| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0709981 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0484622 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.033909 |
| NGLY1 | N-glycanase 1 | 0.0304578 |
| ASPH | aspartate beta-hydroxylase | 0.0298349 |
| RPL7 | ribosomal protein L7 | 0.0283998 |
| OGA | O-GlcNAcase | 0.0269366 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0255644 |
| LMO7 | LIM domain 7 | 0.0231767 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0225035 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0219498 |
| GOLGB1 | golgin B1 | 0.0219267 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0214293 |
| HYOU1 | hypoxia up-regulated 1 | 0.021026 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0207074 |
| FAM13A | family with sequence similarity 13, member A | 0.0205984 |
| HDLBP | high density lipoprotein binding protein | 0.0201021 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0199793 |
| DSPP | dentin sialophosphoprotein | 0.0199425 |
| AHNAK | AHNAK nucleoprotein | 0.0189712 |
| SUCO | SUN domain containing ossification factor | 0.0188041 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0177508 |
| FNIP1 | folliculin interacting protein 1 | 0.0176385 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0175998 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0163645 |
| CANX | calnexin | 0.0159148 |
| PLEC | plectin | 0.0158447 |
| YEATS2 | YEATS domain containing 2 | 0.0158263 |
| LAMB3 | laminin, beta 3 | 0.0155397 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0151816 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0147751 |
| TMEM165 | transmembrane protein 165 | 0.0147332 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0146915 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0146213 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0144703 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0144342 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0143218 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0143015 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0141361 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0140867 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0140638 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0139597 |
| ARCN1 | archain 1 | 0.0138165 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0134779 |
| RBM39 | RNA binding motif protein 39 | 0.0129706 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0128923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0127406 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0127398 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0123656 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0122817 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0120723 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0118789 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0118016 |
| SLK | STE20-like kinase | 0.0116056 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0115973 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0115725 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0112742 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0112671 |
| SEC24D | SEC24 family member D | 0.0111446 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0110496 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0108214 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.010583 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0105505 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0105175 |
| FLNB | filamin B, beta | 0.0104804 |
| UBE4B | ubiquitination factor E4B | 0.0104 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0102953 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0102152 |
| ARRDC3 | arrestin domain containing 3 | 0.0100731 |
| CASC3 | cancer susceptibility candidate 3 | 0.0100402 |
| ARF4 | ADP-ribosylation factor 4 | 0.0099219 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00990608 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.00983725 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.00978572 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | 0.00950179 |
| SFXN1 | sideroflexin 1 | 0.00944985 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00943974 |
| ANXA1 | annexin A1 | 0.0092986 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00928513 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00925752 |
| YY1AP1 | YY1 associated protein 1 | 0.00925249 |
| ATXN1 | ataxin 1 | 0.0092372 |
| ABLIM1 | actin binding LIM protein 1 | 0.0091393 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00908224 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0089763 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00886701 |
| ADAM20 | ADAM metallopeptidase domain 20 | 0.00886204 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0088181 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0086387 |
| SRP54 | signal recognition particle 54kDa | 0.00858611 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00855871 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.00851919 |
| SQSTM1 | sequestosome 1 | 0.0085024 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00846243 |
| GOLGA3 | golgin A3 | 0.00837841 |
| LYST | lysosomal trafficking regulator | 0.00835183 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.00834639 |
| MLEC | malectin | 0.00830912 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00827444 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00825593 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.51724 |
| MT2A | metallothionein 2A | -0.16183 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.139094 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.111119 |
| NDRG1 | N-myc downstream regulated 1 | -0.0739035 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0722601 |
| FTL | ferritin, light polypeptide | -0.0615072 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.058228 |
| TMSB10 | thymosin beta 10 | -0.0557306 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.053961 |
| UBC | ubiquitin C | -0.0513256 |
| RPLP1 | ribosomal protein, large, P1 | -0.0493121 |
| JMJD1C | jumonji domain containing 1C | -0.0485492 |
| MCL1 | myeloid cell leukemia 1 | -0.0474953 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0464423 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0463445 |
| PKM | pyruvate kinase, muscle | -0.0452981 |
| OSMR | oncostatin M receptor | -0.0452392 |
| ENO1 | enolase 1, (alpha) | -0.0423842 |
| RPS3 | ribosomal protein S3 | -0.041619 |
| SEC61G | Sec61 gamma subunit | -0.0414997 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0411048 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0408613 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0390872 |
| STC1 | stanniocalcin 1 | -0.0382599 |
| EGR1 | early growth response 1 | -0.0382455 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0330402 |
| RPS25 | ribosomal protein S25 | -0.0326101 |
| MT1X | metallothionein 1X | -0.0325558 |
| LDHA | lactate dehydrogenase A | -0.0310192 |
| CES1 | carboxylesterase 1 | -0.0306337 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0303395 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.030125 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0298105 |
| CST3 | cystatin C | -0.0288063 |
| LAMC2 | laminin, gamma 2 | -0.0285213 |
| RPL37A | ribosomal protein L37a | -0.0283389 |
| VMP1 | vacuole membrane protein 1 | -0.0282647 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0279295 |
| RPS27A | ribosomal protein S27a | -0.0278658 |
| CCNL1 | cyclin L1 | -0.0276838 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0272602 |
| RUNX1 | runt-related transcription factor 1 | -0.0272315 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0268502 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0263847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0263026 |
| CDCP1 | CUB domain containing protein 1 | -0.0259221 |
| TXNRD1 | thioredoxin reductase 1 | -0.025854 |
| RPS6 | ribosomal protein S6 | -0.0258111 |
| RPS23 | ribosomal protein S23 | -0.0248661 |
| RTN4 | reticulon 4 | -0.0246588 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.024596 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0243855 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0237124 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.023682 |
| AREG | amphiregulin | -0.0233934 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0231398 |
| S100A10 | S100 calcium binding protein A10 | -0.0229443 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0223797 |
| RPLP0 | ribosomal protein, large, P0 | -0.0217724 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0217562 |
| RPL19 | ribosomal protein L19 | -0.021746 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0217257 |
| RPS8 | ribosomal protein S8 | -0.0211659 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0210222 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0208921 |
| FOXP1 | forkhead box P1 | -0.0206549 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0204908 |
| S100A11 | S100 calcium binding protein A11 | -0.0203342 |
| RPL31 | ribosomal protein L31 | -0.0201033 |
| IER3 | immediate early response 3 | -0.0198971 |
| ACTG1 | actin gamma 1 | -0.0198877 |
| RPS24 | ribosomal protein S24 | -0.0198495 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0198213 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0197987 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0197845 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0196303 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0195552 |
| DTNA | dystrobrevin, alpha | -0.0192065 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0191452 |
| CPE | carboxypeptidase E | -0.0191412 |
| NABP1 | nucleic acid binding protein 1 | -0.0189519 |
| CSNK1E | casein kinase 1, epsilon | -0.0188069 |
| RPL36 | ribosomal protein L36 | -0.0185483 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0183902 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0181731 |
| RPL34 | ribosomal protein L34 | -0.0180306 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0180246 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0179446 |
| MAP7 | microtubule-associated protein 7 | -0.0178531 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0178299 |
| GRAMD1B | GRAM domain containing 1B | -0.0177954 |
| RPS2 | ribosomal protein S2 | -0.0177771 |
| RPL30 | ribosomal protein L30 | -0.0176158 |
| RPLP2 | ribosomal protein, large, P2 | -0.0172102 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0170186 |
| MYO1E | myosin IE | -0.016999 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.016991 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0169872 |
| POTEF | POTE ankyrin domain family, member F | -0.016916 |
