| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rifaximin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | 0.115309 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0804014 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0767734 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0725479 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0655357 |
| NPSR1 | neuropeptide S receptor 1 | 0.0569479 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0566215 |
| ITGA6 | integrin, alpha 6 | 0.0548652 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0548243 |
| FAT1 | FAT atypical cadherin 1 | 0.0502888 |
| CD46 | CD46 molecule, complement regulatory protein | 0.044995 |
| VEGFA | vascular endothelial growth factor A | 0.0420968 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0394102 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0380511 |
| PCBP2 | poly(rC) binding protein 2 | 0.0362288 |
| RPL7 | ribosomal protein L7 | 0.035749 |
| EHBP1 | EH domain binding protein 1 | 0.0344761 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0319204 |
| SETD5 | SET domain containing 5 | 0.030324 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0302196 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.030105 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.030029 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0290725 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0290051 |
| ANXA1 | annexin A1 | 0.0287748 |
| ANXA3 | annexin A3 | 0.0281039 |
| PGK1 | phosphoglycerate kinase 1 | 0.0269307 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.026317 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0262019 |
| MED13 | mediator complex subunit 13 | 0.0255301 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0251745 |
| ARF4 | ADP-ribosylation factor 4 | 0.024349 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0238317 |
| TPM4 | tropomyosin 4 | 0.0237652 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0236107 |
| FLNB | filamin B, beta | 0.0233287 |
| HDAC9 | histone deacetylase 9 | 0.0230924 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0227219 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0226231 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0225262 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223515 |
| HYOU1 | hypoxia up-regulated 1 | 0.0221627 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0221435 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0218227 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0218169 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0217076 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0215812 |
| AUTS2 | autism susceptibility candidate 2 | 0.0215639 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0215307 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0215282 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0212601 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0211258 |
| AFDN | afadin, adherens junction formation factor | 0.0209956 |
| CCNY | cyclin Y | 0.0209875 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0209422 |
| YAP1 | Yes-associated protein 1 | 0.0208813 |
| INTS6 | integrator complex subunit 6 | 0.0207012 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0204945 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0204852 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0204507 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0203201 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0202428 |
| SLK | STE20-like kinase | 0.0200834 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0200281 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0199069 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.019621 |
| FRMD5 | FERM domain containing 5 | 0.0196121 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.019597 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0194457 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0193673 |
| CCNL1 | cyclin L1 | 0.0192258 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0192002 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0187755 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0186343 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.018593 |
| DIAPH2 | diaphanous-related formin 2 | 0.0185707 |
| DENND1A | DENN/MADD domain containing 1A | 0.018485 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0184765 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0183422 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0180482 |
| FOSL1 | FOS-like antigen 1 | 0.0177413 |
| KLHL29 | kelch-like family member 29 | 0.0176553 |
| ASPH | aspartate beta-hydroxylase | 0.0175712 |
| CDK19 | cyclin-dependent kinase 19 | 0.0174897 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0174504 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.017391 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.017109 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0170835 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0170038 |
| RUNX1 | runt-related transcription factor 1 | 0.0169684 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0168844 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.016404 |
| RPS18 | ribosomal protein S18 | 0.0163902 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0162137 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0160741 |
| GOLGB1 | golgin B1 | 0.0160462 |
