| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.199521 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.117689 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.112266 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.104269 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0955491 |
| KLK10 | kallikrein-related peptidase 10 | 0.0906875 |
| EGFR | epidermal growth factor receptor | 0.0877959 |
| TXNRD1 | thioredoxin reductase 1 | 0.0858553 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0819529 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0790403 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0732888 |
| PMM2 | phosphomannomutase 2 | 0.0715373 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0692745 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0671812 |
| MXD1 | MAX dimerization protein 1 | 0.0609025 |
| LAMA4 | laminin, alpha 4 | 0.0605139 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0593108 |
| LMO7 | LIM domain 7 | 0.0560992 |
| FERMT1 | fermitin family member 1 | 0.0546743 |
| BMP6 | bone morphogenetic protein 6 | 0.0543776 |
| LAMC2 | laminin, gamma 2 | 0.0538578 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0528582 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0522616 |
| HMGA2 | high mobility group AT-hook 2 | 0.0504983 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0504378 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0489256 |
| TRRAP | transformation/transcription domain-associated protein | 0.0466586 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0443647 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0437843 |
| MSN | moesin | 0.0437682 |
| SLC35F3 | solute carrier family 35, member F3 | 0.043473 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0423013 |
| HDLBP | high density lipoprotein binding protein | 0.0418847 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0414711 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0414181 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0414001 |
| CLMP | CXADR-like membrane protein | 0.0412728 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407887 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0407057 |
| ACTN4 | actinin, alpha 4 | 0.0383324 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0381599 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0376061 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0368347 |
| RASAL2 | RAS protein activator like 2 | 0.0366793 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0361843 |
| TXNIP | thioredoxin interacting protein | 0.0359389 |
| RRBP1 | ribosome binding protein 1 | 0.0355282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0354341 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0354221 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0351284 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0348616 |
| AK1 | adenylate kinase 1 | 0.0344504 |
| PDLIM5 | PDZ and LIM domain 5 | 0.034192 |
| SON | SON DNA binding protein | 0.0340815 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339389 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0337134 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336955 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0327251 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0325778 |
| MMP1 | matrix metallopeptidase 1 | 0.0324072 |
| GOLGA3 | golgin A3 | 0.0321429 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0320447 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0318618 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0316792 |
| RNF213 | ring finger protein 213 | 0.0316243 |
| CALU | calumenin | 0.0314517 |
| PDCD6 | programmed cell death 6 | 0.0310126 |
| FBXO11 | F-box protein 11 | 0.0309974 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.030922 |
| PLEC | plectin | 0.0307717 |
| HDAC9 | histone deacetylase 9 | 0.0306343 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0306229 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0304934 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0301268 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0299533 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.029525 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0288292 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0285751 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0285645 |
| HM13 | histocompatibility (minor) 13 | 0.0280521 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0279788 |
| SVIL | supervillin | 0.027962 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0279257 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0277536 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0274919 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0274388 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.027416 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.02713 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0270883 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0270627 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0267857 |
| RAD51B | RAD51 paralog B | 0.0266817 |
| FLNA | filamin A, alpha | 0.0265591 |
| SP100 | SP100 nuclear antigen | 0.0263647 |
| EFNB2 | ephrin-B2 | 0.0261919 |
| TPM4 | tropomyosin 4 | 0.0260243 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0258184 |
| TGM2 | transglutaminase 2 | 0.0254998 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0253801 |
| MCL1 | myeloid cell leukemia 1 | 0.0252937 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.254584 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.155611 |
| POTEF | POTE ankyrin domain family, member F | -0.155125 |
| NDRG1 | N-myc downstream regulated 1 | -0.128271 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.126223 |
| ITGA6 | integrin, alpha 6 | -0.118981 |
| S100A10 | S100 calcium binding protein A10 | -0.106217 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.100847 |
| TSC22D2 | TSC22 domain family, member 2 | -0.094733 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0866615 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0791011 |
| PTMA | prothymosin, alpha | -0.0767475 |
| RIOK3 | RIO kinase 3 | -0.0751606 |
| VIM | vimentin | -0.0724712 |
| HMGA1 | high mobility group AT-hook 1 | -0.0715 |
| TMSB10 | thymosin beta 10 | -0.0713149 |
| MUC17 | mucin 17, cell surface associated | -0.0651438 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0628728 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0619779 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0583162 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0548475 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0540323 |
| RPS6 | ribosomal protein S6 | -0.0536939 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.053333 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0518285 |
| RTN4 | reticulon 4 | -0.05159 |
| JMJD1C | jumonji domain containing 1C | -0.0512027 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0506744 |
| UBC | ubiquitin C | -0.0479234 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0477442 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0476777 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0476313 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.045864 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0455276 |
| WASF2 | WAS protein family, member 2 | -0.045278 |
| SPAG9 | sperm associated antigen 9 | -0.0450729 |
| RPS2 | ribosomal protein S2 | -0.0442853 |
| ZNF292 | zinc finger protein 292 | -0.043861 |
| CCNL1 | cyclin L1 | -0.0438222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0437934 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0433257 |
| RPLP1 | ribosomal protein, large, P1 | -0.0429407 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0428733 |
| ANLN | anillin, actin binding protein | -0.0411469 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0411074 |
| NEK7 | NIMA-related kinase 7 | -0.0397975 |
| PCBP2 | poly(rC) binding protein 2 | -0.039757 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0390871 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0387995 |
| RPS23 | ribosomal protein S23 | -0.0386858 |
| TOP1 | topoisomerase (DNA) I | -0.0386471 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0377211 |
| RPS8 | ribosomal protein S8 | -0.0373817 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0372031 |
| RPS3 | ribosomal protein S3 | -0.0361712 |
| RPL12 | ribosomal protein L12 | -0.0357922 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0357585 |
| RPS12 | ribosomal protein S12 | -0.0356042 |
| RPL8 | ribosomal protein L8 | -0.0349953 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0346264 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0345529 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0339902 |
| DSTN | destrin (actin depolymerizing factor) | -0.0339039 |
| FOSL1 | FOS-like antigen 1 | -0.033541 |
| GOLGA4 | golgin A4 | -0.0332719 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0331689 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0330284 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0328829 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0325479 |
| PKM | pyruvate kinase, muscle | -0.0325431 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0321013 |
| SLMAP | sarcolemma associated protein | -0.0317295 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0316875 |
| NPTN | neuroplastin | -0.0315381 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0313316 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0307885 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -0.0307039 |
| CCDC88A | coiled-coil domain containing 88A | -0.0306482 |
| SBF2 | SET binding factor 2 | -0.030449 |
| CUL3 | cullin 3 | -0.0304425 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0302633 |
| SERTAD2 | SERTA domain containing 2 | -0.0298769 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0294947 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0294908 |
| RNF145 | ring finger protein 145 | -0.0293746 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0292256 |
| RPS14 | ribosomal protein S14 | -0.0290374 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0288984 |
| RPL7 | ribosomal protein L7 | -0.0286236 |
| RPL5 | ribosomal protein L5 | -0.028473 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0283163 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0283149 |
| ARRDC3 | arrestin domain containing 3 | -0.0281885 |
| RPLP2 | ribosomal protein, large, P2 | -0.0280202 |
| CD2AP | CD2-associated protein | -0.0276993 |
| RPL34 | ribosomal protein L34 | -0.0276196 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0275711 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0275056 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0273637 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0273432 |
