling modulator 2 1.47617
HELZ helicase with zinc finger 1.47584
GOLGA1 golgin A1 1.4719
HPD 4-hydroxyphenylpyruvate dioxygenase 1.47163
BTF3 basic transcription factor 3 1.47007
GLUD2 glutamate dehydrogenase 2 1.46669
ELAVL1 ELAV like RNA binding protein 1 1.46446
RUNX2 runt-related transcription factor 2 1.46011
ITGB5 integrin, beta 5 1.45512
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 1.45424
AHNAK AHNAK nucleoprotein 1.45348
GAS2L1 growth arrest-specific 2 like 1 1.45069
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 1.45061
NNT nicotinamide nucleotide transhydrogenase 1.44892
POFUT2 protein O-fucosyltransferase 2 1.44694
PPP1R3C protein phosphatase 1, regulatory subunit 3C 1.4464
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.44382
ZNF428 zinc finger protein 428 1.43259
CPQ carboxypeptidase Q 1.42709
ASIC3 acid sensing (proton gated) ion channel 3 1.42616
PGAP1 post-GPI attachment to proteins 1 1.42385
ZEB1 zinc finger E-box binding homeobox 1 1.41916
ZNF510 zinc finger protein 510 1.41696
ERCC2 excision repair cross-complementation group 2 1.41418
MUC2 mucin 2, oligomeric mucus/gel-forming 1.4102
QKI QKI, KH domain containing, RNA binding 1.40862
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 1.40337
ZNF710 zinc finger protein 710 1.40276
EFNA2 ephrin-A2 1.40138
CAMLG calcium modulating ligand 1.39628
DDN dendrin 1.39323
LLGL2 lethal giant larvae homolog 2 (Drosophila) 1.39163
CUL7 cullin 7 1.39096
ZZZ3 zinc finger, ZZ-type containing 3 1.37822
FOXG1 forkhead box G1 1.37233
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.36741
DCX doublecortin 1.36408
ACADSB acyl-CoA dehydrogenase, short/branched chain 1.36361
PPP6R2 protein phosphatase 6, regulatory subunit 2 1.35924
BCR breakpoint cluster region 1.35267
KIAA0485 uncharacterized LOC57235 1.35169
POFUT1 protein O-fucosyltransferase 1 1.34917
MAOA monoamine oxidase A 1.34865
CXCL5 chemokine (C-X-C motif) ligand 5 1.34461
RND2 Rho family GTPase 2 1.3427
ANKRD17 ankyrin repeat domain 17 1.34065
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.33606
DRD1 dopamine receptor D1 1.33591
CCDC6 coiled-coil domain containing 6 1.33263
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 1.33011
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.32623
COL6A2 collagen, type VI, alpha 2 1.31911
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 1.31403
PALLD palladin, cytoskeletal associated protein 1.30988
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.30919
CIC capicua transcriptional repressor 1.30404
WDFY3 WD repeat and FYVE domain containing 3 1.30391
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.29808
IGSF9B immunoglobulin superfamily, member 9B 1.29734
CNOT4 CCR4-NOT transcription complex, subunit 4 1.29616
PDS5B PDS5 cohesin associated factor B 1.28962
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.28852
NEK7 NIMA-related kinase 7 1.28004
RBBP7 retinoblastoma binding protein 7 1.27907
SLC25A40 solute carrier family 25, member 40 1.27891
DLK1 delta-like 1 homolog (Drosophila) 1.27737
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.27671
NEK4 NIMA-related kinase 4 1.27453
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.27342
PPP1R8 protein phosphatase 1, regulatory subunit 8 1.27308
ANXA4 annexin A4 1.27007
QRICH1 glutamine-rich 1 1.26555
IQSEC1 IQ motif and Sec7 domain 1 1.26549
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 1.26307
FABP6 fatty acid binding protein 6, ileal 1.26226
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.26091
CHMP2B charged multivesicular body protein 2B 1.25254
TES testin LIM domain protein 1.25148
CAT catalase 1.25047
MEF2D myocyte enhancer factor 2D 1.24998
UROD uroporphyrinogen decarboxylase 1.24598
DEAF1 DEAF1 transcription factor 1.24227
