| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rifaximin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0673694 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0494537 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0485106 |
| PRELID2 | PRELI domain containing 2 | 0.0471464 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0466701 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0447535 |
| NAV2 | neuron navigator 2 | 0.0426353 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0419796 |
| ARRDC3 | arrestin domain containing 3 | 0.041965 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0410174 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0398054 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0397935 |
| HMGA2 | high mobility group AT-hook 2 | 0.0384654 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0378984 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0377742 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.037419 |
| MYO10 | myosin X | 0.0365688 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0364155 |
| UBXN4 | UBX domain protein 4 | 0.0357895 |
| ATP13A3 | ATPase type 13A3 | 0.0354542 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0352968 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0351565 |
| NRXN3 | neurexin 3 | 0.0330072 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0328861 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0323406 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0321729 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0318723 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0316196 |
| RASA3 | RAS p21 protein activator 3 | 0.0313809 |
| COL5A1 | collagen, type V, alpha 1 | 0.0312538 |
| HYOU1 | hypoxia up-regulated 1 | 0.0310091 |
| ZNF395 | zinc finger protein 395 | 0.0305633 |
| SMYD3 | SET and MYND domain containing 3 | 0.0305487 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0305058 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0301498 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0300393 |
| JMJD1C | jumonji domain containing 1C | 0.0298158 |
| COPA | coatomer protein complex, subunit alpha | 0.0297241 |
| SETD5 | SET domain containing 5 | 0.0294125 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0294081 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0290304 |
| ARF4 | ADP-ribosylation factor 4 | 0.028748 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0286421 |
| RPL26 | ribosomal protein L26 | 0.0282591 |
| SNX13 | sorting nexin 13 | 0.0282483 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0281378 |
| OSMR | oncostatin M receptor | 0.028116 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0281158 |
| NGLY1 | N-glycanase 1 | 0.0273697 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0272462 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0271266 |
| BBX | bobby sox homolog (Drosophila) | 0.0267123 |
| NBAS | neuroblastoma amplified sequence | 0.0263904 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0263209 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.026245 |
| ZNF451 | zinc finger protein 451 | 0.0261698 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0259759 |
| USO1 | USO1 vesicle transport factor | 0.0257296 |
| MEST | mesoderm specific transcript | 0.0257012 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0255029 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0253906 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0252577 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0251484 |
| CDH13 | cadherin 13 | 0.025105 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0250485 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0250449 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0249286 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0247384 |
| EFNA5 | ephrin-A5 | 0.0245986 |
| GOLGB1 | golgin B1 | 0.0245862 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0245653 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0245397 |
| SRPK2 | SRSF protein kinase 2 | 0.0243248 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243148 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0241703 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0239697 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0239287 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0237613 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0237392 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0237228 |
| JAK1 | Janus kinase 1 | 0.0237062 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0235255 |
| CBR4 | carbonyl reductase 4 | 0.0235094 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0234128 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0233876 |
| FBXW8 | F-box and WD repeat domain containing 8 | 0.0232953 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0232266 |
| SETX | senataxin | 0.0231906 |
| CACUL1 | CDK2-associated, cullin domain 1 | 0.0229717 |
| ZNF160 | zinc finger protein 160 | 0.0229641 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0229541 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0228778 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0228198 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0227109 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0225933 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0224584 |
| NPTN | neuroplastin | 0.0223852 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0223604 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0223348 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0221682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215628 |
| VIM | vimentin | -0.14572 |
| MT2A | metallothionein 2A | -0.141235 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140649 |
| FN1 | fibronectin 1 | -0.124167 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.102872 |
| HLA-B | major histocompatibility complex, class I, B | -0.102538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.095014 |
| TMSB10 | thymosin beta 10 | -0.091013 |
| LOX | lysyl oxidase | -0.0821497 |
| POTEF | POTE ankyrin domain family, member F | -0.0811319 |
| PTMA | prothymosin, alpha | -0.0756629 |
| COL1A1 | collagen, type I, alpha 1 | -0.0737244 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0716021 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0633132 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0610245 |
| HLA-A | major histocompatibility complex, class I, A | -0.0607756 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0577579 |
| SEPTIN7 | septin 7 | -0.0574543 |
| CD44 | CD44 molecule (Indian blood group) | -0.0531839 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0523555 |
| PKM | pyruvate kinase, muscle | -0.0522819 |
| LOXL2 | lysyl oxidase-like 2 | -0.0503955 |
| RHEB | Ras homolog enriched in brain | -0.0502124 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0501118 |
| UBC | ubiquitin C | -0.0491921 |
| HM13 | histocompatibility (minor) 13 | -0.0486369 |
| HDLBP | high density lipoprotein binding protein | -0.0475661 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0449951 |
| ENO1 | enolase 1, (alpha) | -0.0436844 |
| RPL28 | ribosomal protein L28 | -0.0435142 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0431496 |
| TPM4 | tropomyosin 4 | -0.0420885 |
| RPLP1 | ribosomal protein, large, P1 | -0.0417114 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0413804 |
| PRSS23 | protease, serine, 23 | -0.0408763 |
| STC1 | stanniocalcin 1 | -0.0407618 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0405096 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0403113 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0393207 |
| HLA-C | major histocompatibility complex, class I, C | -0.0392665 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0392495 |
| S100A10 | S100 calcium binding protein A10 | -0.0391088 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0380091 |
| CANX | calnexin | -0.0374272 |
| SEPTIN2 | septin 2 | -0.0370287 |
| ACTG1 | actin gamma 1 | -0.0367668 |
| NDRG1 | N-myc downstream regulated 1 | -0.0366379 |
| COL1A2 | collagen, type I, alpha 2 | -0.0364834 |
| ARF1 | ADP-ribosylation factor 1 | -0.036473 |
| FTL | ferritin, light polypeptide | -0.0356534 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0353312 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0352746 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0348066 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0343036 |
| H3-3B | H3.3 histone B | -0.0341229 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0338808 |
| RPS3 | ribosomal protein S3 | -0.0338481 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0336522 |
| CD99 | CD99 molecule | -0.0328879 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0327017 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0326284 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0322058 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318989 |
| RLF | rearranged L-myc fusion | -0.0317377 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317356 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0314877 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0314854 |
| FUS | FUS RNA binding protein | -0.0314732 |
| GLG1 | golgi glycoprotein 1 | -0.0312129 |
| B2M | beta-2-microglobulin | -0.031161 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0308354 |
| WASF2 | WAS protein family, member 2 | -0.0301931 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0301565 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0301557 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301334 |
| RAB10 | RAB10, member RAS oncogene family | -0.0301012 |
| ECE1 | endothelin converting enzyme 1 | -0.0299324 |
| GNAS | GNAS complex locus | -0.0298046 |
| THY1 | Thy-1 cell surface antigen | -0.0294065 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0293534 |
| BSG | basigin (Ok blood group) | -0.0286996 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0281659 |
| RPL34 | ribosomal protein L34 | -0.0278771 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0278651 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0270921 |
| CALD1 | caldesmon 1 | -0.0267645 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0266241 |
| SRGN | serglycin | -0.0265959 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264579 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0263169 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.026276 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0262644 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0259907 |
| S100A6 | S100 calcium binding protein A6 | -0.0259851 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0258851 |
| SDC4 | syndecan 4 | -0.0255847 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0255591 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.025401 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0248341 |
