Rho protein signal transduction Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. (Gene Ontology, GO_0007266)
External Link http://amigo.geneontology.org/amigo/term/GO:0007266
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Genes

56 genes participating in the Rho protein signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
ADRA2A adrenoceptor alpha 2A
AGTR1 angiotensin II receptor, type 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP27 Rho GTPase activating protein 27
ARHGAP29 Rho GTPase activating protein 29
ARHGAP35 Rho GTPase activating protein 35
ARHGAP4 Rho GTPase activating protein 4
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
C15ORF62 chromosome 15 open reading frame 62
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH13 cadherin 13
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
COL1A2 collagen, type I, alpha 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
EPS8L3 EPS8-like 3
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
LIMK1 LIM domain kinase 1
LRRK2 leucine-rich repeat kinase 2
MYO9B myosin IXB
NGFR nerve growth factor receptor
NTN1 netrin 1
PDPN podoplanin
PHACTR4 phosphatase and actin regulator 4
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
RACGAP1 Rac GTPase activating protein 1
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOD ras homolog family member D
RHOG ras homolog family member G
RIPOR1 RHO family interacting cell polarization regulator 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROPN1B rhophilin associated tail protein 1B
RTKN rhotekin
SHTN1 shootin 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome