| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.143014 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.117191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.109728 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0898717 |
| CADM2 | cell adhesion molecule 2 | 0.0892176 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0747696 |
| ACTG1 | actin gamma 1 | 0.0640028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0638867 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0636473 |
| HMGA2 | high mobility group AT-hook 2 | 0.0626011 |
| DBN1 | drebrin 1 | 0.0622009 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0549947 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0547529 |
| RPL3 | ribosomal protein L3 | 0.0547251 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0519716 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0519484 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0508475 |
| VIM | vimentin | 0.0452551 |
| EGR1 | early growth response 1 | 0.0433909 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0415418 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0382452 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0380598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0377696 |
| FRMD6 | FERM domain containing 6 | 0.037239 |
| SIK3 | SIK family kinase 3 | 0.0365735 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0365336 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0359606 |
| RPL35A | ribosomal protein L35a | 0.0359243 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0358569 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0351382 |
| NONO | non-POU domain containing, octamer-binding | 0.0349799 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0346111 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0340022 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0338124 |
| EGFR | epidermal growth factor receptor | 0.0334202 |
| FLNA | filamin A, alpha | 0.0334164 |
| MYOF | myoferlin | 0.0326751 |
| GPC6 | glypican 6 | 0.0318637 |
| RPL11 | ribosomal protein L11 | 0.0313407 |
| MGP | matrix Gla protein | 0.0305453 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0304708 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0304655 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0300653 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0296577 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0292932 |
| CEP250 | centrosomal protein 250kDa | 0.0289085 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0288704 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0287305 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0281571 |
| BRD2 | bromodomain containing 2 | 0.0280717 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.027817 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0270357 |
| ATP11A | ATPase, class VI, type 11A | 0.0265873 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0265259 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0263354 |
| IGF2 | insulin-like growth factor 2 | 0.0262688 |
| NAV1 | neuron navigator 1 | 0.0262133 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0261644 |
| SET | SET nuclear proto-oncogene | 0.0260711 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255448 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0254159 |
| ZNF516 | zinc finger protein 516 | 0.0250107 |
| PDE10A | phosphodiesterase 10A | 0.0249391 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0247635 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0245176 |
| RPL13A | ribosomal protein L13a | 0.0243959 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0243492 |
| AOPEP | aminopeptidase O (putative) | 0.0242231 |
| TSC22D1 | TSC22 domain family, member 1 | 0.023908 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0237614 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0235728 |
| FLNB | filamin B, beta | 0.0231264 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0229329 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0225877 |
| LOXL2 | lysyl oxidase-like 2 | 0.0224925 |
| RPS4X | ribosomal protein S4, X-linked | 0.0224287 |
| CTBP2 | C-terminal binding protein 2 | 0.022227 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0219814 |
| MAP1B | microtubule-associated protein 1B | 0.0218698 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0218575 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0216167 |
| ZFHX3 | zinc finger homeobox 3 | 0.0215707 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0215261 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0212843 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0208063 |
| JUN | jun proto-oncogene | 0.0206262 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0205785 |
| RPL37 | ribosomal protein L37 | 0.0205448 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0205327 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | 0.0203874 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0203778 |
| EXOC4 | exocyst complex component 4 | 0.0203484 |
| TMSB10 | thymosin beta 10 | 0.0202634 |
| RPL35 | ribosomal protein L35 | 0.0201628 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0200789 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0200535 |
| GUK1 | guanylate kinase 1 | 0.0200351 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0198502 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0197864 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.019767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195426 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0923873 |
| ZNF292 | zinc finger protein 292 | -0.0787861 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0747062 |
| MED13L | mediator complex subunit 13-like | -0.0728286 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0710028 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0651909 |
| UBC | ubiquitin C | -0.0608021 |
| MEST | mesoderm specific transcript | -0.0550165 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0547711 |
| SBF2 | SET binding factor 2 | -0.0544607 |
| QKI | QKI, KH domain containing, RNA binding | -0.0486967 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.047272 |
| MEOX2 | mesenchyme homeobox 2 | -0.0472622 |
| PEG10 | paternally expressed 10 | -0.0444972 |
| TNPO1 | transportin 1 | -0.0440041 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0439724 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0423003 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0421118 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0393599 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0387728 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0379228 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0370106 |
| HMGB2 | high mobility group box 2 | -0.0367145 |
| DIAPH3 | diaphanous-related formin 3 | -0.0366479 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0365802 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0358448 |
| HMGB1 | high mobility group box 1 | -0.035728 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0351438 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0349188 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0345306 |
| MKI67 | marker of proliferation Ki-67 | -0.0345298 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0344747 |
| NFIA | nuclear factor I/A | -0.0343902 |
| MATR3 | matrin 3 | -0.0341478 |
| CANX | calnexin | -0.0340266 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0339757 |
| TFG | TRK-fused gene | -0.0337103 |
| RBM39 | RNA binding motif protein 39 | -0.0336826 |
| SMAP1 | small ArfGAP 1 | -0.0335481 |
| USP3 | ubiquitin specific peptidase 3 | -0.0335176 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0330365 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0329665 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327541 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0327375 |
| RPS23 | ribosomal protein S23 | -0.0323941 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.032292 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0320811 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0317213 |
| MAP4 | microtubule-associated protein 4 | -0.0316885 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0315691 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0314997 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0311995 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0307634 |
| GOLGA4 | golgin A4 | -0.0307624 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0304426 |
| RTN4 | reticulon 4 | -0.0300193 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0299705 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0298289 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0297799 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0296338 |
| RYBP | RING1 and YY1 binding protein | -0.0295637 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0295512 |
| KLHDC10 | kelch domain containing 10 | -0.0293931 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0293247 |
| WTAP | Wilms tumor 1 associated protein | -0.0292035 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0291784 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291452 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0288105 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0287996 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0286631 |
| TMEM123 | transmembrane protein 123 | -0.0286063 |
| CCNI | cyclin I | -0.0284962 |
| DENND4C | DENN/MADD domain containing 4C | -0.0283498 |
| RPS2 | ribosomal protein S2 | -0.0283192 |
| ECT2 | epithelial cell transforming 2 | -0.0279673 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0279528 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0279432 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0275623 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274916 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0274896 |
| RPS27A | ribosomal protein S27a | -0.027434 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0272931 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0271691 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0270339 |
| CD2AP | CD2-associated protein | -0.0270071 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0269266 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.026781 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0266373 |
| RPS12 | ribosomal protein S12 | -0.0263131 |
| RBM25 | RNA binding motif protein 25 | -0.0260414 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0259901 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.025935 |
| ATP13A3 | ATPase type 13A3 | -0.0257572 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0257373 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.025629 |
| ENAH | enabled homolog (Drosophila) | -0.0255686 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.025566 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0254999 |
| RNF145 | ring finger protein 145 | -0.0252038 |