RABL3 RAB, member of RAS oncogene family-like 3 1.23754
CD84 CD84 molecule 1.23748
ABLIM3 actin binding LIM protein family, member 3 1.23738

decreased expression

Symbol Name Standardized Value
CARTPT CART prepropeptide -5.08977
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -3.82401
ZIC3 Zic family member 3 -3.77043
NCAPH non-SMC condensin I complex, subunit H -3.19946
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -2.19187
IL10RA interleukin 10 receptor, alpha -2.04284
FMO3 flavin containing monooxygenase 3 -2.01585
AAK1 AP2 associated kinase 1 -1.78975
SLPI secretory leukocyte peptidase inhibitor -1.61641
IRF2BP1 interferon regulatory factor 2 binding protein 1 -1.6145
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.59626
PITX1 paired-like homeodomain 1 -1.57206
DEPDC5 DEP domain containing 5 -1.5569
ABHD2 abhydrolase domain containing 2 -1.47296
RBM4B RNA binding motif protein 4B -1.44926
GLIPR1 GLI pathogenesis-related 1 -1.42641
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -1.36387
AMHR2 anti-Mullerian hormone receptor, type II -1.33104
AMIGO2 adhesion molecule with Ig-like domain 2 -1.3223
ATP11A ATPase, class VI, type 11A -1.31435
OCM2 oncomodulin 2 -1.28714
BRCA1 breast cancer 1, early onset -1.27169
AGFG1 ArfGAP with FG repeats 1 -1.25795
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 -1.22485
DHFR dihydrofolate reductase -1.21359
GRP gastrin-releasing peptide -1.2089
ALPP alkaline phosphatase, placental -1.20091
CHAF1A chromatin assembly factor 1, subunit A (p150) -1.1501
GNS glucosamine (N-acetyl)-6-sulfatase -1.1368
CELA2B chymotrypsin-like elastase family, member 2B -1.09028
COL7A1 collagen, type VII, alpha 1 -1.08245
PHLDA2 pleckstrin homology-like domain, family A, member 2 -1.05326
HAB1 B1 for mucin -1.0419
ACPP acid phosphatase, prostate -1.03427
KLK3 kallikrein-related peptidase 3 -1.03345
PAPPA2 pappalysin 2 -1.0315
PGM5 phosphoglucomutase 5 -1.03013
ADRA1A adrenoceptor alpha 1A -1.02365
ESYT1 extended synaptotagmin-like protein 1 -1.02202
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -1.00606
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -1.00289
TFAM transcription factor A, mitochondrial -0.960041
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.957873
BPI bactericidal/permeability-increasing protein -0.942958
MYCBP MYC binding protein -0.936596
CFD complement factor D (adipsin) -0.928325
FLT3LG fms-related tyrosine kinase 3 ligand -0.921953
IVNS1ABP influenza virus NS1A binding protein -0.905193
PIAS1 protein inhibitor of activated STAT, 1 -0.901537
ZNF195 zinc finger protein 195 -0.900244
BASP1 brain abundant, membrane attached signal protein 1 -0.888664
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.886473
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.879692
MTDH metadherin -0.877934
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.874755
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -0.859723
GPR65 G protein-coupled receptor 65 -0.859181
SAG S-antigen; retina and pineal gland (arrestin) -0.8552
NUDCD3 NudC domain containing 3 -0.848448
DOCK2 dedicator of cytokinesis 2 -0.848067
DNASE1L3 deoxyribonuclease I-like 3 -0.844519
POU1F1 POU class 1 homeobox 1 -0.843089
TCTN3 tectonic family member 3 -0.84196
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) -0.838039
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -0.816584
STATH statherin -0.809127
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.807001
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -0.806314
ATXN7L1 ataxin 7-like 1 -0.805547
USP6 ubiquitin specific peptidase 6 -0.805161
JRKL JRK-like -0.803943
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -0.801138
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.80033
OR7E12P olfactory receptor, family 7, subfamily E, member 12 pseudogene -0.799817
