| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Riluzole hydrochloride_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.220974 |
| NRG1 | neuregulin 1 | 0.141547 |
| IGF2 | insulin-like growth factor 2 | 0.136264 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.135711 |
| ANTXR1 | anthrax toxin receptor 1 | 0.118274 |
| EXT1 | exostosin glycosyltransferase 1 | 0.115027 |
| ACTG1 | actin gamma 1 | 0.112928 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.110833 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.109516 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.107723 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0987006 |
| RNF213 | ring finger protein 213 | 0.0860809 |
| LSAMP | limbic system-associated membrane protein | 0.0777488 |
| FMN1 | formin 1 | 0.0756836 |
| RPL23 | ribosomal protein L23 | 0.0704005 |
| DST | dystonin | 0.0646081 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0611221 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0593194 |
| DNM3 | dynamin 3 | 0.0590256 |
| TLE4 | transducin-like enhancer of split 4 | 0.0559418 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0554994 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0544014 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.054176 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0532193 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0531773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0524591 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0500575 |
| MAP1B | microtubule-associated protein 1B | 0.0498058 |
| DGKH | diacylglycerol kinase, eta | 0.0489393 |
| RPL35A | ribosomal protein L35a | 0.0485056 |
| TENM4 | teneurin transmembrane protein 4 | 0.0485054 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0483297 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0477327 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0473911 |
| AOPEP | aminopeptidase O (putative) | 0.0463297 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0463247 |
| SON | SON DNA binding protein | 0.0459145 |
| FAM107B | family with sequence similarity 107, member B | 0.0457173 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0456941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0456047 |
| AUTS2 | autism susceptibility candidate 2 | 0.0432997 |
| VGF | VGF nerve growth factor inducible | 0.0431286 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0427151 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0425465 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0423161 |
| FRMD4A | FERM domain containing 4A | 0.0416699 |
| MSI2 | musashi RNA-binding protein 2 | 0.04102 |
| IGF1R | insulin-like growth factor 1 receptor | 0.040567 |
| CNTN4 | contactin 4 | 0.0401231 |
| FN1 | fibronectin 1 | 0.0386988 |
| APP | amyloid beta (A4) precursor protein | 0.0379867 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0378961 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0375762 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0372065 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371629 |
| TMSB10 | thymosin beta 10 | 0.0367606 |
| PRKCA | protein kinase C, alpha | 0.0365666 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0364751 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0362397 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0360153 |
| NONO | non-POU domain containing, octamer-binding | 0.0354473 |
| KLHL13 | kelch-like family member 13 | 0.0348606 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0346436 |
| SCG2 | secretogranin II | 0.0344454 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0339562 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0338681 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0334096 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0332542 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332291 |
| RPL11 | ribosomal protein L11 | 0.0324365 |
| RET | ret proto-oncogene | 0.0323276 |
| EGR1 | early growth response 1 | 0.0322801 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0321738 |
| CADM1 | cell adhesion molecule 1 | 0.0320763 |
| CRH | corticotropin releasing hormone | 0.0319091 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0318794 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.031655 |
| SEPTIN2 | septin 2 | 0.0316073 |
| ADAR | adenosine deaminase, RNA-specific | 0.0313802 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0312169 |
| RPL7 | ribosomal protein L7 | 0.0311527 |
| H3-3B | H3.3 histone B | 0.0306424 |
| RPL37 | ribosomal protein L37 | 0.030612 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.030326 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0301641 |
| SP100 | SP100 nuclear antigen | 0.0299443 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0296658 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0295465 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0292689 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0292569 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0292396 |
| SYT1 | synaptotagmin I | 0.0290519 |
| SIK3 | SIK family kinase 3 | 0.0289346 |
| SEPTIN9 | septin 9 | 0.0288925 |
| PDE10A | phosphodiesterase 10A | 0.0288872 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0286863 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0284615 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0281219 |
| RPS19 | ribosomal protein S19 | 0.0279489 |
