| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ribociclib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ribociclib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.129186 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.127698 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.118723 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0733482 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.072962 |
| CANX | calnexin | 0.0696 |
| AHI1 | Abelson helper integration site 1 | 0.0681652 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0613967 |
| RNF149 | ring finger protein 149 | 0.0493585 |
| PHF3 | PHD finger protein 3 | 0.04925 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0455462 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0454995 |
| GOLGA4 | golgin A4 | 0.0440604 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0432101 |
| OGA | O-GlcNAcase | 0.0428025 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.042003 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.041565 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0397372 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.039354 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.038058 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0372489 |
| H1-0 | H1.0 linker histone | 0.0371446 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0370647 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0367582 |
| SEC24D | SEC24 family member D | 0.0365661 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0352765 |
| FNIP1 | folliculin interacting protein 1 | 0.0352203 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0348898 |
| UBAC2 | UBA domain containing 2 | 0.0347647 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0344268 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340199 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0338331 |
| YEATS2 | YEATS domain containing 2 | 0.032447 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0324292 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0320133 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0314376 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0308275 |
| AHNAK | AHNAK nucleoprotein | 0.0305163 |
| NF1 | neurofibromin 1 | 0.0302008 |
| RBM39 | RNA binding motif protein 39 | 0.0299874 |
| SBF2 | SET binding factor 2 | 0.0296431 |
| PTEN | phosphatase and tensin homolog | 0.0294951 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0292033 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0287475 |
| HELZ | helicase with zinc finger | 0.028721 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0286628 |
| HDLBP | high density lipoprotein binding protein | 0.0283635 |
| RNF43 | ring finger protein 43 | 0.0283223 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0282483 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0281023 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0279776 |
| RBM26 | RNA binding motif protein 26 | 0.0278725 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0273288 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0268095 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0265495 |
| COG6 | component of oligomeric golgi complex 6 | 0.0265494 |
| PRELID2 | PRELI domain containing 2 | 0.0263412 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.0259244 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.025721 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0256544 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0252965 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0252592 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.02507 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0248455 |
| METTL15 | methyltransferase like 15 | 0.0246579 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0245688 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0244733 |
| ERP44 | endoplasmic reticulum protein 44 | 0.0243311 |
| DIAPH3 | diaphanous-related formin 3 | 0.0242919 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.024257 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.024141 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0241335 |
| TMEM39A | transmembrane protein 39A | 0.0239907 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0238889 |
| AGR2 | anterior gradient 2 | 0.0237976 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.0233939 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0233713 |
| USP3 | ubiquitin specific peptidase 3 | 0.0233593 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0232727 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0232299 |
| ZNF638 | zinc finger protein 638 | 0.0231977 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0231895 |
| TRIM2 | tripartite motif containing 2 | 0.0230794 |
| GOLGA2 | golgin A2 | 0.0230785 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 0.0227689 |
| GRAMD2B | GRAM domain containing 2B | 0.0227544 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0226158 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0225092 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0224716 |
| FDPS | farnesyl diphosphate synthase | 0.0224113 |
| DENND4C | DENN/MADD domain containing 4C | 0.0223062 |
| SUCO | SUN domain containing ossification factor | 0.0222528 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0220559 |
| SFXN1 | sideroflexin 1 | 0.0220467 |
| TAOK1 | TAO kinase 1 | 0.0220209 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.021869 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0217471 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0215642 |
| CLTC | clathrin, heavy chain (Hc) | 0.0214644 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0214406 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.209661 |
| EGR1 | early growth response 1 | -0.163352 |
| LMO7 | LIM domain 7 | -0.15761 |
| ANXA2 | annexin A2 | -0.13561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117479 |
| LCN2 | lipocalin 2 | -0.10534 |
| RNF213 | ring finger protein 213 | -0.105299 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.105237 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0956799 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0941015 |
| AREG | amphiregulin | -0.09262 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0900016 |
| MYO1E | myosin IE | -0.086869 |
| INTS6 | integrator complex subunit 6 | -0.0747331 |
| MX1 | MX dynamin-like GTPase 1 | -0.0742574 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0733307 |
| EZR | ezrin | -0.0712567 |
| FTL | ferritin, light polypeptide | -0.0707203 |
| TJP1 | tight junction protein 1 | -0.0699971 |
| MX2 | MX dynamin-like GTPase 2 | -0.0698092 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0693822 |
| PKM | pyruvate kinase, muscle | -0.0676587 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0663453 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0651618 |
| RIGI | RNA sensor RIG-I | -0.0639508 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0638849 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0623954 |
| SP100 | SP100 nuclear antigen | -0.0614283 |
| JUN | jun proto-oncogene | -0.0607881 |
| VCL | vinculin | -0.0599657 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0557262 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0536517 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0530499 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0527092 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0526566 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0525418 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0520371 |
| ITGA6 | integrin, alpha 6 | -0.0518645 |
| PERP | PERP, TP53 apoptosis effector | -0.0518004 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0517274 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0510543 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0510019 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0509363 |
| ACTG1 | actin gamma 1 | -0.0499842 |
| VMP1 | vacuole membrane protein 1 | -0.0490943 |
| MCL1 | myeloid cell leukemia 1 | -0.0489992 |
| CCNL1 | cyclin L1 | -0.0486675 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0486399 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0479233 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0474859 |
| MT2A | metallothionein 2A | -0.047054 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0466149 |
| POTEF | POTE ankyrin domain family, member F | -0.0460134 |
| ERBIN | erbb2 interacting protein | -0.0458632 |
| IRF1 | interferon regulatory factor 1 | -0.0451891 |
| TMSB10 | thymosin beta 10 | -0.044459 |
| NCKAP5 | NCK-associated protein 5 | -0.0441592 |
| PLSCR2 | phospholipid scramblase 2 | -0.0432966 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0426941 |
| EFNB2 | ephrin-B2 | -0.0418202 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0412372 |
| CST3 | cystatin C | -0.0410466 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0401952 |
| DIAPH1 | diaphanous-related formin 1 | -0.0389979 |
| RPL23 | ribosomal protein L23 | -0.0385214 |
| CLDN4 | claudin 4 | -0.038317 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0381964 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0381203 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.037761 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0374835 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0374251 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0368339 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0365026 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0353921 |
| TMC5 | transmembrane channel-like 5 | -0.0347139 |
| PLSCR1 | phospholipid scramblase 1 | -0.0344987 |
| NABP1 | nucleic acid binding protein 1 | -0.0341613 |
| STK24 | serine/threonine kinase 24 | -0.0339528 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0337638 |
| RPL35A | ribosomal protein L35a | -0.0333484 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0330074 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.032892 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0328481 |
| SMAD3 | SMAD family member 3 | -0.0325927 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0324782 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322114 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0322113 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0318729 |
| HLA-B | major histocompatibility complex, class I, B | -0.0313575 |
| POU2F2 | POU class 2 homeobox 2 | -0.0309049 |
| TPI1 | triosephosphate isomerase 1 | -0.0307403 |
| IRS2 | insulin receptor substrate 2 | -0.0306097 |
| RPS19 | ribosomal protein S19 | -0.0306037 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0305776 |
| BCL2L1 | BCL2-like 1 | -0.0304807 |
| RPL31 | ribosomal protein L31 | -0.0301029 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0300838 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0300733 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0300421 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0297116 |
