| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rifaximin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.101631 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0976648 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0829887 |
| ZNF292 | zinc finger protein 292 | 0.0804325 |
| TXNRD1 | thioredoxin reductase 1 | 0.0799456 |
| RBM39 | RNA binding motif protein 39 | 0.077575 |
| FLNB | filamin B, beta | 0.0757579 |
| GOLGA4 | golgin A4 | 0.0705896 |
| TMSB4X | thymosin beta 4, X-linked | 0.0681608 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0672383 |
| RTN4 | reticulon 4 | 0.0651767 |
| EZR | ezrin | 0.0646633 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0603802 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0591623 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0590169 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0567658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0566055 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0552794 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0531176 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.051789 |
| PGK1 | phosphoglycerate kinase 1 | 0.0497188 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0496187 |
| NBAS | neuroblastoma amplified sequence | 0.0490158 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0474974 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0464066 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0460234 |
| NUP58 | nucleoporin 58 | 0.0454435 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0440912 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0439239 |
| COG5 | component of oligomeric golgi complex 5 | 0.0438393 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0431397 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0427845 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0426617 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0414336 |
| TMEM41B | transmembrane protein 41B | 0.0408752 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0405546 |
| TXNIP | thioredoxin interacting protein | 0.0393198 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0390788 |
| RNF145 | ring finger protein 145 | 0.0387329 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0384988 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0383338 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0378723 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0371912 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0370151 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0365917 |
| LDHA | lactate dehydrogenase A | 0.0365357 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0364376 |
| TFG | TRK-fused gene | 0.0364141 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0360833 |
| S100A6 | S100 calcium binding protein A6 | 0.0360467 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0360043 |
| NCKAP1 | NCK-associated protein 1 | 0.0355302 |
| OGA | O-GlcNAcase | 0.0354881 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0350204 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0348265 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0348086 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034771 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0347026 |
| MATR3 | matrin 3 | 0.0342864 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0342245 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0340908 |
| HDLBP | high density lipoprotein binding protein | 0.0340719 |
| SLMAP | sarcolemma associated protein | 0.0339571 |
| CALU | calumenin | 0.0337885 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0335878 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.033559 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331765 |
| QKI | QKI, KH domain containing, RNA binding | 0.0331527 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0329634 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0324682 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0324329 |
| EVI5 | ecotropic viral integration site 5 | 0.0322085 |
| CASC3 | cancer susceptibility candidate 3 | 0.0320699 |
| JMJD1C | jumonji domain containing 1C | 0.0319351 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0318616 |
| PTK2 | protein tyrosine kinase 2 | 0.0317068 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0310611 |
| NF1 | neurofibromin 1 | 0.0310418 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0309866 |
| RBM25 | RNA binding motif protein 25 | 0.0308159 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0306329 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.030363 |
| ANK2 | ankyrin 2, neuronal | 0.0300569 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0299526 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0298852 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0297524 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.029526 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.029092 |
| RHOA | ras homolog family member A | 0.0286333 |
| CDC73 | cell division cycle 73 | 0.0282215 |
| AHNAK | AHNAK nucleoprotein | 0.0280746 |
| CCNL1 | cyclin L1 | 0.0279774 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0278846 |
| WDR43 | WD repeat domain 43 | 0.0276915 |
| USP3 | ubiquitin specific peptidase 3 | 0.0276779 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0276587 |
| ECT2 | epithelial cell transforming 2 | 0.0274667 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0272093 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0269955 |
| TNPO1 | transportin 1 | 0.0267641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.132532 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.113769 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.106266 |
| BMP10 | bone morphogenetic protein 10 | -0.0904896 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0882741 |
| FOXP1 | forkhead box P1 | -0.0730641 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.057813 |
| PTMA | prothymosin, alpha | -0.0437553 |
| GLI3 | GLI family zinc finger 3 | -0.0417065 |
| RPL31 | ribosomal protein L31 | -0.0398301 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0387638 |
| RPS8 | ribosomal protein S8 | -0.0350255 |
| PDE7B | phosphodiesterase 7B | -0.0325544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0321444 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.030572 |
| INTS6 | integrator complex subunit 6 | -0.0302179 |
| DIAPH3 | diaphanous-related formin 3 | -0.0294776 |
| BMP2K | BMP2 inducible kinase | -0.0293082 |
| RPL35A | ribosomal protein L35a | -0.0292726 |
| RPL34 | ribosomal protein L34 | -0.0292477 |
| MYO5C | myosin VC | -0.0288342 |
| MKI67 | marker of proliferation Ki-67 | -0.0285229 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0280183 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0268834 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0267494 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0262821 |
| EGFR | epidermal growth factor receptor | -0.0258454 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025834 |
| RPL36 | ribosomal protein L36 | -0.0255642 |
| CCND1 | cyclin D1 | -0.0252072 |
| RPS6 | ribosomal protein S6 | -0.0252031 |
| FER1L6 | fer-1-like family member 6 | -0.0244928 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0244255 |
| SMC4 | structural maintenance of chromosomes 4 | -0.02442 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0237007 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0231513 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.022461 |
| CUX1 | cut-like homeobox 1 | -0.0224455 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0221776 |
| AEBP2 | AE binding protein 2 | -0.0216244 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0214866 |
| RPL9 | ribosomal protein L9 | -0.0213884 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.021304 |
| RPL19 | ribosomal protein L19 | -0.0209611 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0208836 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0208161 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0207524 |
| NAV2 | neuron navigator 2 | -0.0204966 |
| RPS19 | ribosomal protein S19 | -0.0203945 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0201241 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0199684 |
| RPLP2 | ribosomal protein, large, P2 | -0.0197095 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0193972 |
| ITGA10 | integrin, alpha 10 | -0.0193071 |
| ACTG1 | actin gamma 1 | -0.0187201 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0180879 |
| COMMD10 | COMM domain containing 10 | -0.0179028 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0177108 |
| PKP4 | plakophilin 4 | -0.0174267 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0174221 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0173367 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0172196 |
| GSE1 | Gse1 coiled-coil protein | -0.0172137 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0170846 |
| TBCA | tubulin folding cofactor A | -0.0167607 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0166155 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0165915 |
| TRIOBP | TRIO and F-actin binding protein | -0.0165313 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0165201 |
| BCOR | BCL6 corepressor | -0.0164731 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0163821 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0162299 |
| ONECUT2 | one cut homeobox 2 | -0.0160957 |
| PRELID2 | PRELI domain containing 2 | -0.0157003 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0151125 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0148862 |
| EMP3 | epithelial membrane protein 3 | -0.0147242 |
| TUBA1B | tubulin, alpha 1b | -0.0145464 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.014419 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0144099 |
| CCDC138 | coiled-coil domain containing 138 | -0.0143864 |
| ZNF438 | zinc finger protein 438 | -0.0141291 |
| PRSS23 | protease, serine, 23 | -0.0141169 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0141085 |
| APLF | aprataxin and PNKP like factor | -0.0139859 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0139226 |
| S100A4 | S100 calcium binding protein A4 | -0.0138961 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0137829 |
| RPL12 | ribosomal protein L12 | -0.0137192 |
| RPLP1 | ribosomal protein, large, P1 | -0.0136683 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0134876 |
| RPL5 | ribosomal protein L5 | -0.0134858 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.013348 |
| RPS2 | ribosomal protein S2 | -0.0131413 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0131294 |
| RRM2 | ribonucleotide reductase M2 | -0.013031 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0129631 |
| ACOT12 | acyl-CoA thioesterase 12 | -0.0129181 |
| IRS1 | insulin receptor substrate 1 | -0.012794 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0127925 |
