| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.211467 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.209836 |
| PGK1 | phosphoglycerate kinase 1 | 0.113957 |
| OGA | O-GlcNAcase | 0.0873396 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0835199 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.081436 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0805431 |
| PDE10A | phosphodiesterase 10A | 0.0803067 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0800453 |
| RPL7 | ribosomal protein L7 | 0.0783919 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0748478 |
| NAV2 | neuron navigator 2 | 0.0737974 |
| AHNAK | AHNAK nucleoprotein | 0.0714385 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0692389 |
| ANXA2 | annexin A2 | 0.0688189 |
| CANX | calnexin | 0.0662163 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0657671 |
| RBM39 | RNA binding motif protein 39 | 0.0654924 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0592383 |
| SPAG9 | sperm associated antigen 9 | 0.0581316 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0568245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542172 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0541228 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0523701 |
| APP | amyloid beta (A4) precursor protein | 0.0512953 |
| SMAD3 | SMAD family member 3 | 0.0512825 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0497975 |
| CENPF | centromere protein F, 350/400kDa | 0.0483783 |
| RPL26 | ribosomal protein L26 | 0.0481848 |
| TMSB4X | thymosin beta 4, X-linked | 0.0476587 |
| CEP250 | centrosomal protein 250kDa | 0.0473896 |
| AFDN | afadin, adherens junction formation factor | 0.0462525 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0452541 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0444417 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420678 |
| PHF3 | PHD finger protein 3 | 0.0417778 |
| FLNA | filamin A, alpha | 0.0415744 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0409442 |
| PRELID2 | PRELI domain containing 2 | 0.04058 |
| THBS1 | thrombospondin 1 | 0.0404743 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0400503 |
| ZNF292 | zinc finger protein 292 | 0.0400479 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0400326 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0394587 |
| CALR | calreticulin | 0.039279 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.039217 |
| MKI67 | marker of proliferation Ki-67 | 0.0388476 |
| SFTPA2 | surfactant protein A2 | 0.0385668 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0375395 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0373262 |
| SRGN | serglycin | 0.0371787 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0371727 |
| FN1 | fibronectin 1 | 0.0371468 |
| SERINC1 | serine incorporator 1 | 0.0368834 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0368393 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0361174 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.035645 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0355968 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0347843 |
| GOLGA4 | golgin A4 | 0.0345888 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0339545 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0338467 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0337896 |
| MX1 | MX dynamin-like GTPase 1 | 0.0334699 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0333453 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0327714 |
| STAG2 | stromal antigen 2 | 0.0327235 |
| ANLN | anillin, actin binding protein | 0.0325041 |
| ARF4 | ADP-ribosylation factor 4 | 0.0318143 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.031695 |
| YBX1 | Y box binding protein 1 | 0.0311327 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.031078 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0307808 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0306217 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0306033 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0303412 |
| FNIP1 | folliculin interacting protein 1 | 0.0296991 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0293724 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.028883 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0287257 |
| DST | dystonin | 0.0282332 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0281567 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0281499 |
| RLF | rearranged L-myc fusion | 0.0279564 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0279519 |
| TMF1 | TATA element modulatory factor 1 | 0.0279171 |
| FAM20C | family with sequence similarity 20, member C | 0.0276917 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0275817 |
| TPX2 | TPX2, microtubule-associated | 0.0274855 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0271912 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0269056 |
| RTN4 | reticulon 4 | 0.0268602 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0266942 |
| ATP13A3 | ATPase type 13A3 | 0.0265932 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0265561 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0265344 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0264724 |
| SQSTM1 | sequestosome 1 | 0.0263225 |
| MORF4L2 | mortality factor 4 like 2 | 0.0261961 |
| JAK1 | Janus kinase 1 | 0.0261691 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224412 |
