| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOL1 | apolipoprotein L, 1 | 0.269358 |
| B2M | beta-2-microglobulin | 0.136048 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.135122 |
| LOC112694756 | uncharaterized LOC112694756 | 0.101014 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0991032 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0956311 |
| APOL2 | apolipoprotein L, 2 | 0.0919742 |
| HLA-C | major histocompatibility complex, class I, C | 0.087294 |
| DST | dystonin | 0.0821464 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0723908 |
| TMSB4X | thymosin beta 4, X-linked | 0.0712395 |
| ANXA11 | annexin A11 | 0.0703868 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0696402 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0671869 |
| MUC4 | mucin 4, cell surface associated | 0.066798 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0659659 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0644227 |
| TGM2 | transglutaminase 2 | 0.0641575 |
| KRT8 | keratin 8, type II | 0.0637102 |
| BCL2L1 | BCL2-like 1 | 0.0604295 |
| APP | amyloid beta (A4) precursor protein | 0.0595568 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0595557 |
| HLA-B | major histocompatibility complex, class I, B | 0.0573383 |
| BICC1 | BicC family RNA binding protein 1 | 0.0533425 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0520823 |
| RNF213 | ring finger protein 213 | 0.0516028 |
| HLA-A | major histocompatibility complex, class I, A | 0.0511431 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0501313 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.049852 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0496428 |
| PLAU | plasminogen activator, urokinase | 0.0489475 |
| PGK1 | phosphoglycerate kinase 1 | 0.0480574 |
| CD2AP | CD2-associated protein | 0.0477248 |
| LCN2 | lipocalin 2 | 0.0472886 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.047145 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0457208 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0452264 |
| CALR | calreticulin | 0.0450411 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0444157 |
| MACC1 | metastasis associated in colon cancer 1 | 0.04248 |
| HLA-E | major histocompatibility complex, class I, E | 0.0419804 |
| NONO | non-POU domain containing, octamer-binding | 0.0405683 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0402878 |
| KRT18 | keratin 18, type I | 0.0399525 |
| FAM3C | family with sequence similarity 3, member C | 0.0388148 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.038752 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0386009 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0382695 |
| HRNR | hornerin | 0.0370952 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.037002 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0361472 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0348317 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0346543 |
| LDHA | lactate dehydrogenase A | 0.0341682 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.033731 |
| LAMB3 | laminin, beta 3 | 0.0334871 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0324989 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323615 |
| CFB | complement factor B | 0.0313837 |
| SMAD3 | SMAD family member 3 | 0.0313423 |
| CD47 | CD47 molecule | 0.0312448 |
| CEP250 | centrosomal protein 250kDa | 0.031021 |
| PLEC | plectin | 0.0305282 |
| SDC4 | syndecan 4 | 0.0304418 |
| PDZD8 | PDZ domain containing 8 | 0.0297851 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0296379 |
| OSMR | oncostatin M receptor | 0.0295509 |
| TMEM51 | transmembrane protein 51 | 0.028004 |
| JUP | junction plakoglobin | 0.0278973 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277738 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0277372 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0276812 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0276742 |
| SFTPA2 | surfactant protein A2 | 0.0276025 |
| RLIM | ring finger protein, LIM domain interacting | 0.0274868 |
| LAMC2 | laminin, gamma 2 | 0.0274548 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0274234 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.02734 |
| MX2 | MX dynamin-like GTPase 2 | 0.0269481 |
| ACTN1 | actinin, alpha 1 | 0.0268671 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.026786 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0259181 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0257972 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0257761 |
| PHF3 | PHD finger protein 3 | 0.0257222 |
| KRT19 | keratin 19, type I | 0.0257167 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0256399 |
| FMN1 | formin 1 | 0.0253865 |
| SQOR | sulfide quinone oxidoreductase | 0.0251921 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0250285 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0250049 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0249503 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0247256 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0245407 |
| NRP1 | neuropilin 1 | 0.0242707 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.024254 |
| RPL3 | ribosomal protein L3 | 0.0242249 |
| FOXP1 | forkhead box P1 | 0.0242038 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0240648 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0238337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21979 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.145301 |
