| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.495845 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0804843 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.078188 |
| LDHA | lactate dehydrogenase A | 0.0666205 |
| PLEC | plectin | 0.0590159 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0583985 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0561071 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0560296 |
| FTL | ferritin, light polypeptide | 0.0543436 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0530733 |
| HLA-B | major histocompatibility complex, class I, B | 0.0528824 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0478687 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0476859 |
| CALR | calreticulin | 0.0476541 |
| APP | amyloid beta (A4) precursor protein | 0.0445076 |
| MT2A | metallothionein 2A | 0.0439825 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0418402 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0400257 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0399402 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.039907 |
| B2M | beta-2-microglobulin | 0.0389589 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0386407 |
| NONO | non-POU domain containing, octamer-binding | 0.038333 |
| ACTN1 | actinin, alpha 1 | 0.0381455 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0374458 |
| SON | SON DNA binding protein | 0.035615 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.035129 |
| SDC4 | syndecan 4 | 0.0336501 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.032738 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0322463 |
| FLNA | filamin A, alpha | 0.030883 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0305774 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0305743 |
| PRELID2 | PRELI domain containing 2 | 0.030443 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0287708 |
| CPNE1 | copine I | 0.0285843 |
| COL5A1 | collagen, type V, alpha 1 | 0.0281726 |
| DST | dystonin | 0.0278058 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0271788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0271046 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0269385 |
| DBN1 | drebrin 1 | 0.0269195 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0268599 |
| MAP1B | microtubule-associated protein 1B | 0.0264345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0263334 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0261925 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0258904 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0251355 |
| TUBB | tubulin, beta class I | 0.0249522 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.024373 |
| RPL3 | ribosomal protein L3 | 0.0243279 |
| PRRC2A | proline-rich coiled-coil 2A | 0.024254 |
| SETBP1 | SET binding protein 1 | 0.0235829 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.023536 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0235248 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0234553 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0232694 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0225456 |
| TXNRD1 | thioredoxin reductase 1 | 0.0223412 |
| MT1X | metallothionein 1X | 0.0221275 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0219397 |
| SFTPA2 | surfactant protein A2 | 0.0216262 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0213362 |
| CEP250 | centrosomal protein 250kDa | 0.0203301 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0203074 |
| TMSB4X | thymosin beta 4, X-linked | 0.0200996 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0200939 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0200535 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0199259 |
| AOPEP | aminopeptidase O (putative) | 0.0199162 |
| HYOU1 | hypoxia up-regulated 1 | 0.0196523 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0193211 |
| ASPH | aspartate beta-hydroxylase | 0.019217 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0191753 |
| WLS | wntless Wnt ligand secretion mediator | 0.0191736 |
| DIDO1 | death inducer-obliterator 1 | 0.0191595 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0190544 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0189537 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0188599 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0186966 |
| MSN | moesin | 0.0186369 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0185694 |
| COL13A1 | collagen, type XIII, alpha 1 | 0.0185503 |
| HLA-C | major histocompatibility complex, class I, C | 0.0184518 |
| MLPH | melanophilin | 0.0183926 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0183678 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0182623 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.018206 |
| RPLP0 | ribosomal protein, large, P0 | 0.0181855 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0181563 |
| NAV2 | neuron navigator 2 | 0.0180667 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0180566 |
| SF1 | splicing factor 1 | 0.0180424 |
| IL6ST | interleukin 6 signal transducer | 0.0180167 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0179437 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0179252 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0179157 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0176811 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0175366 |
| CLIC4 | chloride intracellular channel 4 | 0.0173255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.306048 |
| FN1 | fibronectin 1 | -0.121027 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.098382 |
| VIM | vimentin | -0.0885216 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0706281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.070463 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0695484 |
| LOX | lysyl oxidase | -0.0695342 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0686087 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0674866 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0659591 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.063649 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0617187 |
| EGFR | epidermal growth factor receptor | -0.0562476 |
| GNAS | GNAS complex locus | -0.054087 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0525247 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0523409 |
| CALD1 | caldesmon 1 | -0.0492832 |
| FNIP1 | folliculin interacting protein 1 | -0.0482646 |
| DTNA | dystrobrevin, alpha | -0.0482565 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0473323 |
| MMP12 | matrix metallopeptidase 12 | -0.0468198 |
| GOLGB1 | golgin B1 | -0.0467484 |
| SEC24A | SEC24 family member A | -0.0461997 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0444284 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0427071 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0425129 |
| GOLGA4 | golgin A4 | -0.0425109 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0424848 |
| CLMP | CXADR-like membrane protein | -0.0421016 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0419983 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0419443 |
| SBF2 | SET binding factor 2 | -0.0410349 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0399726 |
| TPM4 | tropomyosin 4 | -0.0398555 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0392401 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0384196 |
| CDK13 | cyclin-dependent kinase 13 | -0.0371386 |
| COPA | coatomer protein complex, subunit alpha | -0.0363721 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0361945 |
| SCFD1 | sec1 family domain containing 1 | -0.0360691 |
| TNS3 | tensin 3 | -0.0358977 |
| RAB1A | RAB1A, member RAS oncogene family | -0.035728 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0356738 |
| USP34 | ubiquitin specific peptidase 34 | -0.0355435 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.034318 |
| RTN4 | reticulon 4 | -0.0341961 |
| COG5 | component of oligomeric golgi complex 5 | -0.0341543 |
| SRP54 | signal recognition particle 54kDa | -0.0333546 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.033343 |
| PTMA | prothymosin, alpha | -0.0320252 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0319794 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0319141 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0315921 |
| POTEF | POTE ankyrin domain family, member F | -0.0315908 |
| NDRG1 | N-myc downstream regulated 1 | -0.0315428 |
| CLINT1 | clathrin interactor 1 | -0.0313157 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0301398 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0301183 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300779 |
| HIP1 | huntingtin interacting protein 1 | -0.0296145 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0295452 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0295439 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0295348 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0294784 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0292262 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0290031 |
| CD99 | CD99 molecule | -0.0288644 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.028687 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0285491 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0283633 |
| SUCO | SUN domain containing ossification factor | -0.0279076 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0277885 |
| FAM13A | family with sequence similarity 13, member A | -0.0276983 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.027259 |
| IGF2 | insulin-like growth factor 2 | -0.0267001 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0265486 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0264924 |
| HELZ | helicase with zinc finger | -0.0264393 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0262398 |
| INHBA | inhibin, beta A | -0.0262 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0260267 |
| BBX | bobby sox homolog (Drosophila) | -0.0256359 |
| CUX1 | cut-like homeobox 1 | -0.025513 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0254531 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0253728 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249255 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0249011 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0248128 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248057 |
| ASTN2 | astrotactin 2 | -0.0247836 |
| TMEM263 | transmembrane protein 263 | -0.0247326 |
| RPS6 | ribosomal protein S6 | -0.0247267 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0243269 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0241965 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0240641 |
| ZNF638 | zinc finger protein 638 | -0.0240618 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0240381 |
| MAP4 | microtubule-associated protein 4 | -0.0238614 |
| NOTCH2 | notch 2 | -0.0238103 |
