| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rifaximin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rifaximin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.108169 |
| SMYD3 | SET and MYND domain containing 3 | 0.0730304 |
| RBM39 | RNA binding motif protein 39 | 0.0634277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0612727 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0608897 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0600575 |
| VIM | vimentin | 0.0570951 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0548383 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0535669 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0516149 |
| CEP250 | centrosomal protein 250kDa | 0.0506165 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0476901 |
| OGA | O-GlcNAcase | 0.0453394 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0443031 |
| RPLP1 | ribosomal protein, large, P1 | 0.0441257 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0436815 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0430211 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0423413 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0407667 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0406135 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0403462 |
| NAV2 | neuron navigator 2 | 0.0402712 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0396342 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0395881 |
| CCNT2 | cyclin T2 | 0.0394654 |
| SEPTIN7 | septin 7 | 0.0393214 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0390843 |
| RPS21 | ribosomal protein S21 | 0.0386066 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0381415 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0378034 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0369331 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0368736 |
| ANKRD12 | ankyrin repeat domain 12 | 0.036625 |
| GPC6 | glypican 6 | 0.0362482 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0360937 |
| SNX14 | sorting nexin 14 | 0.0359151 |
| LEPROT | leptin receptor overlapping transcript | 0.0348068 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0346223 |
| SLC35F5 | solute carrier family 35, member F5 | 0.033966 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0338263 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0337261 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0332329 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0331903 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0331318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0330689 |
| CANX | calnexin | 0.0328441 |
| RAB33B | RAB33B, member RAS oncogene family | 0.0328364 |
| UBXN4 | UBX domain protein 4 | 0.0325406 |
| USP34 | ubiquitin specific peptidase 34 | 0.0324424 |
| CEP95 | centrosomal protein 95kDa | 0.0322531 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0322103 |
| RPL35A | ribosomal protein L35a | 0.0321071 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0316884 |
| B2M | beta-2-microglobulin | 0.0313175 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0312845 |
| HELZ | helicase with zinc finger | 0.0311754 |
| MMP1 | matrix metallopeptidase 1 | 0.0311404 |
| FNIP1 | folliculin interacting protein 1 | 0.0310596 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.030723 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0306441 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0304859 |
| KIF4A | kinesin family member 4A | 0.0304683 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.030335 |
| CCDC88A | coiled-coil domain containing 88A | 0.0301547 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0299344 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0297868 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0297664 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0297285 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0296275 |
| YLPM1 | YLP motif containing 1 | 0.0295983 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0295905 |
| ITSN2 | intersectin 2 | 0.0293839 |
| XPO6 | exportin 6 | 0.0292035 |
| KIAA1958 | KIAA1958 | 0.0287641 |
| HJURP | Holliday junction recognition protein | 0.0286707 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0286272 |
| PTK2 | protein tyrosine kinase 2 | 0.0285896 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0284691 |
| FAM3C | family with sequence similarity 3, member C | 0.0280055 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.027986 |
| DNM1L | dynamin 1-like | 0.0278973 |
| YAP1 | Yes-associated protein 1 | 0.0277338 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0277227 |
| RTN4 | reticulon 4 | 0.0277073 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0276225 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.027202 |
| ATRN | attractin | 0.0271851 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0269545 |
| INSIG2 | insulin induced gene 2 | 0.0269468 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0269225 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.026802 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0265674 |
| FAM13A | family with sequence similarity 13, member A | 0.0263827 |
| FKBP8 | FK506 binding protein 8, 38kDa | 0.0263085 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.0262166 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0261968 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0261648 |
| SERINC1 | serine incorporator 1 | 0.0261035 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260544 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0258654 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199176 |
| CD44 | CD44 molecule (Indian blood group) | -0.118769 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0764028 |
| POTEF | POTE ankyrin domain family, member F | -0.0735049 |
| TMSB10 | thymosin beta 10 | -0.066407 |
| VMP1 | vacuole membrane protein 1 | -0.0648299 |
| UBC | ubiquitin C | -0.0617727 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0605179 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0594594 |
| ENO1 | enolase 1, (alpha) | -0.0583419 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0532234 |
| PKM | pyruvate kinase, muscle | -0.0509273 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0490589 |
| ATXN1 | ataxin 1 | -0.0482478 |
| GLG1 | golgi glycoprotein 1 | -0.04673 |
| IPO7 | importin 7 | -0.0437882 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0437644 |
| SPAG9 | sperm associated antigen 9 | -0.0428731 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0416261 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0414225 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0412523 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0411956 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0408617 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0402889 |
| CREBRF | CREB3 regulatory factor | -0.0395282 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0379871 |
| ABR | active BCR-related | -0.0375687 |
| EGR1 | early growth response 1 | -0.0375455 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0375226 |
| EFNA5 | ephrin-A5 | -0.0370921 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0368311 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0364203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0363804 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0359723 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0358292 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0356214 |
| MTMR3 | myotubularin related protein 3 | -0.0350258 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0347435 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0347425 |
| ATG7 | autophagy related 7 | -0.0346397 |
| PDE8A | phosphodiesterase 8A | -0.0344132 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0342126 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0333471 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0333416 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0327202 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0322224 |
| OSMR | oncostatin M receptor | -0.0320424 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0318871 |
| RAB10 | RAB10, member RAS oncogene family | -0.0318003 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0316976 |
| BPTF | bromodomain PHD finger transcription factor | -0.0315142 |
| PRPF4B | pre-mRNA processing factor 4B | -0.031142 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0311417 |
| OXSR1 | oxidative stress responsive 1 | -0.0304292 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0302672 |
| SSH1 | slingshot protein phosphatase 1 | -0.0299715 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0299063 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0297875 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.029563 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0295045 |
| AHNAK | AHNAK nucleoprotein | -0.029471 |
| FAM193A | family with sequence similarity 193, member A | -0.0293501 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0293341 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0293076 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0292459 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0290653 |
| ATXN2 | ataxin 2 | -0.0289281 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0288354 |
| CTTN | cortactin | -0.028754 |
| GNAS | GNAS complex locus | -0.0285813 |
| ETV1 | ets variant 1 | -0.0284302 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0284099 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0279633 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0278282 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0277618 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0276966 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.027671 |
| KHSRP | KH-type splicing regulatory protein | -0.0276574 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0276269 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0274708 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0274066 |
| CSNK1E | casein kinase 1, epsilon | -0.0270634 |
| SETD5 | SET domain containing 5 | -0.0267527 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0267256 |
| MYO6 | myosin VI | -0.026603 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0265514 |
| TES | testin LIM domain protein | -0.0264452 |
| RPS16 | ribosomal protein S16 | -0.0263845 |
| DIAPH3 | diaphanous-related formin 3 | -0.0263454 |
| H3-3B | H3.3 histone B | -0.0262687 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0262265 |
| RPS3 | ribosomal protein S3 | -0.0262218 |
| RACK1 | receptor for activated C kinase 1 | -0.0260917 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0260648 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0259392 |
| RPS8 | ribosomal protein S8 | -0.0259015 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0257518 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0256694 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0255651 |
| CUX1 | cut-like homeobox 1 | -0.0255255 |