| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.147419 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.135527 |
| EFNA5 | ephrin-A5 | 0.111789 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0955935 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0955118 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0903277 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0902432 |
| RBM39 | RNA binding motif protein 39 | 0.0810784 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0749296 |
| SMAD3 | SMAD family member 3 | 0.071488 |
| OGA | O-GlcNAcase | 0.0708924 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.069405 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0638928 |
| PRELID2 | PRELI domain containing 2 | 0.0634257 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0632008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.060944 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0600508 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0571384 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0544559 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0519555 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0486449 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0467893 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0457905 |
| CANX | calnexin | 0.0438588 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0434713 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0423219 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0405859 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0404945 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0385353 |
| NAV2 | neuron navigator 2 | 0.0375658 |
| CD44 | CD44 molecule (Indian blood group) | 0.0372098 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0369988 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0368682 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0366777 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0362889 |
| ADD3 | adducin 3 (gamma) | 0.0360002 |
| NGLY1 | N-glycanase 1 | 0.0347098 |
| RPL7 | ribosomal protein L7 | 0.0342312 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0340335 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0338964 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0336398 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0334772 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0333663 |
| AHR | aryl hydrocarbon receptor | 0.0332569 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0329706 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0325831 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0320732 |
| RASA2 | RAS p21 protein activator 2 | 0.0320277 |
| RUNX1 | runt-related transcription factor 1 | 0.0318034 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0316 |
| LMAN1 | lectin, mannose-binding, 1 | 0.031516 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0314943 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0314265 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0310567 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0307703 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0300532 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0299247 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0295063 |
| PRKCE | protein kinase C, epsilon | 0.0293169 |
| EXOC6B | exocyst complex component 6B | 0.0292599 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0291206 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0288607 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0287762 |
| KYNU | kynureninase | 0.0282471 |
| SLFN5 | schlafen family member 5 | 0.0281423 |
| IL6ST | interleukin 6 signal transducer | 0.0281161 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0281083 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0278796 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.027792 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0277902 |
| SIK3 | SIK family kinase 3 | 0.0277594 |
| FAM20C | family with sequence similarity 20, member C | 0.0276566 |
| YEATS2 | YEATS domain containing 2 | 0.0274622 |
| PCNX1 | pecanex 1 | 0.0274545 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0273716 |
| TGM2 | transglutaminase 2 | 0.0271211 |
| YBX1 | Y box binding protein 1 | 0.0271097 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0269453 |
| COG5 | component of oligomeric golgi complex 5 | 0.0268454 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0265179 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0261087 |
| RARB | retinoic acid receptor, beta | 0.0260691 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0258766 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0258429 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0257414 |
| AHNAK | AHNAK nucleoprotein | 0.0256917 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0255614 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.025456 |
| CEP250 | centrosomal protein 250kDa | 0.0251009 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0249235 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0247365 |
| MYOF | myoferlin | 0.0243986 |
| METTL15 | methyltransferase like 15 | 0.0239537 |
| NEK7 | NIMA-related kinase 7 | 0.0239522 |
| CAB39 | calcium binding protein 39 | 0.0239183 |
| STK38L | serine/threonine kinase 38 like | 0.0238869 |
| PDE8A | phosphodiesterase 8A | 0.0236912 |
| KIAA1217 | KIAA1217 | 0.0236264 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0236235 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0235902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.181099 |
| TMSB10 | thymosin beta 10 | -0.162881 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.141346 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114803 |
| LOX | lysyl oxidase | -0.0969534 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0960168 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0940898 |
| MEF2A | myocyte enhancer factor 2A | -0.0763909 |
| FTL | ferritin, light polypeptide | -0.0745308 |
| NDRG1 | N-myc downstream regulated 1 | -0.0733721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0720056 |
| CDH13 | cadherin 13 | -0.0704546 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0686834 |
| EGR1 | early growth response 1 | -0.0660481 |
| NRG1 | neuregulin 1 | -0.0584891 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0579438 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0553172 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0552915 |
| VIM | vimentin | -0.055259 |
| MTSS1 | metastasis suppressor 1 | -0.0550554 |
| SYT1 | synaptotagmin I | -0.0529325 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0524041 |
| HMGA2 | high mobility group AT-hook 2 | -0.051942 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0519107 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0508525 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.04761 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0463041 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0456147 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0430325 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0416531 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0402965 |
| GPC6 | glypican 6 | -0.0394402 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0391232 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0390964 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0388967 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0382051 |
| RAI14 | retinoic acid induced 14 | -0.0370161 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0367342 |
| AADAC | arylacetamide deacetylase | -0.0350482 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0349221 |
| RPS6 | ribosomal protein S6 | -0.0333425 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0327783 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0321687 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0320634 |
| FBN1 | fibrillin 1 | -0.0317749 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0316382 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0312751 |
| TGFB1 | transforming growth factor, beta 1 | -0.0306511 |
| HM13 | histocompatibility (minor) 13 | -0.0306187 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0299988 |
| PTMA | prothymosin, alpha | -0.0298351 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0296277 |
| OXSR1 | oxidative stress responsive 1 | -0.0292541 |
| CDK14 | cyclin-dependent kinase 14 | -0.0290142 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0286489 |
| CUX1 | cut-like homeobox 1 | -0.0285159 |
| RPS19 | ribosomal protein S19 | -0.0284748 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0279697 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0275764 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.027501 |
| POTEF | POTE ankyrin domain family, member F | -0.027444 |
| CA12 | carbonic anhydrase XII | -0.0268107 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0266441 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0264821 |
| CCDC88A | coiled-coil domain containing 88A | -0.0264683 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0264178 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0264034 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0259557 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0257429 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0256231 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0253767 |
| DNER | delta/notch-like EGF repeat containing | -0.0248086 |
| MYADM | myeloid-associated differentiation marker | -0.0246894 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0246548 |
| STC1 | stanniocalcin 1 | -0.0245898 |
| NTN4 | netrin 4 | -0.0242118 |
| RND3 | Rho family GTPase 3 | -0.0241763 |
| S100A10 | S100 calcium binding protein A10 | -0.0239694 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0236538 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0235541 |
| S100A6 | S100 calcium binding protein A6 | -0.0235431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0234245 |
| RCOR1 | REST corepressor 1 | -0.0234228 |
| PLIN2 | perilipin 2 | -0.023404 |
| COPA | coatomer protein complex, subunit alpha | -0.0231426 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0231143 |
| CLMP | CXADR-like membrane protein | -0.0229677 |
| NRCAM | neuronal cell adhesion molecule | -0.022964 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0229616 |
| IL1B | interleukin 1, beta | -0.0227848 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0227702 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0224633 |
| RASAL2 | RAS protein activator like 2 | -0.0222481 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0222013 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.022027 |
| SEC24A | SEC24 family member A | -0.021918 |
| PRRX1 | paired related homeobox 1 | -0.0218743 |
| PRSS23 | protease, serine, 23 | -0.0212986 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0212799 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0212021 |
