| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.192688 |
| LCN2 | lipocalin 2 | 0.135495 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.123759 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.12074 |
| SMAD3 | SMAD family member 3 | 0.110471 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.106982 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0973136 |
| B2M | beta-2-microglobulin | 0.091005 |
| HLA-B | major histocompatibility complex, class I, B | 0.0886246 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0828172 |
| EPHB2 | EPH receptor B2 | 0.0801565 |
| RUNX1 | runt-related transcription factor 1 | 0.0740368 |
| MLPH | melanophilin | 0.0694359 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0680476 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0638457 |
| APOL1 | apolipoprotein L, 1 | 0.0616658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0584373 |
| RNF213 | ring finger protein 213 | 0.0584047 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.057601 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0563627 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0550867 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0540243 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0538452 |
| ATP11A | ATPase, class VI, type 11A | 0.053339 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0527979 |
| MYO1E | myosin IE | 0.0511561 |
| KRT8 | keratin 8, type II | 0.0490305 |
| MSI2 | musashi RNA-binding protein 2 | 0.0486586 |
| HDAC4 | histone deacetylase 4 | 0.0484468 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0478093 |
| FAT1 | FAT atypical cadherin 1 | 0.0469862 |
| DST | dystonin | 0.0465942 |
| YAP1 | Yes-associated protein 1 | 0.0452642 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0452291 |
| NCOR2 | nuclear receptor corepressor 2 | 0.045182 |
| RNF43 | ring finger protein 43 | 0.0442217 |
| DUSP16 | dual specificity phosphatase 16 | 0.0439365 |
| JUN | jun proto-oncogene | 0.0432178 |
| MYO5B | myosin VB | 0.0427875 |
| NONO | non-POU domain containing, octamer-binding | 0.0425264 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0416571 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0414608 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0399527 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0399079 |
| HLA-A | major histocompatibility complex, class I, A | 0.0397268 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0395315 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.038535 |
| ABHD2 | abhydrolase domain containing 2 | 0.0383459 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0382593 |
| KYNU | kynureninase | 0.0380045 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0375646 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0374265 |
| SEPTIN9 | septin 9 | 0.0369199 |
| VEGFA | vascular endothelial growth factor A | 0.0361212 |
| ACTN4 | actinin, alpha 4 | 0.0357231 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355865 |
| YBX3 | Y box binding protein 3 | 0.0352907 |
| ETV6 | ets variant 6 | 0.0348375 |
| EFNB2 | ephrin-B2 | 0.0340305 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0338994 |
| DSPP | dentin sialophosphoprotein | 0.0338831 |
| APP | amyloid beta (A4) precursor protein | 0.0337118 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0336644 |
| KRT18 | keratin 18, type I | 0.0334652 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0331491 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0329413 |
| APOL2 | apolipoprotein L, 2 | 0.0328599 |
| HLA-C | major histocompatibility complex, class I, C | 0.0326973 |
| ITGA6 | integrin, alpha 6 | 0.0324091 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0320925 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0319174 |
| TRERF1 | transcriptional regulating factor 1 | 0.0318582 |
| PRSS22 | protease, serine, 22 | 0.0314023 |
| SFTPA2 | surfactant protein A2 | 0.0313334 |
| SDC4 | syndecan 4 | 0.0313245 |
| NIBAN2 | niban apoptosis regulator 2 | 0.031176 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0307753 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0305252 |
| ATP10B | ATPase, class V, type 10B | 0.0296539 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0294346 |
| STK24 | serine/threonine kinase 24 | 0.0293872 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0293802 |
| ACTG1 | actin gamma 1 | 0.0293553 |
| CTBP2 | C-terminal binding protein 2 | 0.0292564 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0291529 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0290332 |
| ANXA11 | annexin A11 | 0.0289006 |
| RRBP1 | ribosome binding protein 1 | 0.028759 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.028683 |
| MINK1 | misshapen-like kinase 1 | 0.0279486 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0277915 |
| IFNGR1 | interferon gamma receptor 1 | 0.0277852 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0276487 |
| BCL2L1 | BCL2-like 1 | 0.0274892 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0271873 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0271013 |
| MYO18A | myosin XVIIIA | 0.0270102 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0267412 |
| CGN | cingulin | 0.026444 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0262975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.12309 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116213 |
