| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.152018 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.100738 |
| ASPH | aspartate beta-hydroxylase | 0.100493 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0948352 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0898767 |
| FN1 | fibronectin 1 | 0.084902 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0748163 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0704552 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0697696 |
| RBM39 | RNA binding motif protein 39 | 0.0666192 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0659241 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0657587 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.065235 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0645889 |
| RPL7 | ribosomal protein L7 | 0.063478 |
| TMSB4X | thymosin beta 4, X-linked | 0.0634056 |
| CANX | calnexin | 0.0600688 |
| LMO7 | LIM domain 7 | 0.058966 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0587931 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.058248 |
| GOLGA4 | golgin A4 | 0.0578504 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0563424 |
| AHNAK | AHNAK nucleoprotein | 0.0561391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0548971 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0547064 |
| TPM4 | tropomyosin 4 | 0.0529031 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0506704 |
| HMGB2 | high mobility group box 2 | 0.0505351 |
| OGA | O-GlcNAcase | 0.0495777 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.049337 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0465801 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0449202 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0448699 |
| SQSTM1 | sequestosome 1 | 0.0437758 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0432313 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0428117 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0421874 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0410331 |
| NAV2 | neuron navigator 2 | 0.0398165 |
| DSPP | dentin sialophosphoprotein | 0.0395923 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0394359 |
| CTSB | cathepsin B | 0.038763 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0383282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0382418 |
| CEP350 | centrosomal protein 350kDa | 0.0380428 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0372861 |
| EZR | ezrin | 0.0372571 |
| ANXA2 | annexin A2 | 0.0369958 |
| NEK7 | NIMA-related kinase 7 | 0.036684 |
| SPAG9 | sperm associated antigen 9 | 0.0363334 |
| SET | SET nuclear proto-oncogene | 0.0355804 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0354868 |
| FNIP1 | folliculin interacting protein 1 | 0.0354373 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.035307 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0351114 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0350258 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.034961 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0344969 |
| S100A6 | S100 calcium binding protein A6 | 0.0341964 |
| ERBIN | erbb2 interacting protein | 0.0341249 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0336196 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0330999 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0330469 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0329353 |
| RPLP0 | ribosomal protein, large, P0 | 0.0328259 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0324933 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0324737 |
| LDHA | lactate dehydrogenase A | 0.0324669 |
| MYO6 | myosin VI | 0.0323112 |
| TXNRD1 | thioredoxin reductase 1 | 0.0321118 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0319888 |
| RBM25 | RNA binding motif protein 25 | 0.0319847 |
| PLEC | plectin | 0.0318107 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0316095 |
| EPCAM | epithelial cell adhesion molecule | 0.0314697 |
| APP | amyloid beta (A4) precursor protein | 0.0313249 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0313153 |
| PEG10 | paternally expressed 10 | 0.0310677 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0309497 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0308616 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0308102 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0307342 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0306288 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0306155 |
| CD47 | CD47 molecule | 0.0305389 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0302046 |
| SLMAP | sarcolemma associated protein | 0.0301738 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0301355 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0301062 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0298945 |
| FLNB | filamin B, beta | 0.0296446 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0295252 |
| SMAD3 | SMAD family member 3 | 0.0294864 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.029416 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0293102 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0293026 |
| CCNY | cyclin Y | 0.0292787 |
| TMF1 | TATA element modulatory factor 1 | 0.0289263 |
| PTK2 | protein tyrosine kinase 2 | 0.0286896 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0286061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.162818 |
