| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ribociclib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ribociclib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.128077 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.110757 |
| TXNRD1 | thioredoxin reductase 1 | 0.100938 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.079451 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0773291 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0749378 |
| CANX | calnexin | 0.0705434 |
| CD44 | CD44 molecule (Indian blood group) | 0.0698605 |
| MT2A | metallothionein 2A | 0.0689599 |
| AHNAK | AHNAK nucleoprotein | 0.0689496 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0634969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0599857 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0595967 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0562638 |
| SRGN | serglycin | 0.0551056 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0533011 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0531143 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0528027 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0511581 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0507106 |
| RAI1 | retinoic acid induced 1 | 0.0503419 |
| RPL3 | ribosomal protein L3 | 0.0474996 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0468228 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0458549 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0448444 |
| CAPRIN2 | caprin family member 2 | 0.0443111 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0431599 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0419289 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0409502 |
| DST | dystonin | 0.0405611 |
| BMERB1 | bMERB domain containing 1 | 0.0405438 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0398142 |
| VIM | vimentin | 0.0392989 |
| EMP1 | epithelial membrane protein 1 | 0.0392251 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0391765 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0386053 |
| EZR | ezrin | 0.0384041 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0382154 |
| EREG | epiregulin | 0.0376535 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0374063 |
| LDHA | lactate dehydrogenase A | 0.0373118 |
| USP34 | ubiquitin specific peptidase 34 | 0.0367059 |
| TMSB4X | thymosin beta 4, X-linked | 0.0365473 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0361859 |
| HDLBP | high density lipoprotein binding protein | 0.0357092 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.035536 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0346357 |
| TMEM41B | transmembrane protein 41B | 0.0343255 |
| SDC4 | syndecan 4 | 0.0341581 |
| CEP170 | centrosomal protein 170kDa | 0.0340994 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0337885 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0335287 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0331817 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0329602 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0327037 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0326342 |
| OGA | O-GlcNAcase | 0.0323518 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0320622 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0315772 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0314428 |
| MKI67 | marker of proliferation Ki-67 | 0.0310173 |
| APP | amyloid beta (A4) precursor protein | 0.0306984 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0303145 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0302424 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.029875 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0298053 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0294945 |
| TPM4 | tropomyosin 4 | 0.0294484 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0292665 |
| PYGB | phosphorylase, glycogen; brain | 0.0289462 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0289167 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0281406 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0280329 |
| FLNB | filamin B, beta | 0.0278646 |
| CFDP1 | craniofacial development protein 1 | 0.0274904 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0274491 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0272558 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0270128 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268548 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0267998 |
| RPL4 | ribosomal protein L4 | 0.0267359 |
| KIAA1958 | KIAA1958 | 0.0262845 |
| MT1E | metallothionein 1E | 0.0262574 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0260399 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0259761 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0258146 |
| RBM39 | RNA binding motif protein 39 | 0.02571 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0256792 |
| RGS4 | regulator of G-protein signaling 4 | 0.025503 |
| DENND5A | DENN/MADD domain containing 5A | 0.0254808 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0254697 |
| POM121 | POM121 transmembrane nucleoporin | 0.0253487 |
| TOP1 | topoisomerase (DNA) I | 0.0253092 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0251134 |
| XPO1 | exportin 1 | 0.0250691 |
