| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.144783 |
| TENM3 | teneurin transmembrane protein 3 | 0.135844 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.114552 |
| LOC112694756 | uncharaterized LOC112694756 | 0.109581 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0889397 |
| NONO | non-POU domain containing, octamer-binding | 0.0777892 |
| DST | dystonin | 0.0732727 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0687614 |
| RPL3 | ribosomal protein L3 | 0.067049 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0654902 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0649352 |
| ZNF608 | zinc finger protein 608 | 0.0643331 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0640521 |
| RAD51B | RAD51 paralog B | 0.0605385 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0598546 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0591155 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0582854 |
| CEP250 | centrosomal protein 250kDa | 0.0572247 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0561454 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0543688 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0540425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0536984 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0532234 |
| WLS | wntless Wnt ligand secretion mediator | 0.0509248 |
| DBN1 | drebrin 1 | 0.0502233 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0498282 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0486025 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0473087 |
| TMSB10 | thymosin beta 10 | 0.0464966 |
| RPL11 | ribosomal protein L11 | 0.0464875 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0462297 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0446149 |
| SET | SET nuclear proto-oncogene | 0.0444624 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0433116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0429639 |
| SMYD3 | SET and MYND domain containing 3 | 0.0417957 |
| ATP11A | ATPase, class VI, type 11A | 0.041595 |
| MKI67 | marker of proliferation Ki-67 | 0.0414798 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0412362 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0410171 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0404379 |
| RRM2 | ribonucleotide reductase M2 | 0.0401697 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0395714 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0382605 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.038173 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0378895 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0377159 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.037463 |
| PRELID3B | PRELI domain containing 3B | 0.0372749 |
| YBX1 | Y box binding protein 1 | 0.0371185 |
| SHROOM3 | shroom family member 3 | 0.0366391 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0364922 |
| COL5A2 | collagen, type V, alpha 2 | 0.0362438 |
| SON | SON DNA binding protein | 0.0361002 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0354827 |
| MAGEA4 | melanoma antigen family A4 | 0.0353403 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0350423 |
| LDHA | lactate dehydrogenase A | 0.0347843 |
| RPS4X | ribosomal protein S4, X-linked | 0.0344954 |
| CENPF | centromere protein F, 350/400kDa | 0.0344215 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0341979 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0341978 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0341636 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0338034 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0333781 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0332014 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0328694 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.032569 |
| PNN | pinin, desmosome associated protein | 0.0325105 |
| ACTG1 | actin gamma 1 | 0.0323674 |
| FAT1 | FAT atypical cadherin 1 | 0.0319315 |
| RIGI | RNA sensor RIG-I | 0.0315529 |
| NEBL | nebulette | 0.0313484 |
| RPL13A | ribosomal protein L13a | 0.0310931 |
| CDH18 | cadherin 18, type 2 | 0.030973 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0308844 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0302185 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0300122 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0299846 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0299822 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.029859 |
| DENND1A | DENN/MADD domain containing 1A | 0.0297259 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0294259 |
| DIDO1 | death inducer-obliterator 1 | 0.0293624 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0291719 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0290324 |
| MLIP | muscular LMNA-interacting protein | 0.0289304 |
| ATG10 | autophagy related 10 | 0.0288655 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0281775 |
| SEPTIN2 | septin 2 | 0.0274464 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0273011 |
| RPLP0 | ribosomal protein, large, P0 | 0.0270596 |
| BNC2 | basonuclin 2 | 0.0270272 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0269999 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0267456 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0267122 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0266153 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0261919 |
| RBM28 | RNA binding motif protein 28 | 0.0261053 |
| HELLS | helicase, lymphoid-specific | 0.0260271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224529 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0851129 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0821757 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0812039 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0798193 |
| UBC | ubiquitin C | -0.0743675 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0704453 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0627522 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0602511 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0580104 |
| WDR45B | WD repeat domain 45B | -0.0566012 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0544778 |
| ZNF292 | zinc finger protein 292 | -0.0525974 |
| PTMA | prothymosin, alpha | -0.0486137 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0471464 |
| RPS11 | ribosomal protein S11 | -0.0471227 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0456157 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0455065 |
| RPS27A | ribosomal protein S27a | -0.0437194 |
| RPL5 | ribosomal protein L5 | -0.0436677 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0418397 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0412672 |
| RYBP | RING1 and YY1 binding protein | -0.0408166 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0408161 |
| SEPTIN7 | septin 7 | -0.0407994 |
| JMJD1C | jumonji domain containing 1C | -0.0405582 |
| EFNA5 | ephrin-A5 | -0.0398014 |
| ATRN | attractin | -0.0387761 |
| RPS15 | ribosomal protein S15 | -0.0378158 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0375842 |
| RPL23 | ribosomal protein L23 | -0.0375021 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0363314 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0361561 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0359947 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0354455 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0352887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0351712 |
| RAB1A | RAB1A, member RAS oncogene family | -0.035077 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0344879 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0343777 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0343762 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0343301 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0341687 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0330416 |
| HMGB1 | high mobility group box 1 | -0.0329465 |
| ZNF638 | zinc finger protein 638 | -0.0327934 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0327085 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0325997 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.032503 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0321784 |
| RPS8 | ribosomal protein S8 | -0.0320494 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0319042 |
| PAPOLA | poly(A) polymerase alpha | -0.0315737 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0312634 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0310445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0310262 |
| CDC73 | cell division cycle 73 | -0.0310144 |
| NUP58 | nucleoporin 58 | -0.0309242 |
| FOXO3 | forkhead box O3 | -0.0308966 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0303221 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0302617 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0301376 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0301139 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0300928 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0300722 |
| RPS24 | ribosomal protein S24 | -0.0300721 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0299063 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0297245 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0291279 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0289604 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0288468 |
| RLF | rearranged L-myc fusion | -0.0286126 |
| MED14 | mediator complex subunit 14 | -0.0286005 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0281273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0279933 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.02797 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0277258 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0276613 |
| PARD3 | par-3 family cell polarity regulator | -0.0275791 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0273224 |
| HHIP | hedgehog interacting protein | -0.0271825 |
| RNF145 | ring finger protein 145 | -0.0270678 |
| SETD5 | SET domain containing 5 | -0.0270219 |
| RPS23 | ribosomal protein S23 | -0.0269036 |
| GPHN | gephyrin | -0.0268756 |
| QKI | QKI, KH domain containing, RNA binding | -0.0265717 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0264592 |
| PHIP | pleckstrin homology domain interacting protein | -0.0263565 |
| RPL32 | ribosomal protein L32 | -0.0258985 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0258896 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0255168 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0254195 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0254126 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0253986 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0252391 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0251633 |
| CCNI | cyclin I | -0.0250502 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0250404 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0249927 |
| NOP58 | NOP58 ribonucleoprotein | -0.0248968 |