| FTL | ferritin, light polypeptide | -0.154163 |
| TMSB10 | thymosin beta 10 | -0.0935959 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0793856 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0653584 |
| NDRG1 | N-myc downstream regulated 1 | -0.0580511 |
| ACTG1 | actin gamma 1 | -0.0403848 |
| HMGA1 | high mobility group AT-hook 1 | -0.0385296 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0356915 |
| MT2A | metallothionein 2A | -0.0332053 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0303611 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0300759 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0274428 |
| G0S2 | G0/G1 switch 2 | -0.0269644 |
| RPL32 | ribosomal protein L32 | -0.0252031 |
| PKM | pyruvate kinase, muscle | -0.0251439 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0227004 |
| GNAS | GNAS complex locus | -0.0223992 |
| RPS19 | ribosomal protein S19 | -0.0212647 |
| MAP1B | microtubule-associated protein 1B | -0.0199166 |
| CTSD | cathepsin D | -0.0189739 |
| CCNL1 | cyclin L1 | -0.0189052 |
| MUC1 | mucin 1, cell surface associated | -0.0185342 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0185118 |
| RPS2 | ribosomal protein S2 | -0.0182714 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0173667 |
| HSPB1 | heat shock 27kDa protein 1 | -0.01718 |
| S100A10 | S100 calcium binding protein A10 | -0.0170571 |
| RPL28 | ribosomal protein L28 | -0.0169141 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0168603 |
| IER3 | immediate early response 3 | -0.0165444 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0164928 |
| RPLP2 | ribosomal protein, large, P2 | -0.0164867 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0164571 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0158055 |
| EGR1 | early growth response 1 | -0.0155354 |
| RPL36 | ribosomal protein L36 | -0.0154577 |
| RPS27 | ribosomal protein S27 | -0.0153053 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.014557 |
| S100A11 | S100 calcium binding protein A11 | -0.0144244 |
| AZIN1 | antizyme inhibitor 1 | -0.0141627 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0140855 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.0140016 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0139265 |
| RIOK3 | RIO kinase 3 | -0.0135632 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0134654 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0133412 |
| RYBP | RING1 and YY1 binding protein | -0.0133141 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.013306 |
| RPS23 | ribosomal protein S23 | -0.0132949 |
| PFN1 | profilin 1 | -0.0127426 |
| CLDN4 | claudin 4 | -0.0127193 |
| NRP1 | neuropilin 1 | -0.0126802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0125097 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0125091 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0124568 |
| CSTB | cystatin B (stefin B) | -0.0122919 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0122867 |
| RPS10 | ribosomal protein S10 | -0.0121462 |
| AREG | amphiregulin | -0.0118406 |
| RCC1 | regulator of chromosome condensation 1 | -0.0117885 |
| RPS3 | ribosomal protein S3 | -0.0115602 |
| MPZL1 | myelin protein zero-like 1 | -0.0112171 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0110293 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0110017 |
| LDHB | lactate dehydrogenase B | -0.010898 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.0108579 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.010791 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0107556 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0107519 |
| RPL35A | ribosomal protein L35a | -0.010741 |
| RPL31 | ribosomal protein L31 | -0.0105707 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0105682 |
| RPS15 | ribosomal protein S15 | -0.0105675 |
| RPS13 | ribosomal protein S13 | -0.0105176 |
| TXNIP | thioredoxin interacting protein | -0.0104908 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0102235 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0102191 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0101508 |
| RPL19 | ribosomal protein L19 | -0.0100917 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0100492 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00997287 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00995003 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.00985981 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.00983906 |
| SELENOK | selenoprotein K | -0.00983751 |
| CDK1 | cyclin-dependent kinase 1 | -0.00982189 |
| RPS25 | ribosomal protein S25 | -0.00981756 |
| MYADM | myeloid-associated differentiation marker | -0.00980007 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | -0.00968398 |
| GLRX | glutaredoxin (thioltransferase) | -0.0094018 |
| FAM162A | family with sequence similarity 162, member A | -0.00938132 |
| ANKRD37 | ankyrin repeat domain 37 | -0.00936142 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00933872 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00933367 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00929584 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.00927811 |
| ARF1 | ADP-ribosylation factor 1 | -0.00925896 |
| CST3 | cystatin C | -0.00923014 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00922352 |
