| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ribociclib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ribociclib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0737034 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0620513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0521414 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0470341 |
| SPAG9 | sperm associated antigen 9 | 0.046535 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.045963 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0452499 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0447033 |
| KIAA1958 | KIAA1958 | 0.0417494 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0415656 |
| VIM | vimentin | 0.040254 |
| SGO2 | shugoshin 2 | 0.0377363 |
| SNX14 | sorting nexin 14 | 0.0376047 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0374622 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0371013 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0367291 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0357537 |
| CANX | calnexin | 0.0356914 |
| KIAA1328 | KIAA1328 | 0.0352862 |
| ABI2 | abl-interactor 2 | 0.035276 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0351118 |
| ATM | ATM serine/threonine kinase | 0.0348348 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0342669 |
| OLA1 | Obg-like ATPase 1 | 0.0339988 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0336305 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0329589 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0327808 |
| MKI67 | marker of proliferation Ki-67 | 0.0325405 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0311256 |
| ECT2 | epithelial cell transforming 2 | 0.0310856 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0308588 |
| OGA | O-GlcNAcase | 0.0306964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0306848 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0297383 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0294252 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0292179 |
| TUBB | tubulin, beta class I | 0.0286986 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0285153 |
| FMN1 | formin 1 | 0.0283392 |
| ZFR | zinc finger RNA binding protein | 0.0283012 |
| ZNF292 | zinc finger protein 292 | 0.0279684 |
| NKTR | natural killer cell triggering receptor | 0.0278761 |
| RBM39 | RNA binding motif protein 39 | 0.0275884 |
| AHNAK | AHNAK nucleoprotein | 0.0274469 |
| AXL | AXL receptor tyrosine kinase | 0.0270652 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0268563 |
| USP3 | ubiquitin specific peptidase 3 | 0.0266099 |
| PGK1 | phosphoglycerate kinase 1 | 0.0265582 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0264497 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0262257 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0260431 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0258652 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0257724 |
| HJURP | Holliday junction recognition protein | 0.0257261 |
| SMYD3 | SET and MYND domain containing 3 | 0.0257161 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0256513 |
| CDC73 | cell division cycle 73 | 0.0251582 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0251546 |
| RANBP17 | RAN binding protein 17 | 0.0249765 |
| PHF21A | PHD finger protein 21A | 0.0249074 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0248264 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0245525 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.02433 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0241304 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0241293 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0240675 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0240547 |
| GOLT1B | golgi transport 1B | 0.0238159 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0236894 |
| ANLN | anillin, actin binding protein | 0.0236653 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0236234 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0234427 |
| TMEM135 | transmembrane protein 135 | 0.02339 |
| PRR11 | proline rich 11 | 0.0233893 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0232698 |
| ZNF670 | zinc finger protein 670 | 0.0232325 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.023176 |
| CEP192 | centrosomal protein 192kDa | 0.0231157 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.023107 |
| GPR107 | G protein-coupled receptor 107 | 0.023074 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0229329 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0227765 |
| CBFB | core-binding factor, beta subunit | 0.0227625 |
| DST | dystonin | 0.0226533 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0226317 |
| FAM168B | family with sequence similarity 168, member B | 0.0226266 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0226001 |
| TMEM123 | transmembrane protein 123 | 0.022591 |
| MATR3 | matrin 3 | 0.0225242 |
| NBAS | neuroblastoma amplified sequence | 0.0224943 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0224863 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.022238 |
| TPX2 | TPX2, microtubule-associated | 0.0222251 |
| CDK13 | cyclin-dependent kinase 13 | 0.0221716 |
| SNX9 | sorting nexin 9 | 0.0221454 |
