| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.120752 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.106174 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0974945 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0955478 |
| RRM2 | ribonucleotide reductase M2 | 0.0890717 |
| YAP1 | Yes-associated protein 1 | 0.0848973 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0761189 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0718151 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0713347 |
| HMGA2 | high mobility group AT-hook 2 | 0.0664175 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0651461 |
| TPI1 | triosephosphate isomerase 1 | 0.0625988 |
| YBX3 | Y box binding protein 3 | 0.062474 |
| ASPH | aspartate beta-hydroxylase | 0.0598071 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.058617 |
| RPL3 | ribosomal protein L3 | 0.0583931 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0581457 |
| NONO | non-POU domain containing, octamer-binding | 0.0567366 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0564789 |
| MKI67 | marker of proliferation Ki-67 | 0.0563241 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0542963 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0524776 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.050917 |
| DST | dystonin | 0.0504592 |
| EGR1 | early growth response 1 | 0.0492526 |
| CALR | calreticulin | 0.0463696 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0433161 |
| LDHA | lactate dehydrogenase A | 0.042481 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0421164 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0419608 |
| ADIPOR2 | adiponectin receptor 2 | 0.0416571 |
| TPM3 | tropomyosin 3 | 0.040844 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.040805 |
| PDCD6 | programmed cell death 6 | 0.0403364 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0401573 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0398381 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.038943 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0387317 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383779 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0381603 |
| RPL37 | ribosomal protein L37 | 0.0375225 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0365493 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0356012 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0354169 |
| BRD2 | bromodomain containing 2 | 0.0340853 |
| INTS6 | integrator complex subunit 6 | 0.0340662 |
| SET | SET nuclear proto-oncogene | 0.0337247 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0336414 |
| CCN2 | cellular communication network factor 2 | 0.0333467 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0332437 |
| DBN1 | drebrin 1 | 0.0332379 |
| TMSB10 | thymosin beta 10 | 0.032674 |
| SMC1A | structural maintenance of chromosomes 1A | 0.032596 |
| FUS | FUS RNA binding protein | 0.0325737 |
| PRDX1 | peroxiredoxin 1 | 0.032282 |
| CEP250 | centrosomal protein 250kDa | 0.0321402 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0318874 |
| XPOT | exportin, tRNA | 0.0316296 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0312814 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0312245 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0311532 |
| CMIP | c-Maf inducing protein | 0.0308351 |
| CAVIN1 | caveolae associated protein 1 | 0.0308247 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0301596 |
| PLEC | plectin | 0.0301123 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0299651 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0297839 |
| CPNE1 | copine I | 0.0297302 |
| NLGN1 | neuroligin 1 | 0.0296654 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294772 |
| FLNA | filamin A, alpha | 0.0292364 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0292149 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0288392 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0288195 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0284697 |
| TUBA1B | tubulin, alpha 1b | 0.0282203 |
| TUBA1C | tubulin, alpha 1c | 0.0281983 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278544 |
| SETX | senataxin | 0.0274918 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0273657 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0272065 |
| HLA-B | major histocompatibility complex, class I, B | 0.0270839 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0269829 |
| EZR | ezrin | 0.0265182 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0262142 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0259025 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0256266 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0255841 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0254594 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0254471 |
| SON | SON DNA binding protein | 0.0252797 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.025227 |
| YBX1 | Y box binding protein 1 | 0.0251923 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0250969 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0250101 |
| RPL35A | ribosomal protein L35a | 0.0249002 |
| ATP11A | ATPase, class VI, type 11A | 0.0248838 |
| TPM4 | tropomyosin 4 | 0.0248543 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0242884 |
