| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.138617 |
| COL6A3 | collagen, type VI, alpha 3 | 0.125436 |
| ATP13A3 | ATPase type 13A3 | 0.124541 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0986927 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0983565 |
| RPL7 | ribosomal protein L7 | 0.0963521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0929956 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0924151 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0918587 |
| CALR | calreticulin | 0.0910698 |
| CANX | calnexin | 0.0838734 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0824458 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0801384 |
| CADM1 | cell adhesion molecule 1 | 0.0721305 |
| SPAG9 | sperm associated antigen 9 | 0.068365 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0679579 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0603231 |
| TMSB4X | thymosin beta 4, X-linked | 0.0571351 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.054986 |
| PTK2 | protein tyrosine kinase 2 | 0.051428 |
| GOLGA4 | golgin A4 | 0.0514152 |
| OGA | O-GlcNAcase | 0.0511375 |
| AHNAK | AHNAK nucleoprotein | 0.0488553 |
| RASA2 | RAS p21 protein activator 2 | 0.0488401 |
| LDHA | lactate dehydrogenase A | 0.0487692 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0487324 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0484022 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0481649 |
| RPL26 | ribosomal protein L26 | 0.0478863 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0476185 |
| ZNF292 | zinc finger protein 292 | 0.04709 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.046714 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0447159 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0429984 |
| APP | amyloid beta (A4) precursor protein | 0.042719 |
| PGK1 | phosphoglycerate kinase 1 | 0.0422423 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0419216 |
| TFG | TRK-fused gene | 0.041261 |
| SMAD3 | SMAD family member 3 | 0.0411095 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0408085 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0401044 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0399192 |
| RLF | rearranged L-myc fusion | 0.0387331 |
| ADM | adrenomedullin | 0.0386293 |
| RPL23 | ribosomal protein L23 | 0.038302 |
| HELZ | helicase with zinc finger | 0.0378485 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0378111 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0378027 |
| RPL12 | ribosomal protein L12 | 0.0375912 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0374005 |
| USP3 | ubiquitin specific peptidase 3 | 0.0369814 |
| TPM2 | tropomyosin 2 (beta) | 0.0361477 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0355327 |
| PTMA | prothymosin, alpha | 0.0350253 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0346769 |
| FOXJ3 | forkhead box J3 | 0.0342571 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0334237 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0329136 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.032463 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0322266 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0321858 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0321809 |
| RPL35A | ribosomal protein L35a | 0.0321019 |
| ANXA2 | annexin A2 | 0.032096 |
| FMNL2 | formin-like 2 | 0.0313749 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0309667 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0308244 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0308185 |
| MATR3 | matrin 3 | 0.0307871 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0304836 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0303938 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0301873 |
| YBX1 | Y box binding protein 1 | 0.0300731 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0298923 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0298207 |
| FLNA | filamin A, alpha | 0.0297676 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0294885 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0293946 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0292482 |
| HMGB2 | high mobility group box 2 | 0.0287601 |
| WAC | WW domain containing adaptor with coiled-coil | 0.028679 |
| DENND5A | DENN/MADD domain containing 5A | 0.0284214 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283556 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0281999 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0281747 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0280097 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0273926 |
| RBM39 | RNA binding motif protein 39 | 0.0271276 |
| RYK | receptor-like tyrosine kinase | 0.0268243 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0267978 |
| SLMAP | sarcolemma associated protein | 0.0264563 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0263837 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0262458 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0262225 |
| RPL13A | ribosomal protein L13a | 0.0260623 |
| COPA | coatomer protein complex, subunit alpha | 0.0259101 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258972 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.025375 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0253209 |
