| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.108923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0828783 |
| GRAMD1B | GRAM domain containing 1B | 0.0754758 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0735016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0622105 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0590323 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0571484 |
| ASPH | aspartate beta-hydroxylase | 0.0525487 |
| RPL7 | ribosomal protein L7 | 0.049356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0484603 |
| RPLP1 | ribosomal protein, large, P1 | 0.0457668 |
| WWOX | WW domain containing oxidoreductase | 0.0388963 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0386687 |
| RPL23 | ribosomal protein L23 | 0.0382099 |
| RPS12 | ribosomal protein S12 | 0.0374367 |
| RPL26 | ribosomal protein L26 | 0.0361989 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0355014 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.034118 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0324226 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0316869 |
| RPS21 | ribosomal protein S21 | 0.0308838 |
| TFG | TRK-fused gene | 0.0269175 |
| USP3 | ubiquitin specific peptidase 3 | 0.02645 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263602 |
| RTN4 | reticulon 4 | 0.0248558 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0243245 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0240347 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0237096 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0232984 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0229617 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0227379 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224815 |
| ZNF292 | zinc finger protein 292 | 0.022135 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217777 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0208127 |
| RPL11 | ribosomal protein L11 | 0.0208115 |
| JAK1 | Janus kinase 1 | 0.0208106 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.019521 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0193418 |
| YBX1 | Y box binding protein 1 | 0.0193073 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0192862 |
| FHIT | fragile histidine triad | 0.01919 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0189958 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0187578 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0185554 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.018367 |
| YBX3 | Y box binding protein 3 | 0.0183628 |
| RRM2 | ribonucleotide reductase M2 | 0.0182834 |
| RPS20 | ribosomal protein S20 | 0.0181468 |
| ANXA2 | annexin A2 | 0.0180602 |
| DEK | DEK proto-oncogene | 0.0177981 |
| CANX | calnexin | 0.0177606 |
| OLA1 | Obg-like ATPase 1 | 0.0174936 |
| MKI67 | marker of proliferation Ki-67 | 0.0174058 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0173331 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0170827 |
| FAM168A | family with sequence similarity 168, member A | 0.015999 |
| FLNA | filamin A, alpha | 0.0158783 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0156813 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0156769 |
| CALR | calreticulin | 0.0156512 |
| RAI1 | retinoic acid induced 1 | 0.0155513 |
| B2M | beta-2-microglobulin | 0.0154742 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0148432 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.014747 |
| ANXA5 | annexin A5 | 0.0147265 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0146801 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0146558 |
| UPP1 | uridine phosphorylase 1 | 0.0146 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0145756 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0144511 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0143024 |
| SEPTIN2 | septin 2 | 0.0142172 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0140795 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0138507 |
| PLEC | plectin | 0.0136641 |
| RPS7 | ribosomal protein S7 | 0.0136237 |
| PFDN2 | prefoldin subunit 2 | 0.0135631 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.01354 |
| RYBP | RING1 and YY1 binding protein | 0.0135 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.013409 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0133426 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0132577 |
| CTSL | cathepsin L | 0.0131943 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0131638 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0131631 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0131102 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0131034 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.013101 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0130771 |
| ZNF410 | zinc finger protein 410 | 0.0130432 |
| LAMB1 | laminin, beta 1 | 0.0128763 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0128135 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0127899 |
| IMMT | inner membrane protein, mitochondrial | 0.0127891 |
| RPS29 | ribosomal protein S29 | 0.0127138 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0125746 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0124617 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.0124254 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.01242 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154405 |
| IGF2 | insulin-like growth factor 2 | -0.126693 |
| TMSB10 | thymosin beta 10 | -0.102221 |
| POTEF | POTE ankyrin domain family, member F | -0.091024 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0767223 |
| ACTG1 | actin gamma 1 | -0.0702394 |
| TXNRD1 | thioredoxin reductase 1 | -0.0675935 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0647246 |
| HDAC9 | histone deacetylase 9 | -0.0576953 |
| PARD3 | par-3 family cell polarity regulator | -0.0507477 |
| VIM | vimentin | -0.0507049 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0498404 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0478656 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0466916 |
| ERBIN | erbb2 interacting protein | -0.0447118 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0441197 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0436868 |
| GLG1 | golgi glycoprotein 1 | -0.0422737 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0420657 |
| FTL | ferritin, light polypeptide | -0.0401253 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0385727 |
| FMNL2 | formin-like 2 | -0.0383361 |
| COPA | coatomer protein complex, subunit alpha | -0.0380786 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0377849 |
| CMIP | c-Maf inducing protein | -0.0373799 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0372086 |
| PFN1 | profilin 1 | -0.0369624 |
| STC1 | stanniocalcin 1 | -0.0360272 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0353209 |
| EGR1 | early growth response 1 | -0.0351213 |
| HMGA1 | high mobility group AT-hook 1 | -0.0339332 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0336976 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0332503 |
| UTRN | utrophin | -0.032875 |
| LDHA | lactate dehydrogenase A | -0.0326072 |
| GNAS | GNAS complex locus | -0.0321784 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0319068 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0311391 |
| PKM | pyruvate kinase, muscle | -0.0309161 |
| NDRG1 | N-myc downstream regulated 1 | -0.0307461 |
| RASAL2 | RAS protein activator like 2 | -0.0306177 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0304268 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.030076 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0293547 |
| INO80 | INO80 complex subunit | -0.0292678 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0292407 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0289622 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0287147 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0279881 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0275752 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0270859 |
| YY1 | YY1 transcription factor | -0.0269135 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0265838 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0261982 |
| PTK2 | protein tyrosine kinase 2 | -0.026163 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0259577 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0258125 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0253749 |
| TPD52 | tumor protein D52 | -0.0252982 |
| RHOA | ras homolog family member A | -0.0249968 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0249236 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0245649 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0245408 |
| USP36 | ubiquitin specific peptidase 36 | -0.0244341 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0243585 |
| USP34 | ubiquitin specific peptidase 34 | -0.0243399 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0241997 |
| SIK3 | SIK family kinase 3 | -0.0240485 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0235727 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0235147 |
| FLNB | filamin B, beta | -0.0234956 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0230007 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0228602 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0225677 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0225244 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0224058 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0222163 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0219773 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0218768 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0216822 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0215149 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0210236 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0205926 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0204636 |
| GON4L | gon-4-like (C. elegans) | -0.020372 |
| CUX1 | cut-like homeobox 1 | -0.0199607 |
| RBM25 | RNA binding motif protein 25 | -0.0199223 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0198899 |
| CCNL1 | cyclin L1 | -0.0198144 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0197951 |
| ACACA | acetyl-CoA carboxylase alpha | -0.019748 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0197343 |
| EGFR | epidermal growth factor receptor | -0.0197313 |
| NF1 | neurofibromin 1 | -0.0195882 |
| ZNF207 | zinc finger protein 207 | -0.0193251 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.019229 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0191387 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0191168 |
| SRP54 | signal recognition particle 54kDa | -0.0191016 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0190678 |