| RSF1 | remodeling and spacing factor 1 | 0.0159715 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0158927 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.015881 |
| FLNA | filamin A, alpha | 0.0157829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.364895 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149077 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.139343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.135566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.112317 |
| TMSB10 | thymosin beta 10 | -0.109293 |
| AGR2 | anterior gradient 2 | -0.108691 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0916351 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0897748 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0863462 |
| H1-0 | H1.0 linker histone | -0.0796626 |
| GNAS | GNAS complex locus | -0.074798 |
| PTMA | prothymosin, alpha | -0.0584139 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0576105 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0575508 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0566599 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0553841 |
| ACTN4 | actinin, alpha 4 | -0.0543949 |
| KRT8 | keratin 8, type II | -0.052935 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0495879 |
| RAB1A | RAB1A, member RAS oncogene family | -0.048016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.047821 |
| RPS27A | ribosomal protein S27a | -0.0457892 |
| RPS6 | ribosomal protein S6 | -0.0455752 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0448184 |
| ARF1 | ADP-ribosylation factor 1 | -0.0447382 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0436286 |
| HLA-C | major histocompatibility complex, class I, C | -0.0434769 |
| RPS24 | ribosomal protein S24 | -0.0393787 |
| RRBP1 | ribosome binding protein 1 | -0.0392391 |
| RPLP1 | ribosomal protein, large, P1 | -0.0391071 |
| RPS2 | ribosomal protein S2 | -0.0383264 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0380971 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0380875 |
| WDR45B | WD repeat domain 45B | -0.0378491 |
| TMC5 | transmembrane channel-like 5 | -0.0372719 |
| AHNAK | AHNAK nucleoprotein | -0.0362479 |
| HLA-E | major histocompatibility complex, class I, E | -0.0360315 |
| RPS3 | ribosomal protein S3 | -0.0359967 |
| RPL34 | ribosomal protein L34 | -0.0359382 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0352191 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0348953 |
| AHR | aryl hydrocarbon receptor | -0.0346634 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0346267 |
| EPCAM | epithelial cell adhesion molecule | -0.034583 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0342258 |
| S100A6 | S100 calcium binding protein A6 | -0.0335085 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0332629 |
| S100A10 | S100 calcium binding protein A10 | -0.0332497 |
| RPS25 | ribosomal protein S25 | -0.0322337 |
| PRSS3 | protease, serine, 3 | -0.0320744 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0320128 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0314698 |
| HMGB1 | high mobility group box 1 | -0.0314664 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0312764 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0308314 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0307395 |
| CANX | calnexin | -0.0302708 |
| LMO7 | LIM domain 7 | -0.0302456 |
| NDRG1 | N-myc downstream regulated 1 | -0.0300773 |
| GPX2 | glutathione peroxidase 2 | -0.0292681 |
| ATM | ATM serine/threonine kinase | -0.0290273 |
| HM13 | histocompatibility (minor) 13 | -0.0289494 |
| CD2AP | CD2-associated protein | -0.0288162 |
| ACTG1 | actin gamma 1 | -0.0283218 |
| SSR1 | signal sequence receptor, alpha | -0.0281373 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0278483 |
| RPL23 | ribosomal protein L23 | -0.0277886 |
| ABHD17C | abhydrolase domain containing 17C | -0.027717 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0274464 |
| GOLGA4 | golgin A4 | -0.0273576 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0267894 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267559 |
| TMEM123 | transmembrane protein 123 | -0.0267493 |
| RPS19 | ribosomal protein S19 | -0.0264878 |
| ATF5 | activating transcription factor 5 | -0.026434 |
| RPS8 | ribosomal protein S8 | -0.0262617 |
| RPL4 | ribosomal protein L4 | -0.026259 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0262295 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0258038 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0257319 |
| FTL | ferritin, light polypeptide | -0.0257242 |
| UBB | ubiquitin B | -0.0252273 |
| RPL32 | ribosomal protein L32 | -0.0251988 |
| OSBP | oxysterol binding protein | -0.0251842 |
| RACK1 | receptor for activated C kinase 1 | -0.0251757 |
| TUBB4B | tubulin, beta 4B class IVb | -0.024925 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0245534 |
| IER3 | immediate early response 3 | -0.0243429 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0242892 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0241261 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0240519 |
| S100P | S100 calcium binding protein P | -0.0239222 |
| TMEM45B | transmembrane protein 45B | -0.023922 |
| UBC | ubiquitin C | -0.0236535 |
| CALU | calumenin | -0.0234218 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0232524 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0232344 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0232021 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0230645 |