| LYZ | lysozyme | -0.105901 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0853748 |
| NPSR1 | neuropeptide S receptor 1 | -0.0818978 |
| INTS6 | integrator complex subunit 6 | -0.080329 |
| SP100 | SP100 nuclear antigen | -0.0757196 |
| XAF1 | XIAP associated factor 1 | -0.0714637 |
| VCL | vinculin | -0.0705509 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0696344 |
| AHI1 | Abelson helper integration site 1 | -0.0690564 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0650529 |
| PHF3 | PHD finger protein 3 | -0.0633087 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0627007 |
| PLSCR2 | phospholipid scramblase 2 | -0.0619769 |
| PLSCR1 | phospholipid scramblase 1 | -0.0617925 |
| EGR1 | early growth response 1 | -0.0616574 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0570591 |
| TXNIP | thioredoxin interacting protein | -0.0568269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0557837 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0554224 |
| ERBIN | erbb2 interacting protein | -0.0554109 |
| GOLGB1 | golgin B1 | -0.0553936 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0553898 |
| PTMA | prothymosin, alpha | -0.0546708 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0544213 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0536727 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0529161 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0526542 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0517648 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0490206 |
| FNDC3B | fibronectin type III domain containing 3B | -0.047272 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0472564 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0457276 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0452457 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0447251 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0447216 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0443762 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0442237 |
| FNIP1 | folliculin interacting protein 1 | -0.0436767 |
| RIGI | RNA sensor RIG-I | -0.0435422 |
| ANXA2 | annexin A2 | -0.0430799 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0424192 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0420674 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0418923 |
| UBC | ubiquitin C | -0.0409806 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0400396 |
| ZNF292 | zinc finger protein 292 | -0.0397356 |
| MUC20 | mucin 20, cell surface associated | -0.0392099 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.038587 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0378718 |
| VMP1 | vacuole membrane protein 1 | -0.0378491 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0366797 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0365445 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0356382 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.035219 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0351419 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0333768 |
| NF1 | neurofibromin 1 | -0.0333361 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.033056 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0330275 |
| PMP22 | peripheral myelin protein 22 | -0.0330178 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0329711 |
| HM13 | histocompatibility (minor) 13 | -0.0323092 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0320151 |
| COG6 | component of oligomeric golgi complex 6 | -0.0311978 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0308348 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0305448 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0305265 |
| POF1B | premature ovarian failure, 1B | -0.0303758 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0302225 |
| SSH2 | slingshot protein phosphatase 2 | -0.0296933 |
| CDK13 | cyclin-dependent kinase 13 | -0.0294252 |
| GNAS | GNAS complex locus | -0.0289231 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0287783 |
| GOLGA4 | golgin A4 | -0.028772 |
| MCU | mitochondrial calcium uniporter | -0.0287348 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0286447 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0284721 |
| SCFD1 | sec1 family domain containing 1 | -0.028257 |
| USP53 | ubiquitin specific peptidase 53 | -0.0281578 |
| FBXO39 | F-box protein 39 | -0.0281361 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0276984 |
| RBM39 | RNA binding motif protein 39 | -0.0274579 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0274256 |
| NDRG1 | N-myc downstream regulated 1 | -0.0269633 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0268972 |
| UBAP2 | ubiquitin associated protein 2 | -0.026671 |
| APOL6 | apolipoprotein L, 6 | -0.026541 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0265181 |
| RPL34 | ribosomal protein L34 | -0.0264643 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0264083 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263669 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0263495 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0263189 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0262697 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0262514 |
| SBF2 | SET binding factor 2 | -0.026229 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0259085 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0255835 |
