| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.207877 |
| ASPH | aspartate beta-hydroxylase | 0.129375 |
| B2M | beta-2-microglobulin | 0.117602 |
| SMAD3 | SMAD family member 3 | 0.104709 |
| HLA-B | major histocompatibility complex, class I, B | 0.0912298 |
| TMSB10 | thymosin beta 10 | 0.0887754 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0841223 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0837619 |
| RNF213 | ring finger protein 213 | 0.0818591 |
| TXNRD1 | thioredoxin reductase 1 | 0.0792325 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0761807 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0656304 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0652672 |
| MSN | moesin | 0.0650755 |
| PLEC | plectin | 0.06354 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0609187 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0602918 |
| NRP2 | neuropilin 2 | 0.0592331 |
| CALR | calreticulin | 0.0582691 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0572173 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0569119 |
| NONO | non-POU domain containing, octamer-binding | 0.0541424 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0527192 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0518538 |
| CD44 | CD44 molecule (Indian blood group) | 0.0507781 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0507591 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0503185 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0487413 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0487041 |
| SON | SON DNA binding protein | 0.0481965 |
| MT2A | metallothionein 2A | 0.0473754 |
| APOL1 | apolipoprotein L, 1 | 0.0472894 |
| TGM2 | transglutaminase 2 | 0.0470201 |
| VEGFA | vascular endothelial growth factor A | 0.0470112 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0467549 |
| RPL3 | ribosomal protein L3 | 0.042515 |
| PAX8 | paired box 8 | 0.0421908 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0420451 |
| APP | amyloid beta (A4) precursor protein | 0.0406261 |
| HLA-C | major histocompatibility complex, class I, C | 0.0400265 |
| FTL | ferritin, light polypeptide | 0.0396169 |
| IFI44L | interferon-induced protein 44-like | 0.0394442 |
| SEPTIN9 | septin 9 | 0.0392522 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0387839 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0386379 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0380046 |
| HLA-A | major histocompatibility complex, class I, A | 0.0369765 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0366962 |
| HDAC9 | histone deacetylase 9 | 0.0355556 |
| TPM3 | tropomyosin 3 | 0.0354687 |
| FAT1 | FAT atypical cadherin 1 | 0.0352991 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0349364 |
| RRM2 | ribonucleotide reductase M2 | 0.0347079 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0341444 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0339897 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0327053 |
| NAV2 | neuron navigator 2 | 0.0326527 |
| FLNA | filamin A, alpha | 0.0326263 |
| MX1 | MX dynamin-like GTPase 1 | 0.0321862 |
| APOL2 | apolipoprotein L, 2 | 0.0319076 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0317645 |
| OSTC | oligosaccharyltransferase complex subunit (non-catalytic) | 0.0317551 |
| ACTN4 | actinin, alpha 4 | 0.0311952 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0311938 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0310871 |
| PFN1 | profilin 1 | 0.0310209 |
| RPS4X | ribosomal protein S4, X-linked | 0.0299626 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0294222 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0293998 |
| RPL35 | ribosomal protein L35 | 0.0288241 |
| ACTN1 | actinin, alpha 1 | 0.0288104 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0287257 |
| LDHA | lactate dehydrogenase A | 0.0287182 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0283196 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0277332 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0274032 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0273561 |
| SET | SET nuclear proto-oncogene | 0.0272955 |
| OPTN | optineurin | 0.0268952 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0265662 |
| ADAR | adenosine deaminase, RNA-specific | 0.0262569 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0261703 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0261337 |
| RPL37 | ribosomal protein L37 | 0.0260473 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.025868 |
| CMIP | c-Maf inducing protein | 0.0257838 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.025555 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0253819 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0253484 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0253357 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0252345 |
| SFTPA2 | surfactant protein A2 | 0.0251316 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0248521 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.024723 |
| GLIS3 | GLIS family zinc finger 3 | 0.0244085 |
| MINK1 | misshapen-like kinase 1 | 0.0243901 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0243268 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0241204 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0239372 |
| GUK1 | guanylate kinase 1 | 0.0237568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.147224 |
| VIM | vimentin | -0.144199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12263 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111331 |
| GPC6 | glypican 6 | -0.110559 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.103075 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0987205 |
| CP | ceruloplasmin (ferroxidase) | -0.0796128 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0790055 |
| RAI14 | retinoic acid induced 14 | -0.0716406 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0646109 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0638431 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0572863 |
| MTDH | metadherin | -0.0552626 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0529538 |
| CADM1 | cell adhesion molecule 1 | -0.0511206 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0509599 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0505403 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0495253 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0478296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0470829 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0469422 |
| ATP13A3 | ATPase type 13A3 | -0.0461976 |
| GOLGA4 | golgin A4 | -0.0454339 |
| SPAG9 | sperm associated antigen 9 | -0.0453673 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0449386 |
| GNAS | GNAS complex locus | -0.0444036 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0440533 |
| CDK13 | cyclin-dependent kinase 13 | -0.0420131 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0413596 |
| TMEM263 | transmembrane protein 263 | -0.0413584 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.040762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0407525 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0403608 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0401066 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0396719 |
| SRP72 | signal recognition particle 72kDa | -0.0395961 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0394042 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0388742 |
| INSIG1 | insulin induced gene 1 | -0.0386436 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0385688 |
| NOP58 | NOP58 ribonucleoprotein | -0.0383935 |
| SBF2 | SET binding factor 2 | -0.037791 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.037759 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0373208 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0371474 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0370357 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.036966 |
| COG5 | component of oligomeric golgi complex 5 | -0.0366828 |
| MAP4 | microtubule-associated protein 4 | -0.0365568 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0361604 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0360223 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0354022 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0351897 |
| RBM39 | RNA binding motif protein 39 | -0.0350833 |
| MMP7 | matrix metallopeptidase 7 | -0.0344608 |
| TPM4 | tropomyosin 4 | -0.0343207 |
| RRBP1 | ribosome binding protein 1 | -0.034098 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0340976 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.033992 |
| TRAM1 | translocation associated membrane protein 1 | -0.0339645 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0336078 |
| CANX | calnexin | -0.0333582 |
| DENND4C | DENN/MADD domain containing 4C | -0.0333011 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0332636 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0330531 |
| RND3 | Rho family GTPase 3 | -0.0329519 |
| DSTN | destrin (actin depolymerizing factor) | -0.0328885 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0325789 |
| SQLE | squalene epoxidase | -0.032528 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0324266 |
| TKT | transketolase | -0.0323388 |
| UBC | ubiquitin C | -0.0323008 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0318621 |
| CAVIN1 | caveolae associated protein 1 | -0.0315955 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.031465 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0314589 |
| STK17A | serine/threonine kinase 17a | -0.0312711 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0310864 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0309337 |
| TFG | TRK-fused gene | -0.0308399 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0308369 |
| MPZL1 | myelin protein zero-like 1 | -0.0305826 |
| FMNL2 | formin-like 2 | -0.0305362 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0301347 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0297624 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0294405 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0293906 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0292105 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0287284 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0284329 |
| SDCBP | syndecan binding protein (syntenin) | -0.0283284 |
| CEP350 | centrosomal protein 350kDa | -0.0282176 |
| TPM1 | tropomyosin 1 (alpha) | -0.0282052 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0281581 |
| YME1L1 | YME1-like 1 ATPase | -0.0281437 |
| HIP1 | huntingtin interacting protein 1 | -0.0279801 |
| DENND4A | DENN/MADD domain containing 4A | -0.0279014 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0277298 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275761 |