| DENND5A | DENN/MADD domain containing 5A | 0.0242145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207657 |
| MMP12 | matrix metallopeptidase 12 | -0.0720879 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0699931 |
| HMGA1 | high mobility group AT-hook 1 | -0.0605283 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0591438 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0507154 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0504119 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.049544 |
| BCHE | butyrylcholinesterase | -0.0463536 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0455347 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0454446 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0452918 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.044808 |
| CLDN1 | claudin 1 | -0.0437497 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0432837 |
| VMP1 | vacuole membrane protein 1 | -0.0428467 |
| MGAT4C | MGAT4 family, member C | -0.0416964 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0415584 |
| TMEM123 | transmembrane protein 123 | -0.0391857 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0391015 |
| VIM | vimentin | -0.0384681 |
| AREG | amphiregulin | -0.0381273 |
| NEK7 | NIMA-related kinase 7 | -0.0378884 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0370433 |
| SYT1 | synaptotagmin I | -0.0361894 |
| KLHL24 | kelch-like family member 24 | -0.0352851 |
| MAP4 | microtubule-associated protein 4 | -0.0340677 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0322207 |
| RPL8 | ribosomal protein L8 | -0.0315163 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0314337 |
| RPL32 | ribosomal protein L32 | -0.0304752 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0304461 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0304082 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0302075 |
| RASAL2 | RAS protein activator like 2 | -0.0301178 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0298254 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0294599 |
| USP34 | ubiquitin specific peptidase 34 | -0.0292182 |
| MED13L | mediator complex subunit 13-like | -0.0290738 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0284372 |
| CARD16 | caspase recruitment domain family, member 16 | -0.027984 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0279058 |
| TENM3 | teneurin transmembrane protein 3 | -0.0273075 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0271814 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0271129 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0270973 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0261263 |
| NF1 | neurofibromin 1 | -0.0261092 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0258164 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0256836 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.025639 |
| RBM25 | RNA binding motif protein 25 | -0.0254053 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0251769 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0246025 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0245616 |
| ZNF292 | zinc finger protein 292 | -0.0244975 |
| EDN1 | endothelin 1 | -0.0244865 |
| ZFR | zinc finger RNA binding protein | -0.0244178 |
| CDK6 | cyclin-dependent kinase 6 | -0.0241622 |
| TMEM131 | transmembrane protein 131 | -0.0238062 |
| CDK17 | cyclin-dependent kinase 17 | -0.0236839 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0232268 |
| THOC2 | THO complex 2 | -0.0231218 |
| EHBP1 | EH domain binding protein 1 | -0.0230572 |
| SBF2 | SET binding factor 2 | -0.0230509 |
| H1-0 | H1.0 linker histone | -0.0228882 |
| CD2AP | CD2-associated protein | -0.0227748 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0226742 |
| CPOX | coproporphyrinogen oxidase | -0.0226677 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0225445 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0225199 |
| XPO1 | exportin 1 | -0.0223677 |
| ANKRD28 | ankyrin repeat domain 28 | -0.022301 |
| PFN1 | profilin 1 | -0.0222657 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0220891 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.022076 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0220555 |
| HMGB1 | high mobility group box 1 | -0.0220502 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0219772 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0219556 |
| SETD5 | SET domain containing 5 | -0.0217374 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216861 |
| RPS15 | ribosomal protein S15 | -0.0215873 |
| RPL12 | ribosomal protein L12 | -0.0215828 |
| CCNI | cyclin I | -0.0215539 |
| THOC1 | THO complex 1 | -0.0214685 |
| ECT2 | epithelial cell transforming 2 | -0.0214569 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0214568 |
| R3HDM1 | R3H domain containing 1 | -0.0214551 |
| PARD3 | par-3 family cell polarity regulator | -0.0214027 |
| PRKCI | protein kinase C, iota | -0.0213206 |
| TFG | TRK-fused gene | -0.0211722 |
| CBX3 | chromobox homolog 3 | -0.0210979 |
| EPHA6 | EPH receptor A6 | -0.0209964 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0209792 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0209734 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0209528 |
| KLF6 | Kruppel-like factor 6 | -0.0209123 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0208954 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0207912 |