| TMSB10 | thymosin beta 10 | -0.133868 |
| VIM | vimentin | -0.0888192 |
| NDRG1 | N-myc downstream regulated 1 | -0.0773007 |
| IER3 | immediate early response 3 | -0.0721411 |
| FTL | ferritin, light polypeptide | -0.0717034 |
| MT2A | metallothionein 2A | -0.0681069 |
| EGR1 | early growth response 1 | -0.0677348 |
| CD44 | CD44 molecule (Indian blood group) | -0.0659567 |
| CTSD | cathepsin D | -0.0604432 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0598907 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0592056 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0591719 |
| GLIS3 | GLIS family zinc finger 3 | -0.0542312 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0531468 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0524015 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0517279 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0505883 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0489449 |
| VCL | vinculin | -0.0485018 |
| RPS6 | ribosomal protein S6 | -0.0460707 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0452508 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0430915 |
| GPC6 | glypican 6 | -0.0422838 |
| HLA-B | major histocompatibility complex, class I, B | -0.0384843 |
| PLIN2 | perilipin 2 | -0.0369342 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.036828 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0363466 |
| EGFR | epidermal growth factor receptor | -0.0351929 |
| C3 | complement component 3 | -0.0348929 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0344473 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0342174 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0337463 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0331382 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0328836 |
| MT1X | metallothionein 1X | -0.0323278 |
| RPLP2 | ribosomal protein, large, P2 | -0.031106 |
| TAPBP | TAP binding protein (tapasin) | -0.0302969 |
| VMP1 | vacuole membrane protein 1 | -0.0301479 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0301306 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0301038 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0300814 |
| INHBA | inhibin, beta A | -0.0292345 |
| RPS23 | ribosomal protein S23 | -0.0285319 |
| RPS24 | ribosomal protein S24 | -0.0280172 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0279177 |
| RPL7A | ribosomal protein L7a | -0.0275285 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0274359 |
| RPS19 | ribosomal protein S19 | -0.027125 |
| RPS2 | ribosomal protein S2 | -0.0270569 |
| NABP1 | nucleic acid binding protein 1 | -0.0267488 |
| DIAPH2 | diaphanous-related formin 2 | -0.0267339 |
| HLA-E | major histocompatibility complex, class I, E | -0.0264001 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0262634 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258957 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0256122 |
| RPL36A | ribosomal protein L36a | -0.0254107 |
| FAM193A | family with sequence similarity 193, member A | -0.0250847 |
| BICC1 | BicC family RNA binding protein 1 | -0.024752 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0245501 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0244623 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.024425 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0242583 |
| TMEM132D | transmembrane protein 132D | -0.0242238 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0241057 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0240626 |
| RPL15 | ribosomal protein L15 | -0.023864 |
| VEGFA | vascular endothelial growth factor A | -0.0235096 |
| PFN1 | profilin 1 | -0.0234336 |
| FOXP1 | forkhead box P1 | -0.0233789 |
| HLA-A | major histocompatibility complex, class I, A | -0.0233114 |
| GNAS | GNAS complex locus | -0.0230184 |
| HMGA1 | high mobility group AT-hook 1 | -0.0229946 |
| S100A9 | S100 calcium binding protein A9 | -0.0223311 |
| RPL32 | ribosomal protein L32 | -0.0222287 |
| STC1 | stanniocalcin 1 | -0.0218732 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0218544 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0218505 |
| CLMP | CXADR-like membrane protein | -0.0217191 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0215068 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0212311 |
| ASTN2 | astrotactin 2 | -0.0211776 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0210345 |
| JMJD1C | jumonji domain containing 1C | -0.0208335 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0207713 |
| RPS3 | ribosomal protein S3 | -0.0207224 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0204487 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0200909 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.0200889 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0199564 |
| PKM | pyruvate kinase, muscle | -0.0197709 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0196344 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.019177 |
| TUT7 | terminal uridylyl transferase 7 | -0.0189597 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0188906 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0188881 |
| VDAC1 | voltage-dependent anion channel 1 | -0.018761 |
| GPATCH8 | G patch domain containing 8 | -0.0184398 |
| RPS16 | ribosomal protein S16 | -0.0183592 |
| RPL36 | ribosomal protein L36 | -0.0183337 |