| ZNF654 | zinc finger protein 654 | 0.0221222 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0220137 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.022013 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0220035 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0219715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.436086 |
| TMSB10 | thymosin beta 10 | -0.117958 |
| MT2A | metallothionein 2A | -0.0916876 |
| FTL | ferritin, light polypeptide | -0.0763901 |
| EGR1 | early growth response 1 | -0.0661147 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0660146 |
| PKM | pyruvate kinase, muscle | -0.0656834 |
| POTEF | POTE ankyrin domain family, member F | -0.0566517 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0560232 |
| SQSTM1 | sequestosome 1 | -0.0554957 |
| CD44 | CD44 molecule (Indian blood group) | -0.0524669 |
| UBC | ubiquitin C | -0.0516182 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0514159 |
| ENO1 | enolase 1, (alpha) | -0.0468253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0462164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0460363 |
| RPS13 | ribosomal protein S13 | -0.042221 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0406211 |
| RPL23 | ribosomal protein L23 | -0.0392277 |
| RPL37A | ribosomal protein L37a | -0.0389494 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0385734 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0374823 |
| RPL19 | ribosomal protein L19 | -0.0374188 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369011 |
| B2M | beta-2-microglobulin | -0.0368913 |
| RPL28 | ribosomal protein L28 | -0.0366118 |
| BRD4 | bromodomain containing 4 | -0.0361753 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0357485 |
| RPS27A | ribosomal protein S27a | -0.0356643 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0355415 |
| BRD2 | bromodomain containing 2 | -0.0355064 |
| RPS29 | ribosomal protein S29 | -0.0352715 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0347616 |
| RPS12 | ribosomal protein S12 | -0.0345658 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0327401 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.032717 |
| ANXA1 | annexin A1 | -0.0326669 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0321463 |
| GOLGB1 | golgin B1 | -0.0316607 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0312991 |
| S100A9 | S100 calcium binding protein A9 | -0.0306482 |
| ANGPTL4 | angiopoietin-like 4 | -0.0305666 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0303925 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0303423 |
| RPS6 | ribosomal protein S6 | -0.0303039 |
| RPL31 | ribosomal protein L31 | -0.0299465 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0298666 |
| RPS10 | ribosomal protein S10 | -0.0296376 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0290145 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0289326 |
| RPS15 | ribosomal protein S15 | -0.0282078 |
| RIOK3 | RIO kinase 3 | -0.0274175 |
| MCL1 | myeloid cell leukemia 1 | -0.0269823 |
| RPL5 | ribosomal protein L5 | -0.0266984 |
| RPS8 | ribosomal protein S8 | -0.0264938 |
| TUBB4B | tubulin, beta 4B class IVb | -0.026116 |
| RPS17 | ribosomal protein S17 | -0.0259927 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0258028 |
| YBX1 | Y box binding protein 1 | -0.0257792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0253854 |
| RPLP1 | ribosomal protein, large, P1 | -0.0249799 |
| PCBP2 | poly(rC) binding protein 2 | -0.0249072 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0248356 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0248028 |
| S100A6 | S100 calcium binding protein A6 | -0.0246881 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.024643 |
| USP15 | ubiquitin specific peptidase 15 | -0.0245692 |
| RPLP0 | ribosomal protein, large, P0 | -0.0245535 |
| HM13 | histocompatibility (minor) 13 | -0.0245069 |
| PFN1 | profilin 1 | -0.0242271 |
| RPS3 | ribosomal protein S3 | -0.0241014 |
| CLIC4 | chloride intracellular channel 4 | -0.0239255 |
| RPL37 | ribosomal protein L37 | -0.0237732 |
| RPL27A | ribosomal protein L27a | -0.0234271 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0233937 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0232863 |
| RPL7A | ribosomal protein L7a | -0.0232825 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0230243 |
| RPL15 | ribosomal protein L15 | -0.0229594 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0228337 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0227745 |
| RPL26 | ribosomal protein L26 | -0.0226744 |
| RACK1 | receptor for activated C kinase 1 | -0.0225924 |
| INTS6 | integrator complex subunit 6 | -0.0225696 |
| JUN | jun proto-oncogene | -0.0225394 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0222706 |
| UBAP2 | ubiquitin associated protein 2 | -0.0220881 |
| RPL36 | ribosomal protein L36 | -0.0220553 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.021655 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0215722 |
| RPLP2 | ribosomal protein, large, P2 | -0.0214636 |
| USP53 | ubiquitin specific peptidase 53 | -0.0214254 |
| NLK | nemo-like kinase | -0.0213372 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0207786 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0207025 |
| TOP1 | topoisomerase (DNA) I | -0.0206958 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0206775 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0206088 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0206047 |
| RPS27 | ribosomal protein S27 | -0.0205097 |
