| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rifaximin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.113787 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0318928 |
| NAV2 | neuron navigator 2 | 0.0291619 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258545 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0228438 |
| STC1 | stanniocalcin 1 | 0.0223447 |
| OGA | O-GlcNAcase | 0.0222871 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0212098 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.02094 |
| OPTN | optineurin | 0.0196053 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0187285 |
| ATP13A3 | ATPase type 13A3 | 0.0186348 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0171598 |
| MYO9A | myosin IXA | 0.017016 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0164162 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0162789 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0162244 |
| SQSTM1 | sequestosome 1 | 0.0159026 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0158951 |
| SEPTIN9 | septin 9 | 0.0158865 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0156998 |
| FNIP1 | folliculin interacting protein 1 | 0.0156324 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0154343 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0154065 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0153565 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0148786 |
| HIP1 | huntingtin interacting protein 1 | 0.0147535 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0146896 |
| ARRDC3 | arrestin domain containing 3 | 0.0144023 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0143981 |
| GPC6 | glypican 6 | 0.0142511 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0141179 |
| FBN1 | fibrillin 1 | 0.0141117 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0140396 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0139043 |
| FLNA | filamin A, alpha | 0.0137181 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0136958 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0136764 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.013644 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.013489 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0134563 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0133002 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0130761 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0130227 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0128067 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0127552 |
| MNT | MAX network transcriptional repressor | 0.0126477 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0126002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0125112 |
| ARFGEF3 | ARFGEF family member 3 | 0.0122839 |
| C1D | C1D nuclear receptor corepressor | 0.0122303 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0118218 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0117707 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0115771 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0113465 |
| FLNB | filamin B, beta | 0.0111276 |
| CD109 | CD109 molecule | 0.0110677 |
| ADM | adrenomedullin | 0.011025 |
| SFTPA2 | surfactant protein A2 | 0.0108454 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0107434 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0106784 |
| NGLY1 | N-glycanase 1 | 0.0106015 |
| DTNA | dystrobrevin, alpha | 0.010586 |
| TMOD1 | tropomodulin 1 | 0.0101288 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.010085 |
| KIAA1217 | KIAA1217 | 0.0100012 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0098862 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.00975505 |
| CLSTN2 | calsyntenin 2 | 0.00974239 |
| DENND4A | DENN/MADD domain containing 4A | 0.00970879 |
| GPHN | gephyrin | 0.00970779 |
| COG5 | component of oligomeric golgi complex 5 | 0.00968524 |
| ANK2 | ankyrin 2, neuronal | 0.00964243 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00960009 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00958223 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.00949793 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.00932916 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.00931302 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.00922928 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.00922066 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.00910981 |
| YEATS2 | YEATS domain containing 2 | 0.00898383 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.00898304 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.00894651 |
| LONRF1 | LON peptidase N-terminal domain and ring finger 1 | 0.00887049 |
| KLHL24 | kelch-like family member 24 | 0.00873204 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00869798 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.00867445 |
| RPL7 | ribosomal protein L7 | 0.00864403 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00860469 |
| MTSS1 | metastasis suppressor 1 | 0.00857525 |
| STK10 | serine/threonine kinase 10 | 0.00854492 |
| GOLGA4 | golgin A4 | 0.00847446 |
| SBF2 | SET binding factor 2 | 0.00839582 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00838866 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.00830837 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0082884 |
| LRRC49 | leucine rich repeat containing 49 | 0.0082872 |
| PCGF5 | polycomb group ring finger 5 | 0.008181 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00817896 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.178628 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.136756 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.123466 |
| TMSB10 | thymosin beta 10 | -0.121969 |
| LOX | lysyl oxidase | -0.11951 |
| FN1 | fibronectin 1 | -0.116091 |
| PODXL | podocalyxin-like | -0.113683 |
| MAP1B | microtubule-associated protein 1B | -0.101397 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0953507 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0931295 |
| COL5A1 | collagen, type V, alpha 1 | -0.0897249 |
| CDH13 | cadherin 13 | -0.0864405 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.078483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0752011 |
| S100A10 | S100 calcium binding protein A10 | -0.0723385 |
| NAV1 | neuron navigator 1 | -0.0714371 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0659932 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0652228 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0649668 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0641169 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0628604 |
| PRSS23 | protease, serine, 23 | -0.0623236 |
| AHNAK | AHNAK nucleoprotein | -0.052957 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0519903 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.051458 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0503868 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0500051 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0473409 |
| CSTB | cystatin B (stefin B) | -0.0471444 |
| SUCNR1 | succinate receptor 1 | -0.0462927 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0447454 |
| RIGI | RNA sensor RIG-I | -0.0442617 |
| PLAT | plasminogen activator, tissue | -0.0426286 |
| CD44 | CD44 molecule (Indian blood group) | -0.0404837 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0400547 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0390738 |
| MX2 | MX dynamin-like GTPase 2 | -0.0383614 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0378622 |
| TAGLN2 | transgelin 2 | -0.0376277 |
| POTEF | POTE ankyrin domain family, member F | -0.0375455 |
| DCLK2 | doublecortin-like kinase 2 | -0.0372983 |
| DST | dystonin | -0.0366627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0366113 |
| ANXA2 | annexin A2 | -0.0364359 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0362396 |
| ASPH | aspartate beta-hydroxylase | -0.0361093 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0349813 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.03481 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0343654 |
| FSTL1 | follistatin-like 1 | -0.033117 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0323435 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0317491 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0316696 |
| S100A6 | S100 calcium binding protein A6 | -0.0316295 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0306848 |
| COL5A2 | collagen, type V, alpha 2 | -0.0301168 |
| GLIS3 | GLIS family zinc finger 3 | -0.0295955 |
| LRRC17 | leucine rich repeat containing 17 | -0.0293614 |
| TPM4 | tropomyosin 4 | -0.0291809 |
| EFNA5 | ephrin-A5 | -0.0287405 |
| THBS2 | thrombospondin 2 | -0.0286291 |
| PLXNA2 | plexin A2 | -0.0283002 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.028275 |
| LMNA | lamin A/C | -0.0281354 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0280331 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0279929 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0278263 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0276641 |
| CYTH3 | cytohesin 3 | -0.0272895 |
| MEIS2 | Meis homeobox 2 | -0.0266604 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0263768 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0262475 |
| CUX1 | cut-like homeobox 1 | -0.0260805 |
| TPM1 | tropomyosin 1 (alpha) | -0.0259897 |
| CAVIN1 | caveolae associated protein 1 | -0.025918 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.025912 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0258474 |
| TNS3 | tensin 3 | -0.0256083 |
| RNF213 | ring finger protein 213 | -0.0252064 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0249252 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.024563 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0245041 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0244364 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0243882 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0243468 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0237631 |
| CDK6 | cyclin-dependent kinase 6 | -0.0236423 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0236006 |
| CANX | calnexin | -0.0235901 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0232515 |
| FNDC3A | fibronectin type III domain containing 3A | -0.02324 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0232211 |
| HLA-C | major histocompatibility complex, class I, C | -0.0231822 |
| RUNX1 | runt-related transcription factor 1 | -0.0231768 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0230191 |
| B2M | beta-2-microglobulin | -0.022981 |
| IL7R | interleukin 7 receptor | -0.0229118 |
| S100A11 | S100 calcium binding protein A11 | -0.0227444 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0223191 |
| PKM | pyruvate kinase, muscle | -0.0222864 |
