| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ribociclib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ribociclib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.117763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.117576 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0935479 |
| B2M | beta-2-microglobulin | 0.0908609 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0749627 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0663114 |
| PTMA | prothymosin, alpha | 0.0569209 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0560367 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0551003 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.05411 |
| ZNF292 | zinc finger protein 292 | 0.0523039 |
| TFG | TRK-fused gene | 0.0522843 |
| SMAD3 | SMAD family member 3 | 0.0500631 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0482153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0479891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.047581 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0454433 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.044484 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0439376 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0427568 |
| FAM13A | family with sequence similarity 13, member A | 0.0424025 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0423439 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0421592 |
| H3-3B | H3.3 histone B | 0.0419158 |
| EFNA5 | ephrin-A5 | 0.0418446 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0416384 |
| RNF24 | ring finger protein 24 | 0.041578 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.041518 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0412487 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0407182 |
| RUNX1 | runt-related transcription factor 1 | 0.040529 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0405185 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0398322 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0397599 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0390841 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0388196 |
| CAVIN1 | caveolae associated protein 1 | 0.0377267 |
| COL1A2 | collagen, type I, alpha 2 | 0.03696 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0369089 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0361353 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0342866 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0341743 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.034024 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0336099 |
| CEP57 | centrosomal protein 57kDa | 0.0335115 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0334103 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0328853 |
| PGK1 | phosphoglycerate kinase 1 | 0.0325342 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0322236 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0320933 |
| STC1 | stanniocalcin 1 | 0.0316101 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0314975 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0312195 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0311083 |
| NEK7 | NIMA-related kinase 7 | 0.0310555 |
| SRSF10 | serine/arginine-rich splicing factor 10 | 0.0308842 |
| PRRC2C | proline-rich coiled-coil 2C | 0.030183 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0299425 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0297844 |
| RYBP | RING1 and YY1 binding protein | 0.0294815 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0293884 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0291485 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0289531 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0289143 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0288409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0287892 |
| FRMD6 | FERM domain containing 6 | 0.0283382 |
| LDHA | lactate dehydrogenase A | 0.0281653 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0279796 |
| TMEM41B | transmembrane protein 41B | 0.0278595 |
| HMGB2 | high mobility group box 2 | 0.0277864 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270916 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0269858 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0266616 |
| SPAG9 | sperm associated antigen 9 | 0.0265802 |
| ANO6 | anoctamin 6 | 0.0265663 |
| ARRDC3 | arrestin domain containing 3 | 0.0263037 |
| COL1A1 | collagen, type I, alpha 1 | 0.0262901 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0262896 |
| CD109 | CD109 molecule | 0.0262778 |
| JUN | jun proto-oncogene | 0.0258895 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0258745 |
| NOP58 | NOP58 ribonucleoprotein | 0.0258211 |
| PARD3 | par-3 family cell polarity regulator | 0.0256687 |
| STK17A | serine/threonine kinase 17a | 0.0252146 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0251721 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251396 |
| AHNAK | AHNAK nucleoprotein | 0.0251338 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0250707 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0248567 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0248443 |
| EMP1 | epithelial membrane protein 1 | 0.0245682 |
| RHEB | Ras homolog enriched in brain | 0.0245424 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0243779 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0240441 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0239692 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0239604 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0239604 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0239159 |
| RPLP2 | ribosomal protein, large, P2 | 0.0238999 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.185364 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0761222 |
| VIM | vimentin | -0.0739958 |
| EGFR | epidermal growth factor receptor | -0.0607818 |
| ASPH | aspartate beta-hydroxylase | -0.0545066 |
| FTL | ferritin, light polypeptide | -0.0534167 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0531911 |
| DSTN | destrin (actin depolymerizing factor) | -0.0517685 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0464759 |
| C1D | C1D nuclear receptor corepressor | -0.0442584 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0431037 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0419179 |
| ECE1 | endothelin converting enzyme 1 | -0.0409439 |
| INTS6 | integrator complex subunit 6 | -0.0407243 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0406537 |
| FLNA | filamin A, alpha | -0.0398396 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0389815 |
| SEC24D | SEC24 family member D | -0.0381943 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0381542 |
| ITGAV | integrin, alpha V | -0.0372512 |
| NDRG1 | N-myc downstream regulated 1 | -0.0362333 |
| RAB10 | RAB10, member RAS oncogene family | -0.0360348 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0355352 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0354721 |
| CADM1 | cell adhesion molecule 1 | -0.0352895 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0331202 |
| MSN | moesin | -0.0330359 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0330292 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0328526 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0323289 |
| ACTG1 | actin gamma 1 | -0.0319488 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0314488 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0309045 |
| HLA-A | major histocompatibility complex, class I, A | -0.0306934 |
| GLG1 | golgi glycoprotein 1 | -0.0306591 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0305977 |
| PCBP2 | poly(rC) binding protein 2 | -0.0303073 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.030217 |
| CLIC4 | chloride intracellular channel 4 | -0.0297985 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0296257 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0293367 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0292731 |
| HMGA2 | high mobility group AT-hook 2 | -0.029237 |
| ERBIN | erbb2 interacting protein | -0.0289509 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.028897 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0282723 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0282675 |
| PKM | pyruvate kinase, muscle | -0.0281484 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0276514 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0275966 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.026945 |
| TLN1 | talin 1 | -0.0268211 |
| MT2A | metallothionein 2A | -0.0268113 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268077 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0265271 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0262898 |
| CUL3 | cullin 3 | -0.0261848 |
| TMSB10 | thymosin beta 10 | -0.0261074 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0261054 |
| TBCA | tubulin folding cofactor A | -0.0259803 |
| CALD1 | caldesmon 1 | -0.025861 |
| PRDX5 | peroxiredoxin 5 | -0.0255959 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0255681 |
| VEGFA | vascular endothelial growth factor A | -0.0254918 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0253856 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0252119 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0250852 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0250796 |
| CA12 | carbonic anhydrase XII | -0.0250499 |
| JAK1 | Janus kinase 1 | -0.0250307 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.024612 |
| PGM3 | phosphoglucomutase 3 | -0.0242149 |
| MED4 | mediator complex subunit 4 | -0.0242002 |
| RPN2 | ribophorin II | -0.023796 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0237956 |
| RND3 | Rho family GTPase 3 | -0.0235338 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0234321 |
| RBM15 | RNA binding motif protein 15 | -0.0233288 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0229726 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0229539 |
| TPM4 | tropomyosin 4 | -0.0229537 |
| HMGA1 | high mobility group AT-hook 1 | -0.0228041 |
| RTN4 | reticulon 4 | -0.0227654 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0225502 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.022505 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0224622 |
| RPS8 | ribosomal protein S8 | -0.0224035 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0220772 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0220253 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0219972 |
| POTEF | POTE ankyrin domain family, member F | -0.0218255 |
| COL6A3 | collagen, type VI, alpha 3 | -0.021765 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0216861 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0216732 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -0.0216511 |
| CDH13 | cadherin 13 | -0.0215124 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.0214799 |
| FAM107B | family with sequence similarity 107, member B | -0.0212325 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0211908 |
| TSPAN9 | tetraspanin 9 | -0.0211193 |
