| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ribociclib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ribociclib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.140965 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.073321 |
| MT2A | metallothionein 2A | 0.06016 |
| RPS3 | ribosomal protein S3 | 0.0569373 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0544879 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0514766 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0514635 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0507511 |
| PTMA | prothymosin, alpha | 0.0484089 |
| RPL37A | ribosomal protein L37a | 0.0481422 |
| RPLP1 | ribosomal protein, large, P1 | 0.0466374 |
| FAM13A | family with sequence similarity 13, member A | 0.0466349 |
| RUNX1 | runt-related transcription factor 1 | 0.0451965 |
| NGLY1 | N-glycanase 1 | 0.0437833 |
| RPS8 | ribosomal protein S8 | 0.0433505 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.043241 |
| TMEM165 | transmembrane protein 165 | 0.0420224 |
| RPS24 | ribosomal protein S24 | 0.0409408 |
| OGA | O-GlcNAcase | 0.0394068 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0387522 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0373451 |
| RPS12 | ribosomal protein S12 | 0.0367771 |
| RPL35A | ribosomal protein L35a | 0.0365849 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.036199 |
| HELZ | helicase with zinc finger | 0.0358181 |
| SPAG9 | sperm associated antigen 9 | 0.0353736 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0353678 |
| RPS25 | ribosomal protein S25 | 0.034777 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0346215 |
| ARRDC3 | arrestin domain containing 3 | 0.03457 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0344103 |
| RPS6 | ribosomal protein S6 | 0.0337492 |
| KCMF1 | potassium channel modulatory factor 1 | 0.033552 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0326368 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0323632 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0318806 |
| RPLP0 | ribosomal protein, large, P0 | 0.0314986 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0312384 |
| UVRAG | UV radiation resistance associated | 0.0308856 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0296873 |
| MATR3 | matrin 3 | 0.0293324 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0290317 |
| ZNF292 | zinc finger protein 292 | 0.0289339 |
| RPL5 | ribosomal protein L5 | 0.0288792 |
| SEC61G | Sec61 gamma subunit | 0.028051 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0279751 |
| RPL9 | ribosomal protein L9 | 0.0271851 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0270387 |
| WDR45B | WD repeat domain 45B | 0.0261746 |
| GPHN | gephyrin | 0.025976 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0258929 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0249544 |
| RPL30 | ribosomal protein L30 | 0.024806 |
| RPL34 | ribosomal protein L34 | 0.0240292 |
| ZFR | zinc finger RNA binding protein | 0.0239737 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0239579 |
| USP34 | ubiquitin specific peptidase 34 | 0.0238932 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0238618 |
| RPL7 | ribosomal protein L7 | 0.0237684 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0237617 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0236435 |
| MXI1 | MAX interactor 1, dimerization protein | 0.023642 |
| RPL12 | ribosomal protein L12 | 0.0235736 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0232765 |
| SQSTM1 | sequestosome 1 | 0.0232116 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0231355 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0231324 |
| MAP7 | microtubule-associated protein 7 | 0.023065 |
| RPS23 | ribosomal protein S23 | 0.0229122 |
| RPL26 | ribosomal protein L26 | 0.0228914 |
| DENND4A | DENN/MADD domain containing 4A | 0.022888 |
| RPL37 | ribosomal protein L37 | 0.0226321 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0226017 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0224726 |
| RPL23 | ribosomal protein L23 | 0.0223675 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0221674 |
| PDE8A | phosphodiesterase 8A | 0.0220037 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0219324 |
| RNF24 | ring finger protein 24 | 0.0219125 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.02148 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0214754 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0212588 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0209712 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0207661 |
| NUP58 | nucleoporin 58 | 0.0207536 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0205965 |
| TOP1 | topoisomerase (DNA) I | 0.0205858 |
| MED13 | mediator complex subunit 13 | 0.0204453 |
| RPL31 | ribosomal protein L31 | 0.020362 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0202371 |
| RPL11 | ribosomal protein L11 | 0.020188 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0201699 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0201084 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0200635 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200003 |
| RPS17 | ribosomal protein S17 | 0.0199884 |
| RPS29 | ribosomal protein S29 | 0.0197596 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0197585 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0197035 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0196518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.334313 |
| LMO7 | LIM domain 7 | -0.141582 |
| LAMC2 | laminin, gamma 2 | -0.12635 |
| ASPH | aspartate beta-hydroxylase | -0.114407 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.102002 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0982176 |
| LAMA4 | laminin, alpha 4 | -0.09223 |
| OSMR | oncostatin M receptor | -0.0854854 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0824366 |
| SCEL | sciellin | -0.0722202 |
| LDHA | lactate dehydrogenase A | -0.0711484 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0710141 |
| AHNAK | AHNAK nucleoprotein | -0.0710094 |
| TXNRD1 | thioredoxin reductase 1 | -0.0683424 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0672053 |
| DSPP | dentin sialophosphoprotein | -0.0656575 |
| ACTG1 | actin gamma 1 | -0.0648369 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0645849 |
| EFNA5 | ephrin-A5 | -0.0621862 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0609599 |
| HDLBP | high density lipoprotein binding protein | -0.0589791 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0576544 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0573379 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0537803 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0530307 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0528376 |
| KRT18 | keratin 18, type I | -0.0524681 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0521584 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.048131 |
| TMSB10 | thymosin beta 10 | -0.0469908 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0469199 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0455257 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0452517 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0452412 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0447736 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0444629 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0404422 |
| KRT7 | keratin 7, type II | -0.0400664 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0392559 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0389839 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0387138 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0383466 |
| MYO1D | myosin ID | -0.0362378 |
| CCND1 | cyclin D1 | -0.0361972 |
| TES | testin LIM domain protein | -0.0359298 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0354213 |
| ANXA2 | annexin A2 | -0.0349037 |
| RIN2 | Ras and Rab interactor 2 | -0.0347398 |
| CUX1 | cut-like homeobox 1 | -0.0339596 |
| FOXP1 | forkhead box P1 | -0.033875 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0336541 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0327049 |
| RNF213 | ring finger protein 213 | -0.0326827 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0324299 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0320696 |
| FLNB | filamin B, beta | -0.0317422 |
| RAB10 | RAB10, member RAS oncogene family | -0.0311799 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.030526 |
| MYOF | myoferlin | -0.0300006 |
| TPM4 | tropomyosin 4 | -0.0293665 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0290122 |
| EHBP1 | EH domain binding protein 1 | -0.0287761 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0286939 |
| EGR1 | early growth response 1 | -0.0282398 |
| DSG2 | desmoglein 2 | -0.0279231 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0279092 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0279073 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0279041 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0275527 |
| VCL | vinculin | -0.0275512 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0274333 |
| MYO1E | myosin IE | -0.0272005 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0268973 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0266374 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0259103 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.025908 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0257899 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.025477 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0250206 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0249831 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0243745 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0243568 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0238398 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0236876 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.023597 |
| PRKCA | protein kinase C, alpha | -0.0235806 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0234206 |
| TNS3 | tensin 3 | -0.0233707 |
| TJP1 | tight junction protein 1 | -0.0232827 |
| MCU | mitochondrial calcium uniporter | -0.0228566 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0228345 |
| CMIP | c-Maf inducing protein | -0.0227708 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0226563 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0226193 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0224773 |
| NTN4 | netrin 4 | -0.0224122 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0219376 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0218106 |
| PLS3 | plastin 3 | -0.0216926 |
| NABP1 | nucleic acid binding protein 1 | -0.021429 |
