Rheumatism Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0035435
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Genes

187 genes associated with the disease Rheumatism in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACAD8 acyl-CoA dehydrogenase family, member 8
ACR acrosin
ADAM17 ADAM metallopeptidase domain 17
AGBL2 ATP/GTP binding protein-like 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKNA AT-hook transcription factor
ALB albumin
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APOH apolipoprotein H (beta-2-glycoprotein I)
BAK1 BCL2-antagonist/killer 1
BTBD8 BTB (POZ) domain containing 8
BTG3 BTG family, member 3
C2 complement component 2
C3 complement component 3
CALR calreticulin
CAST calpastatin
CCR4 chemokine (C-C motif) receptor 4
CD22 CD22 molecule
CD5L CD5 molecule-like
CD69 CD69 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFH complement factor H
CFHR1 complement factor H-related 1
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CMKLR1 chemerin chemokine-like receptor 1
COX2
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR5 chemokine (C-X-C motif) receptor 5
CYBB cytochrome b-245, beta polypeptide
DES desmin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EDNRA endothelin receptor type A
ELANE elastase, neutrophil expressed
EMP1 epithelial membrane protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM167A family with sequence similarity 167, member A
FAS Fas cell surface death receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FOLR2 folate receptor 2 (fetal)
FRZB frizzled-related protein
FSTL1 follistatin-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCA grancalcin, EF-hand calcium binding protein
GOLGB1 golgin B1
GPR151 G protein-coupled receptor 151
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRAP2 GRB2-related adaptor protein 2
GRK6 G protein-coupled receptor kinase 6
GRN granulin
GTF2I general transcription factor IIi
HFE hemochromatosis
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
ICOS inducible T-cell co-stimulator
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL32 interleukin 32
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
INHBA inhibin, beta A
IRAK3 interleukin-1 receptor-associated kinase 3
IRF5 interferon regulatory factor 5
ISG20 interferon stimulated exonuclease gene 20kDa
KDR kinase insert domain receptor
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT20 keratin 20, type I
LCN2 lipocalin 2
LEP leptin
LGALS8 lectin, galactoside-binding, soluble, 8
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LPAR3 lysophosphatidic acid receptor 3
LUM lumican
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MEFV Mediterranean fever
MGP matrix Gla protein
MRGPRX1 MAS-related GPR, member X1
MRGPRX3 MAS-related GPR, member X3
MRGPRX4 MAS-related GPR, member X4
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTX1 metaxin 1
NCF1 neutrophil cytosolic factor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRP1 neuropilin 1
NT5C1A 5'-nucleotidase, cytosolic IA
NT5E 5'-nucleotidase, ecto (CD73)
OXER1 oxoeicosanoid (OXE) receptor 1
PADI4 peptidyl arginine deiminase, type IV
PDLIM7 PDZ and LIM domain 7 (enigma)
PLAU plasminogen activator, urokinase
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR1G RNA polymerase I subunit G
POMC proopiomelanocortin
PRC1 protein regulator of cytokinesis 1
PRF1 perforin 1 (pore forming protein)
PRL prolactin
PSIP1 PC4 and SFRS1 interacting protein 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM45 RNA binding motif protein 45
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RO60 Ro60, Y RNA binding protein
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SELL selectin L
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SOAT1 sterol O-acyltransferase 1
SOX13 SRY (sex determining region Y)-box 13
SPTA1 spectrin, alpha, erythrocytic 1
TG thyroglobulin
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNP1 transition protein 1 (during histone to protamine replacement)
TPMT thiopurine S-methyltransferase
TPO thyroid peroxidase
TRAF1 TNF receptor-associated factor 1
TRIM21 tripartite motif containing 21
TTN titin
TWIST1 twist family bHLH transcription factor 1
TYK2 tyrosine kinase 2
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIL1 villin 1
VIP vasoactive intestinal peptide
WNT5A wingless-type MMTV integration site family, member 5A
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6