| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.188435 |
| COL11A1 | collagen, type XI, alpha 1 | 0.164057 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.138272 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123422 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.114964 |
| THBS1 | thrombospondin 1 | 0.10124 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.100169 |
| COL5A2 | collagen, type V, alpha 2 | 0.0811173 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0790958 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0763601 |
| RAI1 | retinoic acid induced 1 | 0.0720154 |
| VIM | vimentin | 0.0665286 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0650937 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0645841 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0604083 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0600829 |
| EMP1 | epithelial membrane protein 1 | 0.0584107 |
| MEIS2 | Meis homeobox 2 | 0.0582157 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0577517 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0573318 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.054003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0530955 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0510364 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0502117 |
| CANX | calnexin | 0.0476122 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0458949 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.045626 |
| TMSB4X | thymosin beta 4, X-linked | 0.0452475 |
| LRRC4C | leucine rich repeat containing 4C | 0.0448432 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0446359 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0444504 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.044326 |
| ZNF608 | zinc finger protein 608 | 0.0438765 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0430861 |
| CFL2 | cofilin 2 (muscle) | 0.0427969 |
| CALR | calreticulin | 0.0427374 |
| XPO1 | exportin 1 | 0.0424408 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0415699 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0415193 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0405543 |
| AHNAK | AHNAK nucleoprotein | 0.0404127 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0398824 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0396879 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0395336 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0390675 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0390093 |
| FBXO11 | F-box protein 11 | 0.0388632 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0382691 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0380228 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0377167 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0376616 |
| TENM3 | teneurin transmembrane protein 3 | 0.036873 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0364844 |
| SRP54 | signal recognition particle 54kDa | 0.0360288 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0359101 |
| TAOK1 | TAO kinase 1 | 0.035525 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0353139 |
| COL3A1 | collagen, type III, alpha 1 | 0.0352128 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0351848 |
| PCBP2 | poly(rC) binding protein 2 | 0.0349783 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0348894 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.03458 |
| MKI67 | marker of proliferation Ki-67 | 0.03435 |
| SNX6 | sorting nexin 6 | 0.0339248 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0337874 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0335542 |
| MATR3 | matrin 3 | 0.0335487 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0334676 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0333656 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331887 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0331708 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0329357 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0318719 |
| UPP1 | uridine phosphorylase 1 | 0.0314609 |
| ECT2 | epithelial cell transforming 2 | 0.0311913 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0309347 |
| CLTC | clathrin, heavy chain (Hc) | 0.0309079 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0308281 |
| FOXP2 | forkhead box P2 | 0.0307901 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0306402 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0306018 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0302088 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0299643 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0299434 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0297494 |
| EAPP | E2F-associated phosphoprotein | 0.0296553 |
| IPO7 | importin 7 | 0.0296097 |
| THOC2 | THO complex 2 | 0.0296089 |
| MYO10 | myosin X | 0.0293657 |
| GSK3B | glycogen synthase kinase 3 beta | 0.029274 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0290189 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0289783 |
| VIRMA | vir like m6A methyltransferase associated | 0.0288987 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0287513 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0279781 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0278765 |
| PTK2 | protein tyrosine kinase 2 | 0.0278751 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0277924 |
| WDR70 | WD repeat domain 70 | 0.027746 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0273275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.107825 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0674524 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0633762 |
| RPS19 | ribosomal protein S19 | -0.054949 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0493027 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0480169 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0475666 |
| RPS16 | ribosomal protein S16 | -0.042442 |
| PRTG | protogenin | -0.0388579 |
| FGF13 | fibroblast growth factor 13 | -0.0359621 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0356763 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347424 |
| RPL35A | ribosomal protein L35a | -0.0338433 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.03355 |
| FTL | ferritin, light polypeptide | -0.0335407 |
| GNAS | GNAS complex locus | -0.0332879 |
| RPL12 | ribosomal protein L12 | -0.0322976 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0319619 |
| RPL9 | ribosomal protein L9 | -0.0313663 |
| POTEF | POTE ankyrin domain family, member F | -0.0310208 |
| RPS3 | ribosomal protein S3 | -0.0301451 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.030099 |
| RPL5 | ribosomal protein L5 | -0.0289983 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0287806 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0285954 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.027639 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0275833 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0275219 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0274304 |
| NRXN1 | neurexin 1 | -0.0267715 |
| RPLP2 | ribosomal protein, large, P2 | -0.0267454 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0266905 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0265353 |
| PFN1 | profilin 1 | -0.026148 |
| RASAL2 | RAS protein activator like 2 | -0.0260427 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0258115 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0257703 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0254516 |
| RPS13 | ribosomal protein S13 | -0.0253939 |
| B2M | beta-2-microglobulin | -0.0249157 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0246193 |
| PARD3 | par-3 family cell polarity regulator | -0.0243029 |
| NTM | neurotrimin | -0.0242541 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0238665 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0237953 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0237898 |
| RPL31 | ribosomal protein L31 | -0.0236364 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0234964 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0233663 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0233192 |
| UBN2 | ubinuclein 2 | -0.023317 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0232781 |
| ZNF217 | zinc finger protein 217 | -0.0231715 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | -0.0231614 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0229801 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.022917 |
| CDK6 | cyclin-dependent kinase 6 | -0.0228498 |
| RPL36 | ribosomal protein L36 | -0.0228419 |
| MAST2 | microtubule associated serine/threonine kinase 2 | -0.0226489 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0225355 |
| RPL13A | ribosomal protein L13a | -0.0224676 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0224532 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0221946 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0219858 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.0219847 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0218477 |
| EPHA5 | EPH receptor A5 | -0.0217207 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0216032 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0215335 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0214498 |
| PDS5B | PDS5 cohesin associated factor B | -0.0212545 |
| RAB30 | RAB30, member RAS oncogene family | -0.0211151 |
| RPS2 | ribosomal protein S2 | -0.020663 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0205004 |
| POGZ | pogo transposable element with ZNF domain | -0.0204142 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0203682 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0202747 |
| DENND4A | DENN/MADD domain containing 4A | -0.0202192 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0201218 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0201135 |
| RPL11 | ribosomal protein L11 | -0.0200948 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0200116 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0198712 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0198598 |
| ASPH | aspartate beta-hydroxylase | -0.0198156 |
| WDR26 | WD repeat domain 26 | -0.0197653 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0192526 |
| S100A9 | S100 calcium binding protein A9 | -0.0191983 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0191165 |
| TBCA | tubulin folding cofactor A | -0.0190599 |
| MYADM | myeloid-associated differentiation marker | -0.0190265 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0188794 |
| TAPBP | TAP binding protein (tapasin) | -0.0188356 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0188031 |
| PFDN1 | prefoldin subunit 1 | -0.0187464 |
| PALLD | palladin, cytoskeletal associated protein | -0.0186153 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0185713 |
| VEGFA | vascular endothelial growth factor A | -0.0185434 |
| KIF2A | kinesin heavy chain member 2A | -0.0182805 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0182252 |