SOS1 son of sevenless homolog 1 (Drosophila) -0.799114
CDK2 cyclin-dependent kinase 2 -0.796663
KLK7 kallikrein-related peptidase 7 -0.793692
CGREF1 cell growth regulator with EF-hand domain 1 -0.788684
NCAPD2 non-SMC condensin I complex, subunit D2 -0.785634
LIPE lipase, hormone-sensitive -0.778393
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.776341
USP20 ubiquitin specific peptidase 20 -0.7685
CTSZ cathepsin Z -0.768007
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -0.767807
SNED1 sushi, nidogen and EGF-like domains 1 -0.765432
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -0.764684
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 -0.764364
SP1 Sp1 transcription factor -0.762121
OR2H1 olfactory receptor, family 2, subfamily H, member 1 -0.75798
GPR161 G protein-coupled receptor 161 -0.756703
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -0.755501
STAT1 signal transducer and activator of transcription 1, 91kDa -0.752091
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -0.748456
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -0.74663
CENPF centromere protein F, 350/400kDa -0.738374
NOX1 NADPH oxidase 1 -0.735632
SPAG1 sperm associated antigen 1 -0.732585
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -0.732091
ADAM12 ADAM metallopeptidase domain 12 -0.731236
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -0.731026
CHD8 chromodomain helicase DNA binding protein 8 -0.729874
YAP1 Yes-associated protein 1 -0.728005
TPP2 tripeptidyl peptidase II -0.727862
TBX10 T-box 10 -0.725582
ZNF250 zinc finger protein 250 -0.725453
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.723181
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -0.703081
NPFF neuropeptide FF-amide peptide precursor -0.69391
AGGF1 angiogenic factor with G patch and FHA domains 1 -0.686491
CCL5 chemokine (C-C motif) ligand 5 -0.684549
NCBP1 nuclear cap binding protein subunit 1, 80kDa -0.679195
SRRD SRR1 domain containing -0.676242
MSX2 msh homeobox 2 -0.67453
SLC38A6 solute carrier family 38, member 6 -0.671349
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -0.671063
LOC100129973 uncharacterized LOC100129973 -0.666819
NKX3-2 NK3 homeobox 2 -0.666749
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.666622
ACTB actin, beta -0.665985
TSPAN4 tetraspanin 4 -0.661065
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.660619
TBL2 transducin (beta)-like 2 -0.658047
PHTF1 putative homeodomain transcription factor 1 -0.658005
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -0.65381
LOC100506699 uncharacterized LOC100506699 -0.651343
CA5A carbonic anhydrase VA, mitochondrial -0.648545
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.64747
KLHL35 kelch-like family member 35 -0.647411
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.646585
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.641161
NFIA nuclear factor I/A -0.639469
SHBG sex hormone-binding globulin -0.638752
MFSD5 major facilitator superfamily domain containing 5 -0.63069
RBM42 RNA binding motif protein 42 -0.629295
SNCG synuclein, gamma (breast cancer-specific protein 1) -0.628612
STXBP5L syntaxin binding protein 5-like -0.62857
ANKRD34C ankyrin repeat domain 34C -0.626521
DSG1 desmoglein 1 -0.625664
TRAPPC10 trafficking protein particle complex 10 -0.625326
TOPBP1 topoisomerase (DNA) II binding protein 1 -0.622848
E2F1 E2F transcription factor 1 -0.61967
KIAA0196 KIAA0196 -0.619081
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.618043
LZTR1 leucine-zipper-like transcription regulator 1 -0.617454
NECAB3 N-terminal EF-hand calcium binding protein 3 -0.615592
MFSD10 major facilitator superfamily domain containing 10 -0.615301
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.613984