| ACTN1 | actinin, alpha 1 | 0.0278823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.241396 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165474 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0605027 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0435889 |
| GOLGA4 | golgin A4 | -0.0410624 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0369899 |
| VMP1 | vacuole membrane protein 1 | -0.0340823 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0340817 |
| PLAT | plasminogen activator, tissue | -0.0333982 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.032439 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.032358 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0322562 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0309426 |
| COL3A1 | collagen, type III, alpha 1 | -0.0295933 |
| ZNF292 | zinc finger protein 292 | -0.0290287 |
| GPC5 | glypican 5 | -0.0288921 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0284061 |
| MCL1 | myeloid cell leukemia 1 | -0.0276913 |
| ZNF638 | zinc finger protein 638 | -0.0269724 |
| SRP54 | signal recognition particle 54kDa | -0.0262796 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260843 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | -0.0260412 |
| TRIB2 | tribbles pseudokinase 2 | -0.0255864 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0227835 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0226051 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0225301 |
| KLHL24 | kelch-like family member 24 | -0.0223875 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0221293 |
| PAPOLA | poly(A) polymerase alpha | -0.0217163 |
| PCDH9 | protocadherin 9 | -0.021639 |
| MAP4 | microtubule-associated protein 4 | -0.021616 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0214223 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0210063 |
| MKI67 | marker of proliferation Ki-67 | -0.0210001 |
| XPO1 | exportin 1 | -0.0207861 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0206528 |
| WDR26 | WD repeat domain 26 | -0.0206119 |
| DPH6 | diphthamine biosynthesis 6 | -0.0205577 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.019589 |
| HMGA1 | high mobility group AT-hook 1 | -0.0195564 |
| CDC27 | cell division cycle 27 | -0.019279 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0192563 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.019148 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0191429 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0191122 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0188914 |
| KIF5B | kinesin family member 5B | -0.0187331 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0187317 |
| RIOK3 | RIO kinase 3 | -0.0185691 |
| WDR45B | WD repeat domain 45B | -0.018387 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0179165 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.017881 |
| HOMER1 | homer scaffolding protein 1 | -0.0178493 |
| OLA1 | Obg-like ATPase 1 | -0.0178408 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0177504 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0174944 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0174068 |
| EPHA3 | EPH receptor A3 | -0.0172939 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0172748 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0172684 |
| RBM27 | RNA binding motif protein 27 | -0.017225 |
| COG5 | component of oligomeric golgi complex 5 | -0.0172052 |
| USP8 | ubiquitin specific peptidase 8 | -0.017179 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0171746 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0171708 |
| RYBP | RING1 and YY1 binding protein | -0.0171211 |
| NOP58 | NOP58 ribonucleoprotein | -0.0169595 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.0168591 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0168244 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0168016 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0167342 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0167042 |
| MACROD2 | MACRO domain containing 2 | -0.016681 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0166807 |
| RAI14 | retinoic acid induced 14 | -0.0163191 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0162314 |
| CDK19 | cyclin-dependent kinase 19 | -0.0161236 |
| GNAS | GNAS complex locus | -0.0160932 |
| ZBTB41 | zinc finger and BTB domain containing 41 | -0.0160784 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0159622 |
| KIF21A | kinesin family member 21A | -0.0159319 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0158036 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0157966 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0155521 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0155422 |
| GOLGB1 | golgin B1 | -0.0155187 |
| PBRM1 | polybromo 1 | -0.0154599 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0154198 |
| VCL | vinculin | -0.0154124 |
| CLTC | clathrin, heavy chain (Hc) | -0.0153946 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0151493 |
| PHKB | phosphorylase kinase, beta | -0.015144 |
| CEP290 | centrosomal protein 290kDa | -0.0151192 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0150358 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0149746 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -0.0149154 |
| PKM | pyruvate kinase, muscle | -0.0148372 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0148006 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0147574 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0147263 |
