| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rifaximin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.145624 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.100921 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0917384 |
| GOLGA4 | golgin A4 | 0.0820018 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0786262 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0696351 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0668154 |
| OGA | O-GlcNAcase | 0.0647327 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0636104 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0605174 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0603594 |
| RNF43 | ring finger protein 43 | 0.0591451 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0590167 |
| CALR | calreticulin | 0.0567288 |
| FAM13A | family with sequence similarity 13, member A | 0.0555036 |
| CANX | calnexin | 0.0542361 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.050086 |
| RPL7 | ribosomal protein L7 | 0.0488038 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0480771 |
| RBM39 | RNA binding motif protein 39 | 0.0476976 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0441131 |
| AHNAK | AHNAK nucleoprotein | 0.043606 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0406955 |
| FAT1 | FAT atypical cadherin 1 | 0.0401291 |
| EREG | epiregulin | 0.0397974 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0393133 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.038799 |
| RNF145 | ring finger protein 145 | 0.0385942 |
| MED13L | mediator complex subunit 13-like | 0.0385734 |
| KIF5B | kinesin family member 5B | 0.0377374 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0376506 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0374046 |
| NEBL | nebulette | 0.0355308 |
| PTEN | phosphatase and tensin homolog | 0.0355123 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0350143 |
| GOLGB1 | golgin B1 | 0.0348052 |
| ZNF292 | zinc finger protein 292 | 0.0344799 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0340373 |
| TXNIP | thioredoxin interacting protein | 0.0338807 |
| H1-0 | H1.0 linker histone | 0.0328935 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0321928 |
| TXNRD1 | thioredoxin reductase 1 | 0.0308852 |
| S100P | S100 calcium binding protein P | 0.0300853 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0300295 |
| GPHN | gephyrin | 0.0298211 |
| DSPP | dentin sialophosphoprotein | 0.0297148 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0295997 |
| ATXN1 | ataxin 1 | 0.0294782 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0288568 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0288023 |
| PGK1 | phosphoglycerate kinase 1 | 0.0287345 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0282393 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0280693 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0278964 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0278912 |
| PRELID2 | PRELI domain containing 2 | 0.0278376 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.027743 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0275817 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0274684 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0273686 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267813 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267579 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0266192 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0265223 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.026157 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.026105 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0258097 |
| PNN | pinin, desmosome associated protein | 0.0257043 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.025658 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025655 |
| YTHDC1 | YTH domain containing 1 | 0.0256477 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0254555 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.025448 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0254374 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0253655 |
| NUP58 | nucleoporin 58 | 0.0253261 |
| FOXJ3 | forkhead box J3 | 0.025225 |
| PCBP2 | poly(rC) binding protein 2 | 0.0251024 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0249597 |
| COG5 | component of oligomeric golgi complex 5 | 0.024896 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0248024 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0246938 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0246846 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0245599 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0245326 |
| CDK19 | cyclin-dependent kinase 19 | 0.0242657 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.024241 |
| PCM1 | pericentriolar material 1 | 0.0240003 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0239492 |
| AFDN | afadin, adherens junction formation factor | 0.0238976 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0238107 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0237496 |
| SETD5 | SET domain containing 5 | 0.0235496 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0232963 |
| CCNY | cyclin Y | 0.0232931 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.023287 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0232838 |
| ARF4 | ADP-ribosylation factor 4 | 0.0231157 |
| HDLBP | high density lipoprotein binding protein | 0.0230952 |
| TRIM2 | tripartite motif containing 2 | 0.0230163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.147375 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.146316 |
| NPSR1 | neuropeptide S receptor 1 | -0.13871 |
| TMSB10 | thymosin beta 10 | -0.137841 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0917993 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0917819 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0885442 |
| MYO1E | myosin IE | -0.0786853 |
| RPS6 | ribosomal protein S6 | -0.0760201 |
| ACTG1 | actin gamma 1 | -0.0706562 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0669933 |
| POTEF | POTE ankyrin domain family, member F | -0.0635625 |
| S100A6 | S100 calcium binding protein A6 | -0.0554393 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0525835 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0513654 |
| TFF1 | trefoil factor 1 | -0.0504638 |
| LAMA4 | laminin, alpha 4 | -0.0504615 |
| VCL | vinculin | -0.0500847 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0483551 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0477181 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0475971 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.047107 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0458134 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.045641 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0442072 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0431407 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0408985 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0403786 |
| TPM4 | tropomyosin 4 | -0.039902 |
| MUC17 | mucin 17, cell surface associated | -0.0382149 |
| KLK10 | kallikrein-related peptidase 10 | -0.0378946 |
| RPS2 | ribosomal protein S2 | -0.0377237 |
| IER3 | immediate early response 3 | -0.0369919 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.036696 |
| HMGA1 | high mobility group AT-hook 1 | -0.0364692 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0357972 |
| CALB1 | calbindin 1, 28kDa | -0.0335904 |
| MT2A | metallothionein 2A | -0.0330519 |
| GNAS | GNAS complex locus | -0.0326388 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0324754 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0318778 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0309951 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0304709 |
| TFF3 | trefoil factor 3 (intestinal) | -0.029635 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0294509 |
| TUBA1B | tubulin, alpha 1b | -0.0280449 |
| RPS25 | ribosomal protein S25 | -0.0279153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0277454 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0274083 |
| RPS8 | ribosomal protein S8 | -0.0266429 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0265583 |
| PFN1 | profilin 1 | -0.0265323 |
| RPS24 | ribosomal protein S24 | -0.026406 |
| RNF217 | ring finger protein 217 | -0.0262971 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0257794 |
| PTMA | prothymosin, alpha | -0.0255147 |
| RPL34 | ribosomal protein L34 | -0.0253865 |
| SH3D19 | SH3 domain containing 19 | -0.0249592 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0243784 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0235848 |
| CCND1 | cyclin D1 | -0.0233336 |
| RPL9 | ribosomal protein L9 | -0.0232203 |
| FRMD5 | FERM domain containing 5 | -0.0228231 |
| EGFR | epidermal growth factor receptor | -0.022471 |
| EGR1 | early growth response 1 | -0.0223851 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0217 |
| PCDH9 | protocadherin 9 | -0.0216807 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0216166 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0214383 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.020725 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0203383 |
| FBXO11 | F-box protein 11 | -0.0201891 |
| RPL36A | ribosomal protein L36a | -0.0200274 |
| RPL7A | ribosomal protein L7a | -0.0198176 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0197967 |
| RPS14 | ribosomal protein S14 | -0.0196864 |
| CSTB | cystatin B (stefin B) | -0.0192426 |
| RPS27A | ribosomal protein S27a | -0.0192397 |
| CLOCK | clock circadian regulator | -0.0190411 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0189584 |
| BMP4 | bone morphogenetic protein 4 | -0.0187779 |
| KRT18 | keratin 18, type I | -0.0185813 |
| ABHD2 | abhydrolase domain containing 2 | -0.0185693 |
| RIN2 | Ras and Rab interactor 2 | -0.0182452 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.018204 |
| KRT19 | keratin 19, type I | -0.0181144 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.018064 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0178493 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0177965 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.017402 |
| JUN | jun proto-oncogene | -0.0171697 |
| RPLP2 | ribosomal protein, large, P2 | -0.0171279 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0171123 |
| ITGA6 | integrin, alpha 6 | -0.0170463 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.016982 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0167301 |
| DGKH | diacylglycerol kinase, eta | -0.0166124 |
| PRSS3 | protease, serine, 3 | -0.0166059 |
| HMGB1 | high mobility group box 1 | -0.0166038 |
| VCAN | versican | -0.0166004 |