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 -0.613509
EGR1 early growth response 1 -0.613376
IFI6 interferon, alpha-inducible protein 6 -0.611905
RPP14 ribonuclease P/MRP 14kDa subunit -0.610117
TGM3 transglutaminase 3 -0.608593
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.604509
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -0.603687
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.603361
AFF3 AF4/FMR2 family, member 3 -0.602387
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -0.602274
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.599927
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.5994
NPHP1 nephronophthisis 1 (juvenile) -0.599058
S100P S100 calcium binding protein P -0.597042
ZFC3H1 zinc finger, C3H1-type containing -0.596991
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -0.596376
GSTA2 glutathione S-transferase alpha 2 -0.595905
NUMB numb homolog (Drosophila) -0.595596
JUND jun D proto-oncogene -0.593108
EVI2A ecotropic viral integration site 2A -0.592975
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.592055
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -0.588707
SRP54 signal recognition particle 54kDa -0.584707
HOXA4 homeobox A4 -0.584375
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.583107
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.582822
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.58215
S100A2 S100 calcium binding protein A2 -0.581502
HHLA1 HERV-H LTR-associating 1 -0.580167
AQP7 aquaporin 7 -0.579546
MX2 MX dynamin-like GTPase 2 -0.57927
PIGA phosphatidylinositol glycan anchor biosynthesis, class A -0.576758
PNPLA2 patatin-like phospholipase domain containing 2 -0.576358
CCNT2 cyclin T2 -0.575055
NUP93 nucleoporin 93kDa -0.57044
RBM25 RNA binding motif protein 25 -0.569823
ING1 inhibitor of growth family, member 1 -0.569315
TCEAL4 transcription elongation factor A (SII)-like 4 -0.566439
ASCL1 achaete-scute family bHLH transcription factor 1 -0.566318
ACIN1 apoptotic chromatin condensation inducer 1 -0.565812
RNASE3 ribonuclease, RNase A family, 3 -0.562134
PENK proenkephalin -0.560871
NRGN neurogranin (protein kinase C substrate, RC3) -0.557576
SOCS3 suppressor of cytokine signaling 3 -0.556698
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.555989
IGFBP3 insulin-like growth factor binding protein 3 -0.555805
RPIA ribose 5-phosphate isomerase A -0.555285
HIST1H2BD histone cluster 1, H2bd -0.554096
REL v-rel avian reticuloendotheliosis viral oncogene homolog -0.552822
STC1 stanniocalcin 1 -0.55185
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -0.548986
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.548477
OPRK1 opioid receptor, kappa 1 -0.547241
TDO2 tryptophan 2,3-dioxygenase -0.545368
KRT31 keratin 31, type I -0.542886
PURA purine-rich element binding protein A -0.542291
LRP5 low density lipoprotein receptor-related protein 5 -0.54174
ARID1A AT rich interactive domain 1A (SWI-like) -0.537723
CHD1 chromodomain helicase DNA binding protein 1 -0.537597
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -0.53608
C9ORF3 chromosome 9 open reading frame 3 -0.535534
MINK1 misshapen-like kinase 1 -0.535102
ALMS1 Alstrom syndrome protein 1 -0.534446
TDG thymine-DNA glycosylase -0.534255
GDI1 GDP dissociation inhibitor 1 -0.533249
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.531574
LRP10 low density lipoprotein receptor-related protein 10 -0.528411
RTN1 reticulon 1 -0.527902
ING2 inhibitor of growth family, member 2 -0.527581
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -0.527133
BIRC2 baculoviral IAP repeat containing 2 -0.523602
TPMT thiopurine S-methyltransferase -0.520089
TRAM2 translocation associated membrane protein 2 -0.519587
SMCP sperm mitochondria-associated cysteine-rich protein -0.51549
