| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.157238 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.117813 |
| CD44 | CD44 molecule (Indian blood group) | 0.116418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.111932 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.102473 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0879091 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0852097 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0851747 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0847802 |
| PDE10A | phosphodiesterase 10A | 0.0824007 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0806159 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0762621 |
| PGK1 | phosphoglycerate kinase 1 | 0.0761445 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0761108 |
| VCL | vinculin | 0.0728096 |
| CCDC88A | coiled-coil domain containing 88A | 0.0710123 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0708658 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0700606 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0695227 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0695156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0690223 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0670175 |
| NDRG1 | N-myc downstream regulated 1 | 0.0649991 |
| FAM13A | family with sequence similarity 13, member A | 0.0646888 |
| NLGN1 | neuroligin 1 | 0.0620531 |
| EFNA5 | ephrin-A5 | 0.0618837 |
| SBF2 | SET binding factor 2 | 0.0600063 |
| ZNF638 | zinc finger protein 638 | 0.0599083 |
| HLA-B | major histocompatibility complex, class I, B | 0.0593013 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0589371 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.058844 |
| OGA | O-GlcNAcase | 0.0584327 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.057883 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.057767 |
| HELZ | helicase with zinc finger | 0.0574958 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0571646 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0568882 |
| FLNB | filamin B, beta | 0.056543 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0563325 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0558322 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.055813 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0558088 |
| TPM4 | tropomyosin 4 | 0.0555457 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0546041 |
| EGFR | epidermal growth factor receptor | 0.0530759 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0529428 |
| CALD1 | caldesmon 1 | 0.0520652 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0519731 |
| CANX | calnexin | 0.0515606 |
| APP | amyloid beta (A4) precursor protein | 0.0511367 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0509801 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0505041 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0503956 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0491561 |
| CCNL1 | cyclin L1 | 0.0485906 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0483034 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0477978 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0469265 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.046766 |
| WDR43 | WD repeat domain 43 | 0.046683 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0460269 |
| ATXN1 | ataxin 1 | 0.0456578 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0444236 |
| TXNRD1 | thioredoxin reductase 1 | 0.0440735 |
| LAMB3 | laminin, beta 3 | 0.0435661 |
| OXR1 | oxidation resistance 1 | 0.0421042 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0419474 |
| IER3 | immediate early response 3 | 0.0417391 |
| TPR | translocated promoter region, nuclear basket protein | 0.0415639 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0406991 |
| MYO10 | myosin X | 0.0404397 |
| MORF4L2 | mortality factor 4 like 2 | 0.0400945 |
| NF1 | neurofibromin 1 | 0.0399234 |
| PCBP2 | poly(rC) binding protein 2 | 0.0392423 |
| STAG2 | stromal antigen 2 | 0.0388223 |
| RNF213 | ring finger protein 213 | 0.0387629 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0376728 |
| RPL7 | ribosomal protein L7 | 0.0375107 |
| ZNF292 | zinc finger protein 292 | 0.0372462 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0364879 |
| RAD51B | RAD51 paralog B | 0.0361441 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0359223 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0358393 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0355869 |
| SRFBP1 | serum response factor binding protein 1 | 0.0350422 |
| MYOF | myoferlin | 0.0349673 |
| BRD4 | bromodomain containing 4 | 0.0347684 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.034618 |
| PRELID2 | PRELI domain containing 2 | 0.0344606 |
| DST | dystonin | 0.0343712 |
| FMNL2 | formin-like 2 | 0.0343338 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0342627 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.033123 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0330678 |
| AHNAK | AHNAK nucleoprotein | 0.0328329 |
| SEPTIN9 | septin 9 | 0.0327289 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0322101 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0312973 |
| RREB1 | ras responsive element binding protein 1 | 0.0312657 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0312445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23318 |
| FTL | ferritin, light polypeptide | -0.129514 |
| FN1 | fibronectin 1 | -0.114385 |
| PTK2 | protein tyrosine kinase 2 | -0.114104 |
| ANXA2 | annexin A2 | -0.0871402 |
| LMO7 | LIM domain 7 | -0.0738283 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0728221 |
| TMSB10 | thymosin beta 10 | -0.0722451 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0691147 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0676917 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0673901 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0669227 |
| RPLP1 | ribosomal protein, large, P1 | -0.0661568 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0650898 |
| MYO1E | myosin IE | -0.0639185 |
| TAOK3 | TAO kinase 3 | -0.0615947 |
| SRPK2 | SRSF protein kinase 2 | -0.0608985 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0601233 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0599586 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.059607 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0587168 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0581381 |
| S100A10 | S100 calcium binding protein A10 | -0.0574105 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0568663 |
| RPL35A | ribosomal protein L35a | -0.055885 |
| KLF6 | Kruppel-like factor 6 | -0.0550911 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.054162 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0538758 |
| RPS19 | ribosomal protein S19 | -0.053064 |
| CERS6 | ceramide synthase 6 | -0.0528434 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0523341 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.050033 |
| LOC112694756 | uncharaterized LOC112694756 | -0.049138 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0489556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.048482 |
| VMP1 | vacuole membrane protein 1 | -0.0484289 |
| SVIL | supervillin | -0.0482131 |
| ARF1 | ADP-ribosylation factor 1 | -0.0478547 |
| SETD5 | SET domain containing 5 | -0.0478143 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0472958 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0464666 |
| KRT17 | keratin 17, type I | -0.0461639 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0456639 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0455941 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0454505 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0449952 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0449637 |
| RPS8 | ribosomal protein S8 | -0.0446167 |
| MT2A | metallothionein 2A | -0.0441659 |
| USP53 | ubiquitin specific peptidase 53 | -0.0440316 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0434635 |
| S100A6 | S100 calcium binding protein A6 | -0.0433996 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0433106 |
| SMAD3 | SMAD family member 3 | -0.043291 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0429697 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0428398 |
| JUN | jun proto-oncogene | -0.0426213 |
| EZR | ezrin | -0.0425434 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0422148 |
| RNF149 | ring finger protein 149 | -0.0421803 |
| TMSB4X | thymosin beta 4, X-linked | -0.0420621 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0417217 |
| ANXA1 | annexin A1 | -0.0411911 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0408996 |
| RPL26 | ribosomal protein L26 | -0.0403314 |
| UBC | ubiquitin C | -0.0400276 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0392354 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0391698 |
| VIM | vimentin | -0.0391138 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0390184 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0389055 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0389003 |
| FNDC3A | fibronectin type III domain containing 3A | -0.038862 |
| RPS27A | ribosomal protein S27a | -0.038765 |
| PKM | pyruvate kinase, muscle | -0.0384374 |
| FUS | FUS RNA binding protein | -0.0383407 |
| RPS4X | ribosomal protein S4, X-linked | -0.0375343 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0374616 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0372805 |
| RBM39 | RNA binding motif protein 39 | -0.0370716 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0370091 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.036612 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0364585 |
| RPS24 | ribosomal protein S24 | -0.0362929 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0358273 |
| SMAD2 | SMAD family member 2 | -0.0356618 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0354057 |
| NPTN | neuroplastin | -0.0353414 |
| NKTR | natural killer cell triggering receptor | -0.0350708 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0349963 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0348487 |
| INTS6 | integrator complex subunit 6 | -0.034266 |
| RPL12 | ribosomal protein L12 | -0.0338849 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0336697 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0333298 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0329161 |
| PRKCA | protein kinase C, alpha | -0.032749 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0326549 |
| MCL1 | myeloid cell leukemia 1 | -0.0325789 |
| TXNIP | thioredoxin interacting protein | -0.0325719 |