| RAB10 | RAB10, member RAS oncogene family | 0.0248869 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0248793 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.024523 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0244542 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0243183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190168 |
| POTEF | POTE ankyrin domain family, member F | -0.153013 |
| TMSB10 | thymosin beta 10 | -0.115013 |
| FTL | ferritin, light polypeptide | -0.065045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0621903 |
| EGR1 | early growth response 1 | -0.0620302 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.061398 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0574454 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0543628 |
| CCNL1 | cyclin L1 | -0.0469582 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0459091 |
| B2M | beta-2-microglobulin | -0.0455085 |
| TXNIP | thioredoxin interacting protein | -0.0440544 |
| HMGA1 | high mobility group AT-hook 1 | -0.0401602 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0400253 |
| RPS19 | ribosomal protein S19 | -0.0389606 |
| RPL12 | ribosomal protein L12 | -0.0358707 |
| TP63 | tumor protein p63 | -0.0351011 |
| RPS12 | ribosomal protein S12 | -0.0349706 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0342426 |
| PLK2 | polo-like kinase 2 | -0.0336552 |
| ANXA1 | annexin A1 | -0.0335913 |
| ENO1 | enolase 1, (alpha) | -0.033291 |
| CADM2 | cell adhesion molecule 2 | -0.0330319 |
| RPS2 | ribosomal protein S2 | -0.0322076 |
| RPL36 | ribosomal protein L36 | -0.0321654 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0296744 |
| EFNA5 | ephrin-A5 | -0.0294937 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0280893 |
| HDAC9 | histone deacetylase 9 | -0.02801 |
| NDRG1 | N-myc downstream regulated 1 | -0.0277115 |
| CALR | calreticulin | -0.027528 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0272864 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0268878 |
| HLA-B | major histocompatibility complex, class I, B | -0.0267638 |
| TPI1 | triosephosphate isomerase 1 | -0.0260583 |
| RPL31 | ribosomal protein L31 | -0.0260482 |
| UBC | ubiquitin C | -0.025944 |
| RPS3 | ribosomal protein S3 | -0.025712 |
| RPL35A | ribosomal protein L35a | -0.0252115 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0247413 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0244696 |
| PCDH1 | protocadherin 1 | -0.0241891 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0236837 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0235506 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0234223 |
| PFN1 | profilin 1 | -0.023236 |
| TNS3 | tensin 3 | -0.0230055 |
| HLA-A | major histocompatibility complex, class I, A | -0.0228074 |
| WASF2 | WAS protein family, member 2 | -0.0225068 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0224031 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.021545 |
| BSG | basigin (Ok blood group) | -0.021499 |
| RACK1 | receptor for activated C kinase 1 | -0.0214163 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0212705 |
| ARF6 | ADP-ribosylation factor 6 | -0.0212214 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0205972 |
| RPL35 | ribosomal protein L35 | -0.020564 |
| RPS23 | ribosomal protein S23 | -0.0203703 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0203696 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0199097 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0197583 |
| JUN | jun proto-oncogene | -0.0194916 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0194581 |
| YBX1 | Y box binding protein 1 | -0.0192356 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.019131 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0191024 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0190637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0190236 |
| RPS14 | ribosomal protein S14 | -0.0189407 |
| FAM162A | family with sequence similarity 162, member A | -0.0189062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0186617 |
| VEGFA | vascular endothelial growth factor A | -0.0186443 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0185809 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.018215 |
| DPH6 | diphthamine biosynthesis 6 | -0.0182148 |
| SFTPA2 | surfactant protein A2 | -0.0175782 |
| RPL23 | ribosomal protein L23 | -0.0174819 |
| VMP1 | vacuole membrane protein 1 | -0.0171517 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0169628 |
| RPS6 | ribosomal protein S6 | -0.0167318 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0167154 |
| EGFR | epidermal growth factor receptor | -0.0165508 |
| RPL21 | ribosomal protein L21 | -0.0161942 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0161784 |
| EPHA4 | EPH receptor A4 | -0.0161704 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0161609 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0160467 |
| ASTN2 | astrotactin 2 | -0.0159867 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0158515 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0157819 |
| TSC22D2 | TSC22 domain family, member 2 | -0.015756 |
| SNX3 | sorting nexin 3 | -0.0156661 |
| RPS25 | ribosomal protein S25 | -0.0156318 |
| RPL7A | ribosomal protein L7a | -0.0155871 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0155323 |
| TAPBP | TAP binding protein (tapasin) | -0.0155285 |
| PLIN2 | perilipin 2 | -0.0153472 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0153231 |
| ATN1 | atrophin 1 | -0.0152123 |