ADAM23 ADAM metallopeptidase domain 23 -0.515238
TSPAN1 tetraspanin 1 -0.514736
XPOT exportin, tRNA -0.514706
SELE selectin E -0.514203
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.513532
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -0.512492
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -0.511928
BAAT bile acid CoA:amino acid N-acyltransferase -0.5115
GMPS guanine monphosphate synthase -0.511307
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.511304
HPX hemopexin -0.510739
CDK1 cyclin-dependent kinase 1 -0.510143
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.510014
ALPK3 alpha-kinase 3 -0.509351
STC2 stanniocalcin 2 -0.508852
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -0.508237
PICK1 protein interacting with PRKCA 1 -0.507166
BMP1 bone morphogenetic protein 1 -0.506239
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -0.505759
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.505562
ADGRE1 adhesion G protein-coupled receptor E1 -0.505211
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -0.504891
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -0.504368
HIP1 huntingtin interacting protein 1 -0.50377
ETV6 ets variant 6 -0.503041
HIST1H2AC histone cluster 1, H2ac -0.502793
TMX1 thioredoxin-related transmembrane protein 1 -0.502002
NPTX2 neuronal pentraxin II -0.501506
YTHDC1 YTH domain containing 1 -0.500423
GYG2 glycogenin 2 -0.499815
GUCA1A guanylate cyclase activator 1A (retina) -0.499701
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.498942
JRK Jrk homolog (mouse) -0.498763
CSPG4 chondroitin sulfate proteoglycan 4 -0.498755
PHTF2 putative homeodomain transcription factor 2 -0.493716
SOCS7 suppressor of cytokine signaling 7 -0.492717
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.492451
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -0.4918
EGR2 early growth response 2 -0.491174
RBMS2 RNA binding motif, single stranded interacting protein 2 -0.490954
S100A4 S100 calcium binding protein A4 -0.490368
ADAM19 ADAM metallopeptidase domain 19 -0.49032
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -0.489654
TSPYL1 TSPY-like 1 -0.489644
TARBP2 TAR (HIV-1) RNA binding protein 2 -0.488997
ARAF A-Raf proto-oncogene, serine/threonine kinase -0.487251
TMEM8B transmembrane protein 8B -0.4864
DSP desmoplakin -0.486118
SYP synaptophysin -0.486066
PAPOLA poly(A) polymerase alpha -0.485075
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -0.484391
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) -0.483508
SIK2 salt-inducible kinase 2 -0.483217
DPY19L1 dpy-19-like 1 (C. elegans) -0.481803
ADAM5 ADAM metallopeptidase domain 5 (pseudogene) -0.481694
RDX radixin -0.481058
ARHGAP4 Rho GTPase activating protein 4 -0.479075
CUL4A cullin 4A -0.477006
SDCBP syndecan binding protein (syntenin) -0.476132
RUFY3 RUN and FYVE domain containing 3 -0.476103
FOSL2 FOS-like antigen 2 -0.475967
TBX5 T-box 5 -0.47575
GGT5 gamma-glutamyltransferase 5 -0.475696
EMP3 epithelial membrane protein 3 -0.474695
TRIP6 thyroid hormone receptor interactor 6 -0.473676
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.472536
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.471621
RGS9 regulator of G-protein signaling 9 -0.471568
TMSB4X thymosin beta 4, X-linked -0.4707
KCTD7 potassium channel tetramerization domain containing 7 -0.470459
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -0.470458
MME membrane metallo-endopeptidase -0.46958
GH2 growth hormone 2 -0.469543
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.469203
KIAA0894 KIAA0894 protein -0.468762
IVL involucrin -0.468519
TCERG1 transcription elongation regulator 1 -0.466917
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -0.466855
YIPF1 Yip1 domain family, member 1 -0.465951