| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Riluzole hydrochloride perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Riluzole hydrochloride_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.181057 |
| NDRG1 | N-myc downstream regulated 1 | 0.122124 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.102806 |
| KRT18 | keratin 18, type I | 0.0767942 |
| FAT1 | FAT atypical cadherin 1 | 0.0752453 |
| ENO1 | enolase 1, (alpha) | 0.0737203 |
| KRT8 | keratin 8, type II | 0.0728652 |
| TMSB10 | thymosin beta 10 | 0.0726244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0683651 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0666487 |
| RRM2 | ribonucleotide reductase M2 | 0.0634621 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0619371 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0456026 |
| PLEC | plectin | 0.045508 |
| VEGFA | vascular endothelial growth factor A | 0.0448015 |
| RPL3 | ribosomal protein L3 | 0.0422947 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0387837 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0381899 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375661 |
| CTBP2 | C-terminal binding protein 2 | 0.0365425 |
| TPM3 | tropomyosin 3 | 0.0335051 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0322691 |
| MT2A | metallothionein 2A | 0.0318609 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0318194 |
| NONO | non-POU domain containing, octamer-binding | 0.0314749 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0307653 |
| TUBA1B | tubulin, alpha 1b | 0.0305091 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0301265 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0299668 |
| FN1 | fibronectin 1 | 0.0295619 |
| PKM | pyruvate kinase, muscle | 0.0294409 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282635 |
| DSPP | dentin sialophosphoprotein | 0.0278375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275672 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267084 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0264316 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0263476 |
| MKI67 | marker of proliferation Ki-67 | 0.025725 |
| LDHA | lactate dehydrogenase A | 0.0254054 |
| ADM | adrenomedullin | 0.0251658 |
| ANXA11 | annexin A11 | 0.0249652 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.024436 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.024413 |
| FLNA | filamin A, alpha | 0.0235903 |
| YBX1 | Y box binding protein 1 | 0.0233145 |
| SET | SET nuclear proto-oncogene | 0.02308 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0230048 |
| MINK1 | misshapen-like kinase 1 | 0.0227931 |
| DIAPH3 | diaphanous-related formin 3 | 0.0221645 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0214089 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0209452 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0208884 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0207805 |
| SFTPA2 | surfactant protein A2 | 0.0201623 |
| PGK1 | phosphoglycerate kinase 1 | 0.0201333 |
| ASPH | aspartate beta-hydroxylase | 0.0200207 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0199708 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0198983 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0198763 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0198235 |
| CD9 | CD9 molecule | 0.0195916 |
| ANGPTL4 | angiopoietin-like 4 | 0.0194545 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0193454 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.01928 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0192487 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0192395 |
| ITGB4 | integrin, beta 4 | 0.0191819 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0190021 |
| MED15 | mediator complex subunit 15 | 0.018717 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0187097 |
| TUBB | tubulin, beta class I | 0.0186995 |
| WWOX | WW domain containing oxidoreductase | 0.0182501 |
| SNX9 | sorting nexin 9 | 0.0182259 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0181789 |
| B2M | beta-2-microglobulin | 0.0181126 |
| H1-2 | H1.2 linker histone, cluster member | 0.0178557 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.017639 |
| LMNA | lamin A/C | 0.0176144 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0175668 |
| CBX5 | chromobox homolog 5 | 0.0173426 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0171972 |
| ARGLU1 | arginine and glutamate rich 1 | 0.016958 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0169355 |
| PCNT | pericentrin | 0.0168771 |
| SEPTIN7 | septin 7 | 0.0168146 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0167081 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0166956 |
| INTS1 | integrator complex subunit 1 | 0.0166505 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0164763 |
| H1-4 | H1.4 linker histone, cluster member | 0.0164255 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0164134 |
| HLA-B | major histocompatibility complex, class I, B | 0.0164018 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0163928 |
| CEP250 | centrosomal protein 250kDa | 0.0163043 |
| PFKP | phosphofructokinase, platelet | 0.0162246 |
| SEPTIN9 | septin 9 | 0.0161956 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0160312 |
| ANLN | anillin, actin binding protein | 0.0159948 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0159754 |
| ZNF395 | zinc finger protein 395 | 0.0159646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.24198 |
| TXNRD1 | thioredoxin reductase 1 | -0.11282 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0871845 |
| VCL | vinculin | -0.0845619 |
| NF1 | neurofibromin 1 | -0.0782201 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0697553 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.069412 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0682054 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0667236 |
| SQSTM1 | sequestosome 1 | -0.0623035 |
| RBM39 | RNA binding motif protein 39 | -0.0622871 |
| SMYD3 | SET and MYND domain containing 3 | -0.0620283 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0597888 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.059497 |
| TENM3 | teneurin transmembrane protein 3 | -0.0589171 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0585196 |
| GPHN | gephyrin | -0.0577566 |
| EZR | ezrin | -0.0576991 |
| CANX | calnexin | -0.0571868 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0566465 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0565097 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0547095 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0540261 |
| AHNAK | AHNAK nucleoprotein | -0.0531247 |
| HDLBP | high density lipoprotein binding protein | -0.0521744 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0521595 |
| JMJD1C | jumonji domain containing 1C | -0.0521194 |
| VMP1 | vacuole membrane protein 1 | -0.0509828 |
| ARF4 | ADP-ribosylation factor 4 | -0.0507799 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0506494 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0505361 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0502081 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0499143 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0498271 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0491211 |
| BPTF | bromodomain PHD finger transcription factor | -0.0489922 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0487401 |
| CDK13 | cyclin-dependent kinase 13 | -0.0476885 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0463263 |
| GOLGB1 | golgin B1 | -0.044967 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0449305 |
| PAPOLA | poly(A) polymerase alpha | -0.044645 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0443705 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0437058 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0431186 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0430008 |
| ZNF638 | zinc finger protein 638 | -0.04289 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0427415 |
| SBF2 | SET binding factor 2 | -0.0427337 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0421112 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0419978 |
| CD2AP | CD2-associated protein | -0.0413825 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0410546 |
| TCF12 | transcription factor 12 | -0.040267 |
| SLC38A2 | solute carrier family 38, member 2 | -0.040044 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0396648 |
| ATM | ATM serine/threonine kinase | -0.0390475 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.03892 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0388729 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0384566 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0384167 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0378282 |
| NBEAL1 | neurobeachin-like 1 | -0.0378168 |
| NOP58 | NOP58 ribonucleoprotein | -0.0375029 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0372777 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.037064 |
| MAP4 | microtubule-associated protein 4 | -0.0367879 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0361017 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0359975 |
| WDR26 | WD repeat domain 26 | -0.0358632 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0357271 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0355292 |
| RBM25 | RNA binding motif protein 25 | -0.035129 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.035125 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0350498 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0349886 |
| OGA | O-GlcNAcase | -0.0349877 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0346601 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0344823 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0343849 |
| EXOC6B | exocyst complex component 6B | -0.0343745 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0343596 |
| GOLGA4 | golgin A4 | -0.0342271 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0341379 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0338306 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0333236 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332748 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.032464 |
| NEBL | nebulette | -0.0324272 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0322942 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0322322 |
| MED13L | mediator complex subunit 13-like | -0.0319819 |
| TUT4 | terminal uridylyl transferase 4 | -0.0319107 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0316499 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.0316442 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0316085 |
| KLF6 | Kruppel-like factor 6 | -0.0313201 |
| HM13 | histocompatibility (minor) 13 | -0.0313188 |
| AK1 | adenylate kinase 1 | -0.0313147 |
| COPA | coatomer protein complex, subunit alpha | -0.0312217 |
