| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.189257 |
| VIM | vimentin | 0.14282 |
| TP63 | tumor protein p63 | 0.134552 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.110016 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.104982 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0979838 |
| TMSB4X | thymosin beta 4, X-linked | 0.0935046 |
| CD44 | CD44 molecule (Indian blood group) | 0.0884575 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0848543 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.083926 |
| AHNAK | AHNAK nucleoprotein | 0.0821645 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0785465 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0722764 |
| HLA-B | major histocompatibility complex, class I, B | 0.0700926 |
| EHBP1 | EH domain binding protein 1 | 0.0684488 |
| CANX | calnexin | 0.0657115 |
| PGK1 | phosphoglycerate kinase 1 | 0.0628464 |
| SQSTM1 | sequestosome 1 | 0.0583654 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0580599 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0580509 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.056706 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0564515 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0556264 |
| TNS3 | tensin 3 | 0.0549365 |
| CADM2 | cell adhesion molecule 2 | 0.0540841 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.053348 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0522256 |
| SP100 | SP100 nuclear antigen | 0.0515506 |
| MYOF | myoferlin | 0.0515122 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0513195 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0496159 |
| EFNA5 | ephrin-A5 | 0.0480819 |
| FMNL2 | formin-like 2 | 0.0474012 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0467367 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0465317 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0461039 |
| RNF213 | ring finger protein 213 | 0.0450758 |
| EPHA4 | EPH receptor A4 | 0.0448211 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0448119 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0434634 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0429439 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0422481 |
| RIGI | RNA sensor RIG-I | 0.0418699 |
| EZR | ezrin | 0.0415811 |
| OGA | O-GlcNAcase | 0.0414746 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0412042 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0409359 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0406313 |
| YEATS2 | YEATS domain containing 2 | 0.039614 |
| APP | amyloid beta (A4) precursor protein | 0.039523 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0395013 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0392298 |
| HDAC9 | histone deacetylase 9 | 0.039035 |
| RUNX1 | runt-related transcription factor 1 | 0.0385969 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0383455 |
| DPYD | dihydropyrimidine dehydrogenase | 0.03834 |
| PTMA | prothymosin, alpha | 0.0380559 |
| SLK | STE20-like kinase | 0.0374339 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0374082 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0369591 |
| PTK2 | protein tyrosine kinase 2 | 0.0367597 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0365622 |
| SET | SET nuclear proto-oncogene | 0.0364314 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0363118 |
| PDE10A | phosphodiesterase 10A | 0.0348413 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0338648 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0338149 |
| EXOC4 | exocyst complex component 4 | 0.0333916 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.033339 |
| EREG | epiregulin | 0.0332409 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0329304 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0328591 |
| SPAG9 | sperm associated antigen 9 | 0.032554 |
| ANXA2 | annexin A2 | 0.0324494 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0323767 |
| GOLGB1 | golgin B1 | 0.0321581 |
| CMIP | c-Maf inducing protein | 0.0320458 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0312698 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0306732 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0302941 |
| TRIM56 | tripartite motif containing 56 | 0.0301581 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0297042 |
| PYGL | phosphorylase, glycogen, liver | 0.0296282 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0289323 |
| B2M | beta-2-microglobulin | 0.028484 |
| DNER | delta/notch-like EGF repeat containing | 0.0283979 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0282774 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0282694 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0277572 |
| TXNIP | thioredoxin interacting protein | 0.0276473 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0276426 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0275277 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.027521 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0275057 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0271178 |
| LYST | lysosomal trafficking regulator | 0.0270542 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0269854 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.026926 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0269244 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0269038 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.352681 |
| TMSB10 | thymosin beta 10 | -0.115938 |
| POTEF | POTE ankyrin domain family, member F | -0.105293 |
| MT2A | metallothionein 2A | -0.0792947 |
| ACTG1 | actin gamma 1 | -0.0587093 |
| EGR1 | early growth response 1 | -0.0577673 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462743 |
| TXNRD1 | thioredoxin reductase 1 | -0.0427728 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0404174 |
| RPL35A | ribosomal protein L35a | -0.0403458 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0398198 |
| FTL | ferritin, light polypeptide | -0.0373977 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0364083 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0344163 |
| HMGA1 | high mobility group AT-hook 1 | -0.0315089 |
| TMEM41B | transmembrane protein 41B | -0.0268381 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0261514 |
| CENPF | centromere protein F, 350/400kDa | -0.0251093 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0250032 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0242737 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0241469 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0240639 |
| QKI | QKI, KH domain containing, RNA binding | -0.0239876 |
| PFN1 | profilin 1 | -0.0237157 |
| RPL23 | ribosomal protein L23 | -0.0236794 |
| ETNK1 | ethanolamine kinase 1 | -0.0225365 |
| RTN4 | reticulon 4 | -0.0219411 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0217182 |
| RPS19 | ribosomal protein S19 | -0.0210945 |
| ATXN2L | ataxin 2-like | -0.0207326 |
| PKM | pyruvate kinase, muscle | -0.020501 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0204836 |
| TPI1 | triosephosphate isomerase 1 | -0.0201596 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0201152 |
| TNPO1 | transportin 1 | -0.0188822 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.018625 |
| RPS2 | ribosomal protein S2 | -0.0185639 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.0184801 |
| OLA1 | Obg-like ATPase 1 | -0.018392 |
| TOP1 | topoisomerase (DNA) I | -0.0183658 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0183064 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0182959 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0182502 |
| RACK1 | receptor for activated C kinase 1 | -0.0182411 |
| RPL5 | ribosomal protein L5 | -0.0177653 |
| TAPBP | TAP binding protein (tapasin) | -0.0175409 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0173808 |
| RPS8 | ribosomal protein S8 | -0.0173532 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0172648 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0170614 |
| RPL8 | ribosomal protein L8 | -0.0170498 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0170007 |
| RPS3 | ribosomal protein S3 | -0.0168512 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0167716 |
| GNAS | GNAS complex locus | -0.0166315 |
| KIF18B | kinesin family member 18B | -0.0165849 |
| PER1 | period circadian clock 1 | -0.0165041 |
| CCNL1 | cyclin L1 | -0.0164663 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0163132 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0162871 |
| RPL13A | ribosomal protein L13a | -0.0161704 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0159477 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.015941 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0159222 |
| POM121 | POM121 transmembrane nucleoporin | -0.0158652 |
| WDR43 | WD repeat domain 43 | -0.015796 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0156526 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.0155771 |
| RPL28 | ribosomal protein L28 | -0.0154949 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0152645 |
| RRM2 | ribonucleotide reductase M2 | -0.0148068 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0147317 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0147078 |
| RPS5 | ribosomal protein S5 | -0.0145954 |
| FOSL1 | FOS-like antigen 1 | -0.0143154 |
| SESN2 | sestrin 2 | -0.0142013 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0138902 |
| ASTN2 | astrotactin 2 | -0.0138824 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.01387 |
| DIAPH3 | diaphanous-related formin 3 | -0.0138356 |
| RPS23 | ribosomal protein S23 | -0.0137862 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0136479 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0136385 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0135994 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0134547 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0133034 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0132856 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0132375 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0131202 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.013026 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0130178 |
| RNF38 | ring finger protein 38 | -0.0129402 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0129208 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.0128817 |
| RHEB | Ras homolog enriched in brain | -0.0128199 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0127538 |
| RPS15 | ribosomal protein S15 | -0.0127073 |
| UCK2 | uridine-cytidine kinase 2 | -0.0126437 |
| MTMR3 | myotubularin related protein 3 | -0.0125812 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0125712 |