| MT2A | metallothionein 2A | -0.136884 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.129472 |
| HMGA1 | high mobility group AT-hook 1 | -0.0975208 |
| DTNA | dystrobrevin, alpha | -0.0838815 |
| NDRG1 | N-myc downstream regulated 1 | -0.0775937 |
| POTEF | POTE ankyrin domain family, member F | -0.0754713 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0750923 |
| PTMA | prothymosin, alpha | -0.0673425 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0641859 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0622358 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0563659 |
| VIM | vimentin | -0.056046 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0557561 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0542382 |
| ACTG1 | actin gamma 1 | -0.0534467 |
| UBC | ubiquitin C | -0.0515185 |
| GNAS | GNAS complex locus | -0.0514299 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0481932 |
| IER3 | immediate early response 3 | -0.0467918 |
| RBM39 | RNA binding motif protein 39 | -0.0466211 |
| RCOR1 | REST corepressor 1 | -0.0465824 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0465601 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0463084 |
| MEF2A | myocyte enhancer factor 2A | -0.0445664 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0434518 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0427077 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426796 |
| S100A10 | S100 calcium binding protein A10 | -0.0420319 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0417696 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0413647 |
| SPAG9 | sperm associated antigen 9 | -0.0405549 |
| NABP1 | nucleic acid binding protein 1 | -0.0405367 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0401114 |
| RAB7A | RAB7A, member RAS oncogene family | -0.039997 |
| RPLP1 | ribosomal protein, large, P1 | -0.0399672 |
| PARD3 | par-3 family cell polarity regulator | -0.0396527 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0394771 |
| RPS6 | ribosomal protein S6 | -0.0393457 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0392223 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0381236 |
| SEC24A | SEC24 family member A | -0.0377612 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0377164 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0371271 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0368898 |
| RPS23 | ribosomal protein S23 | -0.0366271 |
| RPS8 | ribosomal protein S8 | -0.0365642 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0361807 |
| SRP54 | signal recognition particle 54kDa | -0.0355027 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0352678 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0342023 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.03359 |
| INTS6 | integrator complex subunit 6 | -0.0327099 |
| RPL5 | ribosomal protein L5 | -0.0323378 |
| RAI14 | retinoic acid induced 14 | -0.0322237 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0319552 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0317648 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0317559 |
| CCNY | cyclin Y | -0.0313129 |
| TAPBP | TAP binding protein (tapasin) | -0.0311964 |
| ZNF207 | zinc finger protein 207 | -0.0309449 |
| VMP1 | vacuole membrane protein 1 | -0.0306761 |
| HELZ | helicase with zinc finger | -0.0306069 |
| MAP1B | microtubule-associated protein 1B | -0.0301102 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0300942 |
| FAM13A | family with sequence similarity 13, member A | -0.0300744 |
| USP34 | ubiquitin specific peptidase 34 | -0.0297318 |
| PKM | pyruvate kinase, muscle | -0.029458 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0291291 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0286536 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0286421 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0283609 |
| HMGA2 | high mobility group AT-hook 2 | -0.0283568 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0283268 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0282511 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0282322 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0281124 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0278288 |
| RIOK3 | RIO kinase 3 | -0.0275679 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0272862 |
| WDR45B | WD repeat domain 45B | -0.0267842 |
| GOLGA4 | golgin A4 | -0.0267266 |
| SNX6 | sorting nexin 6 | -0.0265445 |
| RBM25 | RNA binding motif protein 25 | -0.0264918 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0264654 |
| RTN3 | reticulon 3 | -0.0264166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0263468 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0262823 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0261642 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0259583 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0256737 |
| SP100 | SP100 nuclear antigen | -0.0251676 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0251401 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0249342 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.024861 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0246655 |
| RPS29 | ribosomal protein S29 | -0.0246292 |
| RPS11 | ribosomal protein S11 | -0.0241388 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.023951 |
