| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.150086 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.12873 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.116782 |
| LOC112694756 | uncharaterized LOC112694756 | 0.103923 |
| MT2A | metallothionein 2A | 0.0934514 |
| FMN1 | formin 1 | 0.0911038 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0900855 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0723262 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0704697 |
| GPC6 | glypican 6 | 0.0639852 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0638546 |
| FRMD4A | FERM domain containing 4A | 0.0627186 |
| NLGN1 | neuroligin 1 | 0.0620028 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0617276 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0592881 |
| TAGLN2 | transgelin 2 | 0.0589088 |
| ACTN1 | actinin, alpha 1 | 0.0542422 |
| DST | dystonin | 0.0534594 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0525726 |
| PRELID2 | PRELI domain containing 2 | 0.0511637 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0507138 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0497271 |
| MT1X | metallothionein 1X | 0.0487897 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0480216 |
| CD59 | CD59 molecule, complement regulatory protein | 0.044816 |
| SDC2 | syndecan 2 | 0.0443389 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0438728 |
| TNNC1 | troponin C type 1 (slow) | 0.0432882 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0427257 |
| SETBP1 | SET binding protein 1 | 0.0424924 |
| ACTG1 | actin gamma 1 | 0.0424833 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0424736 |
| ZYX | zyxin | 0.042276 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0403796 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0399245 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0395556 |
| HLA-C | major histocompatibility complex, class I, C | 0.0383623 |
| TMSB10 | thymosin beta 10 | 0.038088 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0374944 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0364286 |
| LDHA | lactate dehydrogenase A | 0.0355325 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343776 |
| CALD1 | caldesmon 1 | 0.0338433 |
| PLEC | plectin | 0.0335385 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0331092 |
| EXOC4 | exocyst complex component 4 | 0.0330095 |
| CENPF | centromere protein F, 350/400kDa | 0.0326344 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0323231 |
| VGF | VGF nerve growth factor inducible | 0.0323158 |
| RPL3 | ribosomal protein L3 | 0.0316576 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0312422 |
| MSN | moesin | 0.0312321 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0306702 |
| RAD51B | RAD51 paralog B | 0.0297308 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0283781 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028336 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0277358 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0277351 |
| PCDH7 | protocadherin 7 | 0.0276374 |
| SFTPA2 | surfactant protein A2 | 0.027458 |
| AFDN | afadin, adherens junction formation factor | 0.0267625 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0267126 |
| SON | SON DNA binding protein | 0.0262793 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0261787 |
| MACROD2 | MACRO domain containing 2 | 0.02595 |
| NRP2 | neuropilin 2 | 0.0258307 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0249263 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0248074 |
| GSN | gelsolin | 0.0243811 |
| AHR | aryl hydrocarbon receptor | 0.0240785 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 | 0.0240132 |
| RNF213 | ring finger protein 213 | 0.0238298 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0233424 |
| SVIL | supervillin | 0.0233172 |
| OXR1 | oxidation resistance 1 | 0.0232287 |
| STRIP2 | striatin interacting protein 2 | 0.0231683 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0230811 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0230591 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0226286 |
| SYNM | synemin, intermediate filament protein | 0.0225761 |
| CEP250 | centrosomal protein 250kDa | 0.0224878 |
| B2M | beta-2-microglobulin | 0.0222732 |
| APP | amyloid beta (A4) precursor protein | 0.0221695 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0219547 |
| SMYD3 | SET and MYND domain containing 3 | 0.0217429 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0217243 |
| RCAN1 | regulator of calcineurin 1 | 0.0217218 |
| NAV1 | neuron navigator 1 | 0.0216578 |
| VCL | vinculin | 0.0215742 |
| FLNA | filamin A, alpha | 0.0215317 |
| NONO | non-POU domain containing, octamer-binding | 0.0215055 |
| PDE10A | phosphodiesterase 10A | 0.0214655 |
| PRKD1 | protein kinase D1 | 0.0213707 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0211781 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0211138 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0211093 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0208446 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0203596 |
| ASPH | aspartate beta-hydroxylase | 0.0201194 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0199768 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.498095 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.151625 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.102023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0914929 |