| ARRDC3 | arrestin domain containing 3 | 0.0252819 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261967 |
| NDRG1 | N-myc downstream regulated 1 | -0.156974 |
| MT2A | metallothionein 2A | -0.11914 |
| FN1 | fibronectin 1 | -0.105783 |
| VIM | vimentin | -0.0845385 |
| CD44 | CD44 molecule (Indian blood group) | -0.0771514 |
| FTL | ferritin, light polypeptide | -0.0608905 |
| LOX | lysyl oxidase | -0.0554124 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0540697 |
| TMSB10 | thymosin beta 10 | -0.0536454 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0531095 |
| COL1A1 | collagen, type I, alpha 1 | -0.0496963 |
| EGR1 | early growth response 1 | -0.049382 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0475432 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0467799 |
| CDH13 | cadherin 13 | -0.0384377 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0383499 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0372822 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.037187 |
| IER3 | immediate early response 3 | -0.0363558 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0354552 |
| TAPBP | TAP binding protein (tapasin) | -0.033829 |
| MTSS1 | metastasis suppressor 1 | -0.0316484 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0314231 |
| POTEF | POTE ankyrin domain family, member F | -0.0307899 |
| TPM4 | tropomyosin 4 | -0.0303328 |
| RPS2 | ribosomal protein S2 | -0.0302374 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0301188 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0300136 |
| GNAS | GNAS complex locus | -0.0284079 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0282736 |
| NRP1 | neuropilin 1 | -0.0277738 |
| VCL | vinculin | -0.0274855 |
| OSMR | oncostatin M receptor | -0.0268456 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0266942 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0264982 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0261176 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0260281 |
| ACTG1 | actin gamma 1 | -0.0259729 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0259634 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0255947 |
| RPL28 | ribosomal protein L28 | -0.0246773 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0244871 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0239192 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.023636 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0234956 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0232186 |
| RUNX1 | runt-related transcription factor 1 | -0.0231023 |
| VEGFA | vascular endothelial growth factor A | -0.0228522 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0224376 |
| COL1A2 | collagen, type I, alpha 2 | -0.0221747 |
| COL5A1 | collagen, type V, alpha 1 | -0.0219461 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0217963 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0215791 |
| CLMP | CXADR-like membrane protein | -0.0211892 |
| HMGA2 | high mobility group AT-hook 2 | -0.0211815 |
| WASF2 | WAS protein family, member 2 | -0.020661 |
| GLIS3 | GLIS family zinc finger 3 | -0.0205932 |
| FBN1 | fibrillin 1 | -0.0204998 |
| EHD2 | EH-domain containing 2 | -0.0204779 |
| STC1 | stanniocalcin 1 | -0.0202756 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.020062 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0198316 |
| INHBA | inhibin, beta A | -0.0196195 |
| SHISA5 | shisa family member 5 | -0.0195589 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0195374 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0194513 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0194324 |
| MT1X | metallothionein 1X | -0.0192193 |
| PRMT2 | protein arginine methyltransferase 2 | -0.019184 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0191203 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0189751 |
| IL6 | interleukin 6 | -0.0186422 |
| HLA-A | major histocompatibility complex, class I, A | -0.0183555 |
| ATXN1 | ataxin 1 | -0.0182108 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0181695 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.018118 |
| RPS25 | ribosomal protein S25 | -0.0175697 |
| NAV1 | neuron navigator 1 | -0.0174871 |
| RNF220 | ring finger protein 220 | -0.0170973 |
| VCAN | versican | -0.0169889 |
| RPL36A | ribosomal protein L36a | -0.0169062 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0167433 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0166943 |
| INTS6 | integrator complex subunit 6 | -0.0164669 |
| PXDN | peroxidasin | -0.016379 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0163143 |
| S100A10 | S100 calcium binding protein A10 | -0.016212 |
| TENM3 | teneurin transmembrane protein 3 | -0.0161002 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0160008 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0159205 |
| ASPH | aspartate beta-hydroxylase | -0.0158151 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0153817 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0153814 |
| CLIC4 | chloride intracellular channel 4 | -0.0152559 |
| EGFR | epidermal growth factor receptor | -0.0150269 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.014889 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0148868 |
| CNTN5 | contactin 5 | -0.0147965 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0147944 |