| GDF15 | growth differentiation factor 15 | -0.0914693 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0790779 |
| NDRG1 | N-myc downstream regulated 1 | -0.0764221 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0721167 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0670369 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0659926 |
| CDC73 | cell division cycle 73 | -0.0646558 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0635244 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.062095 |
| VIM | vimentin | -0.0619011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0551634 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0519562 |
| PTMA | prothymosin, alpha | -0.0516527 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0500925 |
| IER3 | immediate early response 3 | -0.0499138 |
| ZNF292 | zinc finger protein 292 | -0.0493298 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0479904 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0465773 |
| RHEB | Ras homolog enriched in brain | -0.043494 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0432673 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.042876 |
| WDR45B | WD repeat domain 45B | -0.042714 |
| GNAS | GNAS complex locus | -0.0420721 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0412415 |
| CD109 | CD109 molecule | -0.040704 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0403057 |
| DCT | dopachrome tautomerase | -0.0400295 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0398904 |
| PTK2 | protein tyrosine kinase 2 | -0.0398547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0395144 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.039514 |
| FMNL2 | formin-like 2 | -0.0390776 |
| NPR2 | natriuretic peptide receptor 2 | -0.0387586 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0387207 |
| HELZ | helicase with zinc finger | -0.0386805 |
| TMEM123 | transmembrane protein 123 | -0.0386216 |
| COG5 | component of oligomeric golgi complex 5 | -0.0383855 |
| RLF | rearranged L-myc fusion | -0.0377236 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0373089 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0371434 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.03648 |
| NUP58 | nucleoporin 58 | -0.0360014 |
| FBXO11 | F-box protein 11 | -0.0358706 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0358509 |
| RYBP | RING1 and YY1 binding protein | -0.0358056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0357929 |
| TRIM2 | tripartite motif containing 2 | -0.0346271 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0343128 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0338686 |
| COPA | coatomer protein complex, subunit alpha | -0.0324854 |
| CUX1 | cut-like homeobox 1 | -0.0323939 |
| TPD52 | tumor protein D52 | -0.0317276 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0312323 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0310282 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0308368 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0308061 |
| PHF21A | PHD finger protein 21A | -0.030687 |
| PTCHD4 | patched domain containing 4 | -0.0306706 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0304497 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0302012 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0301686 |
| RPS8 | ribosomal protein S8 | -0.0299861 |
| RNF24 | ring finger protein 24 | -0.0297347 |
| LRRC23 | leucine rich repeat containing 23 | -0.0296091 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0293076 |
| RNF145 | ring finger protein 145 | -0.0291154 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0283158 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0282632 |
| NBAS | neuroblastoma amplified sequence | -0.0282614 |
| CERT1 | ceramide transporter 1 | -0.0281021 |
| UBC | ubiquitin C | -0.0280566 |
| MEF2A | myocyte enhancer factor 2A | -0.0280429 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0277214 |
| MRTFA | myocardin related transcription factor A | -0.0276061 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0275771 |
| SEC24A | SEC24 family member A | -0.0275272 |
| FUS | FUS RNA binding protein | -0.0274413 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0269302 |
| SETD5 | SET domain containing 5 | -0.0268519 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0264194 |
| PKM | pyruvate kinase, muscle | -0.026388 |
| GOLGA4 | golgin A4 | -0.0263052 |
| TMEM263 | transmembrane protein 263 | -0.0258502 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256857 |
| FTL | ferritin, light polypeptide | -0.0256362 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.025549 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0254364 |
| GLG1 | golgi glycoprotein 1 | -0.0253132 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0252829 |
| SBF2 | SET binding factor 2 | -0.025268 |
| HIP1 | huntingtin interacting protein 1 | -0.0245556 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0244194 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0244029 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0243213 |
| CDK14 | cyclin-dependent kinase 14 | -0.0241898 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.024061 |
